22013-33-8, Name is 2,3-Dihydrobenzo[b][1,4]dioxin-6-amine, belongs to benzodioxans compound, is a common compound. COA of Formula: C8H9NO2In an article, once mentioned the new application about 22013-33-8.
Metal-free, ionic liquid-mediated synthesis of functionalized quinolines
An expedient and metal-free synthetic protocol for construction of substituted quinolines has been developed from anilines and phenylacetaldehydes using imidazolium cation-based ionic liquids as the reaction medium. Mechanistic analysis indicated that the reaction occurs through C-C and C-N bond formation to produce isolable 2,3-disubstituted quinoline intermediates, which undergo C-C bond cleavage to produce 3-substituted quinolines. The reaction proceeds smoothly with a range of functionalities in good to excellent yields. Advantages of this protocol include metal-free, environmentally friendly, recyclable reaction media, higher yields and shorter reaction times, and thus is promising for the efficient combinatorial synthesis of structurally diverse 2,3-disubstituted and 3-substituted quinolines.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 22013-33-8
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem