I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives published in 2020.0. Recommanded Product: 100-19-6, Reprint Addresses Khanye, SD (corresponding author), Rhodes Univ, Fac Sci, Dept Chem, ZA-6140 Grahamstown, South Africa.; Khanye, SD (corresponding author), Rhodes Univ, Ctr Chem & Biomed Res, ZA-6140 Grahamstown, South Africa.; Khanye, SD (corresponding author), Rhodes Univ, Fac Pharm, Div Pharmaceut Chem, ZA-6140 Grahamstown, South Africa.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone
With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in moderate to good yields. The resultant compounds were evaluated in vitro for their potential activity against a cultured Trypanosoma brucei brucei 427 strain. Several compounds displayed mostly modest in vitro anti-trypanosomal activity with compounds 10e and 10h emerging as active candidates with IC50 values of 4.09 and 5.11 mu M, respectively. More importantly, a concomitant assessment of their activity against a human cervix adenocarcinoma (HeLa) cell line revealed that these compounds are non-toxic.
Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zulu, AI; Oderinlo, OO; Kruger, C; Isaacs, M; Hoppe, HC; Smith, VJ; Veale, CGL; Khanye, SD or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem