Ding, YX; Ma, RC; Hider, RC; Ma, YM in [Ding, Yuxin; Ma, Renchao; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China; [Ding, Yuxin; Ma, Yongmin] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China; [Hider, Robert C.] Kings Coll London, Inst Pharmaceut Sci, Franklin Wilkins Bldg,Stamford St, London SE1 9NH, England published Acid-Catalyzed Pseudo Five-Component Annulation for a General One-Pot Synthesis of 2,4,6-Triaryl Pyrimidines in 2020.0, Cited 65.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.
A facile and general synthesis of 2,4,6-triaryl pyrimidines has been developed. It involves a one-pot [2+1+1+1+1] pseudo five-component annulation of one methyl ketone, two aldehydes and two NH4OAc catalyzed by TfOH. One C-C and four C-N bonds are formed during the oxidative annulation process. The reaction shows good tolerance of many important functional groups in air and produces only water as the coproduct, making this methodology a highly versatile alternative to the existing methods for structuring pyrimidine framework.
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Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem