Authors Yang, Y; Yang, Y; Scherpbier, RW; Zhu, X; Chen, Y; Zhou, YB; Jiang, QW in LIPPINCOTT WILLIAMS & WILKINS published article about CHILDHOOD IMMUNIZATION; DISEASE; PREVALENCE; PNEUMONIA; SCHEDULES; PROGRAM; BURDEN in [Yang, Ya; Yang, Yu; Zhou, Yibiao; Jiang, Qingwu] Fudan Univ, Key Lab Publ Hlth Safety, Minist Educ China, Shanghai, Peoples R China; [Yang, Ya; Yang, Yu; Zhou, Yibiao; Jiang, Qingwu] Fudan Univ, Trop Dis Res Ctr, Dept Epidemiol, Sch Publ Hlth, Shanghai, Peoples R China; [Scherpbier, Robert W.; Zhu, Xu] UNICEF Beijing Off, Beijing, Peoples R China; [Chen, Yue] Univ Ottawa, Fac Med, Sch Epidemiol & Publ Hlth, Ottawa, ON, Canada in 2019.0, Cited 59.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6
Background: Use of Haemophilus influenzae type b conjugate vaccine is effective in reducing the disease burden, but its coverage in China is unclear. The aim of this meta-analysis is to assess the coverage of Hib conjugate vaccines in children in Mainland China. Methods: We systematically searched Pubmed, Web of Science, Medline, CNKI and Wanfang to identify studies assessing the coverage of Hib vaccine in Chinese children. Random-effects models were used to obtain pooled estimates for Hib vaccine coverage and analyzed heterogeneity with meta-regression and subgroup analyses. Results: Thirty-three studies that included 7,227,480 subjects in 12 provinces met our inclusion criteria. The pooled overall coverage of Hib conjugate vaccine was 54.9% [95% confidence interval (CI): 52.9-57.0]. The pooled coverage for the nonlocal population (54.3%; 95% CI: 52.4-56.3) was lower than that for the local residents (62.0%; 95% CI: 58.4-65.6). The region-pooled coverage was higher in the east of China (59.7%; 95% CI: 57.3-62.1) than in the central and west parts of the country (48.5%; 95% CI: 40.6-56.4). Overall, 26.7% (95% CI: 20.1-33.2) had 1 dose only, 14.8% (95% CI: 10.0-19.6%) had 2 doses, 13.5% (95% CI: 9.1-17.8) had 3 doses and 14.3% (95% CI: 9.7-18.9) had 4 doses. Conclusions: We found a low coverage of Hib conjugate vaccine, particularly for the nonlocal children and those living in the central and west parts of China. Including Hib vaccine into the national immunization program is recommended to reduce disparities in vaccination coverage.
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Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem