Recently I am researching about EFFICIENT SYNTHESIS; O-ALKYNYLANILINES; UNPROTECTED 2-ALKYNYLANILINES; REGIOSELECTIVE SYNTHESIS; 4-QUINOLONE DERIVATIVES; OXIDATIVE CYCLIZATION; CONJUGATE ADDITION; CASCADE REACTIONS; CATALYZED DIRECT; ANNULATION, Saw an article supported by the University of L’Aquila; University La Sapienza, Rome. Category: benzodioxans. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Marsicano, V; Arcadi, A; Chiarini, M; Fabrizi, G; Goggiamani, A; Iazzetti, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
This study describes diversity-oriented synthesis of 2,2,3-substituted-2,3-dihydroquinolin-4(1H)-ones vs. functionalised quinoline or N-alkenylindole derivatives through Bronsted acid mediated or Lewis acid catalyzed sequential reactions of 2-alkynylanilines with ketones. In particular, a series of challenging quinolin-4-one derivatives are prepared with good functional group tolerance in an atom-economical fashion by using p-toluenesulfonic acid monohydrate as a promoter of the reaction of ketones with 2-alkynylanilines in EtOH at reflux, while the same starting materials give the corresponding 4-substituted quinolines in toluene at 110 degrees C both in the presence of p-toluenesulfonic acid monohydrate as the promoter and FeCl3 as the catalyst. The divergent formation of N-alkenylindole derivatives occurs by switching to the use of ZnBr2 as the catalyst under the same reaction conditions. Conversely, only 4-methylsubstituted quinoline derivatives were isolated by reacting 2-ethynylanilines and/or 2-trimethylsylilanilines with ketones in all examined cases.
Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Marsicano, V; Arcadi, A; Chiarini, M; Fabrizi, G; Goggiamani, A; Iazzetti, A or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem