Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner.In a patent, 2879-20-1, name is 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone, introducing its new discovery. Safety of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone
DMSO is used as a substrate, DMSO is a solvent, three-component one-pot reaction, and aromatic and aliphatic substituted 1, 2, 3 – thiadiazole are obtained under the promotion of cupric chloride and iodide . the invention discloses a preparation method of the aryl and alkyl thiadiazole containing the aryl group and the alkyl thiadiazole by using methyl ketone, p-toluenesulfonyl hydrazide, potassium thiocyanate. The method provided by the invention has very excellent substrate compatibility, especially for the aliphatic substrate, and enriches substrate diversity synthesized 1, 2, 3 – thiadiazole. (by machine translation)
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Safety of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 2879-20-1