An article Transformations of Aryl Ketones via Ligand-Promoted C-C Bond Activation WOS:000544629400001 published article about CATALYZED DECARBONYLATIVE BORYLATION; CROSS-COUPLING REACTIONS; CLEAVAGE; STRATEGY; EXCHANGE; OXIMES; ETHERS in [Li, Hanyuan; Ma, Biao; Liu, Qi-Sheng; Xu, Hui; Li, Ling-Jun; Wang, Xing; Dai, Hui-Xiong] Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China; [Wang, Mei-Ling] Univ Sci & Technol China, Nano Sci & Technol Inst, Suzhou 215123, Jiangsu, Peoples R China; [Wang, Zhen-Yu] Nanjing Univ Chinese Med, Sch Pharm, Nanjing 210023, Jiangsu, Peoples R China in 2020.0, Cited 77.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6
The coupling of aromatic electrophiles (aryl halides, aryl ethers, aryl acids, aryl nitriles etc.) with nucleophiles is a core methodology for the synthesis of aryl compounds. Transformations of aryl ketones in an analogous manner via carbon-carbon bond activation could greatly expand the toolbox for the synthesis of aryl compounds due to the abundance of aryl ketones. An exploratory study of this approach is typically based on carbon-carbon cleavage triggered by ring-strain release and chelation assistance, and the products are also limited to a specific structural motif. Here we report a ligand-promoted beta-carbon elimination strategy to activate the carbon-carbon bonds, which results in a range of transformations of aryl ketones, leading to useful aryl borates, and also to biaryls, aryl nitriles, and aryl alkenes. The use of a pyridine-oxazoline ligand is crucial for this catalytic transformation. A gram-scale borylation reaction of an aryl ketone via a simple one-pot operation is reported. The potential utility of this strategy is also demonstrated by the late-stage diversification of drug molecules probenecid, adapalene, and desoxyestrone, the fragrance tonalid as well as the natural product apocynin.
About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, HY; Ma, B; Liu, QS; Wang, ML; Wang, ZY; Xu, H; Li, LJ; Wang, X; Dai, HX or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem