Let¡¯s face it, organic chemistry can seem difficult to learn, Quality Control of 5′-Deoxy-2′,3′-di-O-acetyl-5-fluorocytidine, Especially from a beginner¡¯s point of view. Like 161599-46-8, Name is 5′-Deoxy-2′,3′-di-O-acetyl-5-fluorocytidine, molecular formula is benzodioxans, belongs to benzodioxans compound. In a document, author is WELL, M, introducing its new discovery.
SYNTHESIS AND NMR-SPECTROSCOPY OF PHOSPHORANES WITH 1,3,2-DIOXA-4,5-NAPHTHOPHOSPHOLE RING
The reaction of naphthalene-2,3-diol 1 with PCl3 was found to furnish the hydridophosphorane 3, with PCl5 the chlorophosphorane 4 was formed. The reaction of the fluorophosphoranes, RPF4 [R=F, (i)Pr, CH2SiMe3, CH2Cl, Ph] with the bis(trimethylsilyl) derivative of 1, 2 yielded the corresponding spirocyclic phosphoranes, 5-9 by cleavage of the Si-O bond and elimination of Me3SiF. The difluorophosphoranes, R2PF3 [R=Me, Ph] reacted with 2 to form the monocyclic phosphoranes, 10 and 11, where the fluorine atom occupies an axial position at trigonal-bipyramidal (TBP) phosphorus- The structure of compound 11 was confirmed by single crystal X-ray analysis of its dichloromethane hemisolvate at -95-degrees-C. The geometry at phosphorus is trigonal-bipyramidal. whereby the naphthalenedioxy ligand spans an axial and an equatorial site. Me2PF3 reacted with tetrakis(1,2,4.5-trimethylsiloxy)benzene to form the bifunctional benzodioxa-lambda5-phosphole, 12.
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Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem