As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. Quality Control of Methyl 1,4-Benzodioxane-2-carboxylate, In a article, mentioned the application of 3663-79-4, Name is Methyl 1,4-Benzodioxane-2-carboxylate, molecular formula is C10H10O4
Unlike the diastereomeric 1-phenylethylammonium salts, the diastereomeric N-1-phenylethylamides of (S)- and (R)-1,4-benzodioxane-2-carboxylic acid show significant differences in fusibility and solubility so as to be efficiently resolved by precipitation of the less soluble diastereomer (>98% de), while chromatographic purification of the unprecipitated fraction affords the more soluble one (>99% de). Overall, 95% of the former and 80% of the latter are recovered. The hydrolysis of the two resolved amides provides the two acid enantiomers and the resolving amine in quantitative yield and with unchanged stereoisomeric purity.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of Methyl 1,4-Benzodioxane-2-carboxylate, you can also check out more blogs about3663-79-4
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem