One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Safety of 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 214894-89-0, Name is 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, molecular formula is C9H9BrO2
3-Hydroxypyrimidine-2,4-diones as an Inhibitor Scaffold of HIV Integrase
Integrase (IN) represents a clinically validated target for the development of antivirals against human immunodeficiency virus (HIV). Inhibitors with a novel structure core are essential for combating resistance associated with known IN inhibitors (INIs). We have previously disclosed a novel dual inhibitor scaffold of HIV IN and reverse transcriptase (RT). Here we report the complete structure-activity relationship (SAR), molecular modeling, and resistance profile of this inhibitor type on IN inhibition. These studies support an antiviral mechanism of dual inhibition against both IN and RT and validate 3-hydroxypyrimidine-2,4-diones as an IN inhibitor scaffold.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Safety of 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 214894-89-0, in my other articles.
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem