Extracurricular laboratory: Synthetic route of 1-(4-Nitrophenyl)ethanone

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I found the field of Chemistry very interesting. Saw the article Acetic acid mediated regioselective synthesis of 2,4,5-trisubstituted thiazoles by a domino multicomponent reaction published in 2019.0. Recommanded Product: 100-19-6, Reprint Addresses Khurana, JM (corresponding author), Univ Delhi, Dept Chem, Delhi 110007, India.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Acetic acid mediated regioselective synthesis of novel 2,4,5- trisubstituted thiazole derivatives has been reported by a domino reaction of thiosemicarbazide and aldehydes/ ketones/ isatin, to generate thiosemicarbazones ( in situ) followed by addition of arylglyoxal and active methylene/ activated C- H acids/ pyrazole/ indole in ethanol at 80 1C. The products are obtained in high yields by a simple work up. Metal free, short reaction time and high yields are some merits of this methodology.

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Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem