Recently I am researching about BETA-AMINO ALCOHOLS; STEREOSELECTIVE-SYNTHESIS; DIASTEREOSELECTIVE SYNTHESIS; GEM-DIFLUOROALKENES; OXIDATIVE NITRATION; CARBONYL-COMPOUNDS; SCHENCK REACTION; EFFICIENT; CONVERSION; REDUCTION, Saw an article supported by the MEYS CR [LM2015043]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Otevrel, J; Svestka, D; Bobal, P. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile. Application In Synthesis of 2,2-Diphenylacetonitrile
We have identified a novel one-pot method for the synthesis of beta-amino alcohols, which is based on C-H bond hydroxylation at the benzylic alpha-carbon atom with a subsequent nitrile or amide functional group reduction. This cascade process uses molecular oxygen as an oxidant and sodium bis(2-methoxyethoxy)aluminum hydride as a reductant. The substrate scope was examined on 30 entries and, although the respective products were provided in moderate yields only, the above simple protocol may serve as a direct and powerful entry to the sterically congested 1,2-amino alcohols that are difficult to prepare by other routes. The plausible mechanistic rationale for the observed results is given and the reaction was applied to a synthesis of a potentially bioactive target.
Application In Synthesis of 2,2-Diphenylacetonitrile. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem