I found the field of Chemistry very interesting. Saw the article Green one-pot multicomponent synthesis, biological evaluation and theoretical investigations of some novel beta-acetamido ketone derivatives as potent cholinesterase inhibitors published in 2020.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone, Reprint Addresses Boulcina, R; Debache, A (corresponding author), Mentouri Constantine 1 Univ, Lab Synth Mol Biol Interest, Constantine 25000, Algeria.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
A series of novel beta-acetamido ketones have been prepared via a four-component condensation between aromatic aldehydes, enolizable ketones, acyl chloride and acetonitrile in the presence of 10 mol% of phenylboronic acid as a catalyst. The expected products have been obtained in good to excellent yields. In addition, in vitro cholinesterase inhibitory activity of title compounds has been studied and the results indicated that some compounds exhibited remarkable BChE activity. In order to gain insights into the molecular structure and chemical reactivity of the synthesized beta-acetamido ketones, density functional theory (DFT) calculations were also carried out. (C) 2020 Elsevier Ltd. All rights reserved.
Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chibane, AZ; Boulcina, R; Boulebd, H; Bensouici, C; Yildirim, M; Debache, A or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem