Tag: M.W=150-200

An article Organotellurium-catalyzed oxidative deoximation reactions using visible-light as the precise driving energy WOS:000642405100005 published article about CARBONYL-COMPOUNDS; AEROBIC OXIDATION; OXIMES; QUINOXALIN-2(1H)-ONES; DEPROTECTION; PHOTOCATALYST; ALCOHOLS; OXIDANT; KETONES; METAL in [Deng, Xin; Yu, Lei] Yangzhou Univ, Sch Chem & Chem Engn, Yangzhou 225002, Jiangsu, Peoples R China; [Deng, Xin; Zhou, Hongwei] Jiaxing Univ, Coll Biol Chem Sci & Engn, Jiaxing 314001, Peoples R China; [Qian, Rongrong] Jiangsu Coll Tourism, Yangzhou 225127, Jiangsu, Peoples R China in 2021, Cited 57. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

Irradiated by visible light, the recyclable (PhTe)(2)-catalyzed oxidative deoximation reaction could occur under mild conditions. In comparison with the thermo reaction, the method employed reduced catalyst loading (1 mol% vs. 2.5 mol%), but afforded elevated product yields with expanded substrate scope. This work demonstrated that for the organotellurium-catalyzed reactions, visible light might be an even more precise driving energy than heating because it could break the Te-Te bond accurately to generate the active free radical catalytic intermediates without damaging the fragile substituents (e.g., heterocycles) of substrates. The use of O-2 instead of explosive H2O2 as oxidant affords safer reaction conditions from the large-scale application viewpoint. (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Name: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis of bis(indolyl)methanes under dry grinding conditions, promoted by a Lewis acid-surfactant-SiO2-combined nanocatalyst WOS:000474622600003 published article about ORGANIC-SYNTHESIS; HIGHLY EFFICIENT; ACID; CATALYST; WATER; DERIVATIVES; COCATALYST; COMPOSITE; CHEMISTRY in [Wu, Zhiqiang; Wang, Gang; Yuan, Shuo; Wu, Dan; Liu, Wanyi; Ma, Baojun; Bi, Shuxian; Zhan, Haijuan; Chen, Xiaoyan] Ningxia Univ, Coll Chem & Chem Engn, Natl Demonstrat Ctr Expt Chem Educ, State Key Lab High Efficiency Utilizat Coal & Gre, Yinchuan 750021, Peoples R China in 2019.0, Cited 40.0. HPLC of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

An in situ developed Lewis acid-surfactant-SiO2-combined (LASSC) nanocatalyst was used, for the first time, as a green and effective promoting medium for the electrophilic activation of aldehydes under solvent-free and dry grinding conditions. The advantages of using the LASSC nanocatalyst include avoiding the generation of wastewater containing sodium dodecyl sulfate and the use of toxic reagents, excellent reusability of the catalyst, and obtaining a high yield of bis(indolyl)methanes.

Welcome to talk about 100-19-6, If you have any questions, you can contact Wu, ZQ; Wang, G; Yuan, S; Wu, D; Liu, WY; Ma, BJ; Bi, SX; Zhan, HJ; Chen, XY or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. In 2020.0 J MED CHEM published article about MOLECULAR-DYNAMICS SIMULATIONS; DRUG DISCOVERY; RESISTANCE; ACCURACY; AMBER; GAMETOCYTES; DESIGN in [Hammill, Jared T.; Rice, Amy L.; Falade, Mofolusho O.; Guy, R. Kiplin] Univ Kentucky, Dept Pharmaceut Sci, Lexington, KY 40508 USA; [Sigal, Martina] St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, 332 N Lauderdale St, Memphis, TN 38105 USA; [Eagon, Scott; Ahn, Kevin J.; Tryhorn, Julia E.; Belanger, Briana; Chaplan, Cory A.; Loop, Lauren; Kashtanova, Anna S.; Wilkinson, Steven P.; Takahashi, Rei; Kim, Katie; Cheung, Ashley; DiBernardo, Celine] Calif Polytech State Univ San Luis Obispo, Dept Chem & Biochem, San Luis Obispo, CA 93407 USA; [Koch, Grant] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA; [Yniguez, Kenya] SRI Int, Menlo Pk, CA 94025 USA; [Lazaro, Horacio; Kimball, Joshua J.] Promega Biosci, San Luis Obispo, CA 93401 USA; [Winzeler, Elizabeth A.; Eribez, Korina; Mittal, Nimisha] Univ Calif San Diego, Sch Med, La Jolla, CA 92093 USA; [Gamo, Francisco-Javier; Crespo, Benigno] GlaxoSmithKline, DDW, Global Hlth, Madrid 28760, Spain; [Churchyard, Alisje; Garcia-Barbazan, Irene; Baum, Jake] Imperial Coll London, Dept Life Sci, London SW7 2AZ, England; [Anderson, Marc O.] San Francisco State Univ, Dept Chem & Biochem, San Francisco, CA 94132 USA; [Laleu, Benoit] Med Malaria Venture MMV, CH-1215 Geneva, Switzerland in 2020.0, Cited 56.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Malaria remains one of the most deadly infectious diseases, causing hundreds of thousands of deaths each year, primarily in young children and pregnant mothers. Here, we report the discovery and derivatization of a series of pyrazolo[3,4-b]pyridines targeting Plasmodium falciparum, the deadliest species of the malaria parasite. Hit compounds in this series display sub-micromolar in vitro activity against the intraerythrocytic stage of the parasite as well as little to no toxicity against the human fibroblast BJ and liver HepG2 cell lines. In addition, our hit compounds show good activity against the liver stage of the parasite but little activity against the gametocyte stage. Parasitological profiles, including rate of killing, docking, and molecular dynamics studies, suggest that our compounds may target the Q(o) binding site of cytochrome bc(1).

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Eagon, S; Hammill, JT; Sigal, M; Ahn, KJ; Tryhorn, JE; Koch, G; Belanger, B; Chaplan, CA; Loop, L; Kashtanova, AS; Yniguez, K; Lazaro, H; Wilkinson, SP; Rice, AL; Falade, MO; Takahashi, R; Kim, K; Cheung, A; DiBernardo, C; Kimball, JJ; Winzeler, EA; Eribez, K; Mittal, N; Gamo, FJ; Crespo, B; Churchyard, A; Garcia-Barbazan, I; Baum, J; Anderson, MO; Laleu, B; Guy, RK or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Rh(III)-Catalyzed Direct Amination of Aromatic Ketoximes Enabled by Potassium Acetate WOS:000505254600011 published article about C-H BONDS; INTERMOLECULAR AMIDATION; REGIOSPECIFIC SYNTHESIS; OXIME ETHER; NITROARENES; CYCLIZATION; ARENES; 1H-INDAZOLES; AZOBENZENES; ACTIVATION in [Liu, Lingling; Wang, Ning; Dai, Chenyang; Han, Yi; Yang, Shan; Huang, Zhibin; Zhao, Yingsheng] Soochow Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, 199 Renai St, Suzhou 215123, Jiangsu, Peoples R China in 2019.0, Cited 54.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

A method to achieve rhodium(III)-catalyzed, potassium acetate enabled intermolecular C-H amination of ketoximes using various benzenesulfonamide, especially 4-nitrobenzenesulfonamide is reported. Various aryl ketoximes substituted with electron-withdrawing functional groups were all well tolerated and produced the corresponding products in moderate to good yields. A preliminary mechanistic study revealed that potassium acetate is essential to realizing intermolecular amination.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Solvent and additive-free efficient aerobic oxidation of alcohols by a perovskite oxide-based heterogeneous catalyst WOS:000545260900006 published article about SELECTIVE OXIDATION; GOLD NANOPARTICLES; ORGANIC FRAMEWORKS; BENZYLIC ALCOHOLS; LACTONIZATION; MECHANISM; WATER; ALDEHYDES; SURFACE; FACILE in [Kumar, Nikhil; Naveen, Kumari; Bhatia, Anita; Muthaiah, Senthilkumar; Paul, Avijit Kumar] Natl Inst Technol, Dept Chem, Kurukshetra 136119, Haryana, India; [Siruguri, Vasudeva] UGC DAE Consortium Sci Res Mumbai Ctr, 246-C CFB,BARC Campus, Mumbai 100085, Maharashtra, India in 2020.0, Cited 60.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A new heterogeneous catalyst for the solvent-free efficient oxidation of alcohols has been developed for a sustainable future with a green reaction technology. This work presents the additive and solvent-free catalytic conversions of primary and secondary alcohols as well as diols into their corresponding carbonyl compounds in moderate to excellent yields. The developed catalyst system is green as it oxidises alcohols under solvent-free conditions and uses simple atmospheric oxygen as the oxidising agent. We have experimentally proved that the alcohol oxidation reaction proceeds through an aerobic oxidative pathway. The double perovskite oxide catalyst CaLaScRuO(6+delta)was prepared by the conventional solid-state method. The crystal structure was refined and characterized thoroughly to observe the effect of mixed valent Ru5+/Ru(4+)ions in the oxygen-rich disordered structure. The conversion of diols into four-, five- and six-membered lactones can enhance the novelty of the present catalyst. The catalyst was found to be very selective for the alcohol oxidation and resulted in the oxidised product without affecting the other functional groups present in the aromatic ring. A reaction mechanism has been proposed for understanding the possible role of mixed metals in heterogeneous catalysis.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Kumar, N; Naveen, K; Bhatia, A; Muthaiah, S; Siruguri, V; Paul, AK or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Sadjadi, S; Heravi, MM; Kahangi, FG in [Sadjadi, Samahe] Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, POB 14975-112, Tehran, Iran; [Heravi, Majid M.] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran; [Kahangi, Fatemeh Ghoreyshi] Univ Guilan, Dept Chem, Univ Campus 2, Rasht, Iran published Salep as a biological source for the synthesis of biochar with utility for the catalysis in 2019.0, Cited 52.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Hydrothermal carbonization of salep as a domestic biosource was carried out to afford a biochar, BC, with exceptional catalytic activity. BC can be further magnetized by incorporation of magnetic nanoparticles to furnish a magnetic catalyst, BC-Fe, with improved recovery and recyclability for the hydrogenation of nitroarenes in the absence of any precious metal. BC-Fe was also applied as a catalyst support for the immobilization of Pd nanoparticles and development of an efficient, biocompatible and cost-effective catalyst, Pd@BC-Fe, with utility for the oxidation of benzyl alcohols under mild reaction condition in a selective manner to afford corresponding acids in high yields. The study of the recyclability of the catalyst confirmed high recyclability of Pd@BC-Fe.

Welcome to talk about 100-19-6, If you have any questions, you can contact Sadjadi, S; Heravi, MM; Kahangi, FG or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Luo, XL; He, RF; Liu, Q; Gao, YP; Li, JQ; Chen, XW; Zhu, ZZ; Huang, YB; Li, YB in [Luo, Xianglin; He, Runfa; Liu, Qiang; Gao, Yanping; Li, Jingqing; Chen, Xiuwen; Zhu, Zhongzhi; Huang, Yubing; Li, Yibiao] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529090, Guangdong, Peoples R China; [Liu, Qiang] Tsinghua Univ, Ctr Basic Mol Sci, Dept Chem, Beijing 100084, Peoples R China published Metal-Free Oxidative Esterification of Ketones and Potassium Xanthates: Selective Synthesis of alpha-Ketoesters and Esters in 2020, Cited 74. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A novel and efficient oxidative esterification for the selective synthesis of alpha-ketoesters and esters has been developed under metal-free conditions. In the protocol, various alpha-ketoesters and esters are available in high yields from commercially available ketones and potassium xanthates. Mechanistic studies have proven that potassium xanthate not only promotes oxidative esterification but also provides an alkoxy moiety for the reaction, which involves the cleavage and reconstruction of C-O bonds.

Recommanded Product: 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis of Nitrile-Bearing Quaternary Centers by an Equilibrium-Driven Transnitrilation and Anion-Relay Strategy published in 2019. Recommanded Product: 2,2-Diphenylacetonitrile, Reprint Addresses Rousseaux, SAL (corresponding author), Univ Toronto, Dept Chem, Davenport Res Labs, 80 St George St, Toronto, ON M5S 3H6, Canada.. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

The efficient preparation of nitrile-containing building blocks is of interest due to their utility as synthetic intermediates and their prevalence in pharmaceuticals. As a result, significant efforts have been made to develop methods to access these motifs which rely on safer and non-toxic sources of CN. Herein, we report that 2-methyl-2-phenylpropanenitrile is an efficient, non-toxic, electrophilic CN source for the synthesis of nitrile-bearing quaternary centers by a thermodynamic transnitrilation and anion-relay strategy. This one-pot process leads to nitrile products resulting from the gem-difunctionalization of alkyl lithium reagents.

Recommanded Product: 2,2-Diphenylacetonitrile. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article y Synthesis, Characterization, and Catalytic Reactivity of {CoNO}(8) PCP Pincer Complexes WOS:000557381700006 published article about ORGANOMETALLIC CHEMISTRY; COORDINATION CHEMISTRY; BOND-CLEAVAGE; NITRIC-OXIDE; LIGANDS; PNP; APPROXIMATION; HYDROBORATION; PLATINUM; IRIDIUM in [Pecak, Jan; Eder, Wolfgang; Linert, Wolfgang; Kirchner, Karl] Vienna Univ Technol, Inst Appl Synthet Chem, A-1060 Vienna, Austria; [Stoeger, Berthold] Vienna Univ Technol, Xray Ctr, A-1060 Vienna, Austria; [Realista, Sara] Univ Nova Lisboa, ITQB NOVA, Inst Tecnol Quim & Biol Antonio Xavier, P-2780157 Oeiras, Portugal; [Martinho, Paulo N.; Calhorda, Maria Jose] Univ Lisbon, Fac Ciencias, BioISI Biosyst & Integrat Sci Inst, DQB, P-1749016 Lisbon, Portugal in 2020, Cited 53. Computed Properties of C14H11N. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

The reaction of coordinatively unsaturated Co(II) PCP pincer complexes with nitric oxide leads to the formation of new, air-stable, diamagnetic mono nitrosyl compounds. The synthesis and characterization of five- and four-coordinate Co(III) and Co(I) nitrosyl pincer complexes based on three different ligand scaffolds is described. Passing NO through a solution of [Co(PCPNMe-iPr)Cl], [Co(PCPO-iPr)Cl] or [Co(PCPCH2-iPr)Br] led to the formation of the low-spin complex [Co(PCP-iPr)(NO)-X] with a strongly bent NO ligand. Treatment of the latter species with (X = CI, Br) AgBF4 led to chloride abstraction and formation of cationic square-planar Co(I) complexes of the type [Co(PCP-iPr)(NO)](+) featuring a linear NO group. This reaction could be viewed as a formal two electron reduction of the metal center by the NO radical from Co(III) to Co(I), if NO is counted as NO+. Hence, these systems can be described as {CoNO}(8) according to the Enemark-Feltham convention. X-ray structures, spectroscopic and electrochemical data of all nitrosyl complexes are presented. Preliminary studies show that [Co(PCPNMe-iPr)(NO)](+) catalyzes efficiently the reductive hydroboration of nitriles with pinacolborane (HBpin) forming an intermediate {CoNO}(8) hydride species.

Computed Properties of C14H11N. Welcome to talk about 86-29-3, If you have any questions, you can contact Pecak, J; Eder, W; Stoger, B; Realista, S; Martinho, PN; Calhorda, MJ; Linert, W; Kirchner, K or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Corsini, E; Facchetti, G; Esposito, S; Maddalon, A; Rimoldi, I; Christodoulou, MS in WILEY-V C H VERLAG GMBH published article about PROTEIN-KINASE-C; IN-VITRO; CANCER; DERIVATIVES; INHIBITORS; RECEPTOR; COMPLEX; MODEL in [Corsini, Emanuela; Esposito, Sara] Univ Milan, Lab Toxicol, Dipartimento Sci Polit & Ambientali, Milan, Italy; [Facchetti, Giorgio; Rimoldi, Isabella; Christodoulou, Michael S.] Univ Milan, DISFARM, Sez Chim Gen & Organ A Marchesini, Via Venezian 21, I-20133 Milan, Italy; [Maddalon, Ambra] Univ Milan, Lab Toxicol, Dipartimento Sci Farmacol & Biomol, Milan, Italy in 2020.0, Cited 38.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In this study, a series of 20 chalcone derivatives was synthesized, and their antiproliferative activity was tested against the human T cell acute lymphoblastic leukemia-derived cell line, CCRF-CEM. On the basis of the structural features of the most active compounds, a new library of chalcone derivatives, according to the structure-activity relationship design, was synthesized, and their antiproliferative activity was tested against the same cancer cell line. Furthermore, four of these derivatives (compounds 3, 4, 8, 28), based on lower IC50 values (between 6.1 and 8.9 mu M), were selected for further investigation regarding the modulation of the protein expression of RACK1 (receptor for activated C kinase), protein kinase C (PKC)alpha and PKC beta, and their action on the cell cycle level. The cell cycle analysis indicated a block in the G0/G1 phase for all four compounds, with a statistically significant decrease in the percentage of cells in the S phase, with no indication of apoptosis (sub-G0/G1 phase). Compounds 4 and 8 showed a statistically significant reduction in the expression of PKC alpha and an increase in PKC beta, which together with the demonstration of an antiproliferative role of PKC beta, as assessed by treating cells with a selective PKC beta activator, indicated that the observed antiproliferative effect is likely to be mediated through PKC beta induction.

Quality Control of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Corsini, E; Facchetti, G; Esposito, S; Maddalon, A; Rimoldi, I; Christodoulou, MS or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem