I found the field of Chemistry; Science & Technology – Other Topics; Engineering very interesting. Saw the article One-Step Synthesis of Thieno[2,3-d]pyrimidin-4(3H)-ones via a Catalytic Four-Component Reaction of Ketones, Ethyl Cyanoacetate, S-8, and Formamide published in 2019.0. SDS of cas: 100-19-6, Reprint Addresses Chapman, E (corresponding author), Univ Arizona, Dept Pharmacol & Toxicol, Coll Pharm, 1703 East Mabel St,POB 210207, Tucson, AZ 85721 USA.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
Thieno[2,3-d]pyrimidin-4(3H)-ones are important pharmacophores that have previously required a three-step synthesis with two chromatography steps. We herein report a green approach to the synthesis of this pharmacologically important class of compounds via a catalytic four-component reaction using a ketone, ethyl cyanoacetate, S-8, and formamide. The reported reaction is characterized by step economy, reduced catalyst loading, and easy purification.
SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shi, TD; Kaneko, L; Sandino, M; Busse, R; Zhang, M; Mason, D; Machulis, J; Ambrose, AJ; Zhang, DD; Chapman, E or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem