1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone, cas is 2879-20-1, it is a common heterocyclic compound, the benzodioxans compound, its synthesis route is as follows.
General procedure: A mixture of acetophenone 1a (120 mg, 1.0 mmol), benzylamine 2a (160.7 mg, 1.5 mmol), and iodine (507.6 mg, 2.0 mmol) in DMSO (3 mL) was stirred at 100 C for 5 h. After disappearance of the reactant (monitored by TLC), and added 50 mL water to the mixture, then extracted with EtOAc three times (3 50 mL). The extract was washed with 10% Na2S2O3 solution (w/w), dried over anhydrous Na2SO4 and evaporation. The residue was purified by column chromatography on silica gel (petroleum ether/EtOAc=100:1) to yield the desired product 3aa as a white solid (183.4 mg, 83% yield).
With the rapid development of chemical substances, we look forward to future research findings about 2879-20-1
Reference£º
Article; Gao, Qing-He; Fei, Zhuan; Zhu, Yan-Ping; Lian, Mi; Jia, Feng-Cheng; Liu, Mei-Cai; She, Neng-Fang; Wu, An-Xin; Tetrahedron; vol. 69; 1; (2013); p. 22 – 28;,
Benzodioxan
1,4-Benzodioxane | C8H8O2 – PubChem