Introduction of a new synthetic route about 17413-10-4

With the rapid development of chemical substances, we look forward to future research findings about 17413-10-4

(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)methanamine, cas is 17413-10-4, it is a common heterocyclic compound, the benzodioxans compound, its synthesis route is as follows.

To a solution of fers-butyl (25)-2-{[(6-methoxy-l,5-naphthyridin-4-yl)amino]carbonyl}- 5-oxopiperidine-l -carboxylate (1.19 g) in dichloroethane (50 mL) were added l-(2,3-dihydro- l,4-benzodioxin-6-yl)methanamine (0.60 g) and sodium cyanoborohydride (NaCNBH3) (0.42 g). After stirring at room temperature 60 hours, the reaction was concentrated. This residue was purified by flash chromatography using a FlashMaster using ethylacetate and hexane as eluants yielding 0.45 g of the title compound. ES (M+H)+=550.

With the rapid development of chemical substances, we look forward to future research findings about 17413-10-4

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2006/125974; (2006); A1;,
Benzodioxan
1,4-Benzodioxane | C8H8O2 – PubChem