I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Design, synthesis, and bioevaluation of a novel class of (E)-4-oxocrotonamide derivatives as potent antituberculosis agents published in 2019.0. Computed Properties of C8H7NO3, Reprint Addresses Yu, LY; Wang, JX (corresponding author), Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China.; Yu, LY; Wang, JX (corresponding author), Peking Union Med Coll, Beijing 100050, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
A series of novel (E)-4-oxo-2-crotonamide derivatives were designed and synthesized to find potent antituberculosis agents. All the target compounds were evaluated for their in vitro activity against Mycobacterium tuberculosis H(37)Rv(MTB). Results reveal that 4-phenyl moiety at part A and short methyl group at part C were found to be favorable. Most of the derivatives displayed promising activity against MTB with MIC ranging from 0.125 to 4 mu g/mL. Especially, compound IIIa16 was found to have the best activity with MIC of 0.125 mu g/mL against MTB and with MIC in the range of 0.05-0.48 mu g/mL against drug-resistant clinical MTB isolates.
About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ren, JF; Xu, J; Zhang, GN; Xu, CL; Zhao, LL; You, XF; Wang, YC; Lu, Y; Yu, LY; Wang, JX or concate me.. Computed Properties of C8H7NO3
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Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem