An article Preparation of chiral alcohols by enantioselective reduction of prochiral ketones with Sinapis alba seeds as biocatalyst WOS:000496611800080 published article about PLANT FRAGMENTS; BIOREDUCTION; CARBONYL; LIPASE; NANOPARTICLES; BIOSYNTHESIS; BIODIESEL; ALDEHYDES; REACTOR; ESTERS in [Almeida de Sousa, Emerson Yvay; Gomes de Lemos, Telma Leda; Queiroz Monte, Francisco Jose] Univ Fed Ceara, Sci Ctr, Program Postgrad Chem, Pici Campus, BR-60455760 Fortaleza, Ceara, Brazil; [Maia da Silva, Francisco Felipe] Fed Inst Educ Sci & Technol Rio Grande Norte, Campus Apodi, BR-59700000 Bento Goncalves, RN, Brazil; [Oliveira de Souza, Juliana Maria] Fed Inst Educ Sci & Technol Ceara, Campus Acarau, BR-62580000 Limoeiro Do Norte, CE, Brazil; [Ferreira, Daniele Alves] Univ Int Integrat Lusofonia Afro Brasileira UNILA, Campus Auroras, BR-62790970 Redencao, CE, Brazil in 2019.0, Cited 44.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6
The objective of this work is to apply yellow mustard seeds in the enzymatic reduction (biocatalysis) of acetophenone and its derivatives, providing a new biocatalyst for this type of reduction. The reaction parameters were optimized from acetophenone, resulting in 1-phenylethanol, with 68.5% conversion yield and 53% enantiomeric excess (e.e.), analyzed by GC and HPLC, respectively. Reactions to acetophenone and its derivatives were conducted in aqueous medium using buffers pH 6.0 and pH 6.5 in the presence of PVP. A polymer that can act as a protector preventing oxidation of peroxidase enzymes. The results for the derivatives presented low yields (4-18%: substances 5, 7 and 8), moderate (28-40%: substances 3, 4 and 6) and optimum (81%: substance 2) yields, with enantiomeric excesses varying from good to excellent results. Meta-substituted derivatives showed inversion of configuration in the presence of PVP. The biocatalyst was also tested in reactions with other carbonyl compounds, presenting moderate results. In this way, this work offers a new perspective of the application of PVP in biocatalysis reactions and a new biocatalyst for future applications.
Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact de Sousa, EYA; da Silva, FFM; de Souza, JMO; Ferreira, DA; de Lemos, TLG; Monte, FJQ or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem