An article Enantioselective N -Alkylation of Nitroindoles under Phase-Transfer Catalysis WOS:000526537000009 published article about AZA-MICHAEL REACTIONS; ASYMMETRIC-SYNTHESIS; RECENT PROGRESS; INDOLES; FUNCTIONALIZATION; ACTIVATION; ALDEHYDES; ANALOGS; ALKENES; ENONES in [Trubitson, Dmitri; Martonova, Jevgenija; Erkman, Kristin; Metsala, Andrus; Jarving, Ivar; Kanger, Tonis] Tallinn Univ Technol, Dept Chem & Biotechnol, EE-12618 Tallinn, Estonia; [Saame, Jaan; Koster, Kristjan; Leito, Ivo] Univ Tartu, Inst Chem, EE-50411 Tartu, Estonia in 2020.0, Cited 53.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone
An asymmetric phase-transfer-catalyzed N -alkylation of substituted indoles with various Michael acceptors was studied. Acidities of nitroindoles were determined in acetonitrile by UV-Vis spectrophotometric titration. There was essentially no correlation between acidity and reactivity in the aza-Michael reaction. The position of the nitro group on the indole ring was essential to control the stereoselectivity of the reaction. Michael adducts were obtained in high yields and moderate enantioselectivities in the reaction between 4-nitroindole and various Michael acceptors in the presence of cinchona alkaloid based phase-transfer catalysts. In addition to outlining the scope and limitations of the method, the geometries of the transition states of the reaction were calculated.
Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Trubitson, D; Martonova, J; Erkman, K; Metsala, A; Saame, J; Koster, K; Jarving, I; Leito, I; Kanger, T or send Email.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem