Computed Properties of C8H7NO3. Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M in [Massolo, Elisabetta; Pirola, Margherita; Puglisi, Alessandra; Rossi, Sergio; Benaglia, Maurizio] Univ Milan, Dipartimento Chim, Via Golgi 19, I-20133 Milan, Italy published A one pot protocol to convert nitro-arenes into N-aryl amides in 2020, Cited 42. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.
A two-step one pot, experimentally simple protocol, based on readily available and inexpensive reagents allowed the conversion of nitro-arenes directly to N-aryl amides. A metal-free reduction of the nitro group, mediated by trichlorosilane, followed by the addition of an anhydride afforded the corresponding N-aryl carboxyamide, that was isolated after a simple aqueous work up in good-excellent yields. When the methodology was applied to the reaction with gamma-butyrolactone, the desired N-aryl butanamide derivative was obtained, featuring a chlorine atom at the gamma-position, a functionalized handle that can be used for further synthetic manipulation of the reaction product. Such an intermediate has already been employed as a key advanced precursor of pharmaceutically active compounds.
About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M or concate me.. Computed Properties of C8H7NO3
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Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem