Category: 65094-22-6

Related Products of 65094-22-6, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, belongs to benzodioxans compound. In a article, author is Dettbarn, WD, introduce new discover of the category.

The contribution of carboxylesterase (CarbE) to toxicity and tolerance to the organophosphorus anticholinesterases; (OP-antiChE) paraoxon (diethyl p-nitrophenyl phosphate) and DFP (diisopropylphosphorofluoridate) was investigated in rats. Daily injections (20 days) of paraoxon (0.33 mu mol/kg) or DFP (2.72 mu mol/kg) reduced AChE activity in brain to 29 or 16% and in diaphragm to 58 or 54%, respectively. The animals tolerated an accumulated 6-fold LD50 dose and survived an LD90 dose of carbachol, indicating tolerance to this cholinergic agonist. A single dose of paraoxon or DFP significantly reduced CarbE activity of plasma, lung and liver. After paraoxon, rapid recovery was seen of plasma and liver CarbE while recovery after DFP was much slower. Daily pretreatment with the CarbE inhibitors CBDP (2-[o-cresyl]-4H-1,2,3-benzodioxa- phosphorin-2-oxide) (7.22 mu mol/kg, s.c.) or iso-OMPA (tetraisopropylpyrophosphoramide) (8.76 mu mol/kg, i.p.), followed by paraoxon (0.33 mu mol/kg, s.c.) 30 min later, prevented the development of tolerance to paraoxon and potentiated its toxicity. Rats died on day four of the combined treatment. The CarbE inhibitors neither potentiated the DFP toxicity, nor prevented tolerance development to DFP. We conclude that rat plasma CarbE provides a significant protection against paraoxon toxicity because its rapid reactivation can reduce the toxicity of repeated paraoxon applications and thus contribute to tolerance development. This same mechanism does not apply to DFP toxicity, as inhibition of CarbE of plasma, liver and lung neither potentiated its toxicity, nor prevented tolerance development. These findings confirm previous observations that CarbE detoxification is of greater importance for highly toxic OP-antiChEs such as nerve agents and paraoxon than for less toxic ones such as DFP. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

Related Products of 65094-22-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application of 65094-22-6, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, belongs to benzodioxans compound. In a article, author is Bilgin, Ahmet, introduce new discover of the category.

Novel maleonitrile moieties were synthesized by cyclization of 2,3-bis[(2-pyridylmethyl)amino]-2(Z)-butene-1,4-dinitrile with 1,2-bis(2-iodoethoxy)-4-nitrobenzene or o-xylyenebis(1-chloro-3-thiapropane) under conditions of high dilution. A series of novel, free-base, magnesium and zinc porphyrazines bearing macrocyclic substituents in peripheral positions were prepared via Linstead macrocyclization reactions of different maleonitrile derivatives, 12-nitro-4,7-bis(pyridin-2-ylmethyl)-2,3,4,7,8,9-hexahydro-1,10,4,7-benzodioxa-diaza-cyclododecine-5,6-dicarbonitrile or 5,8-bis(pyridin-2-ylmethyl)-1,3,4,5,8, 9,10,12-octa-hydro-2,11,5,8-benzodi-thiadiazacyclo-tetradecine-6,7-dicarbonitrile and the corresponding divalent metal salts. Pentanuclear copper(II) complexes were also prepared from the corresponding zinc(II) porphyrazine derivatives. The compounds were characterized by a combination of elemental analysis, FT-IR, UV-vis, H-1 NMR, C-13 NMR and MS spectral data. (c) 2008 Elsevier Ltd. All rights reserved.

Application of 65094-22-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

A selective and sensitive method for the preconcentration, separation, and determination of palladium with flame atomic absorption spectrometry using 4,15-bis[(4-methylphenyl)sulfonyl]-20,21-dinitro-2,3,4,5,6,7,9,10,12,13,14,15,16,17-tetradecahydro- 8,11-ethano-1,18,4,8,11,15-benzodioxa tetraaza cycloicosine (TNACIN) on XAD-2010 was developed. TNACIN-Pd(II) complex formed acidic aqueous solution (0.075-0.100 M HNO3) was accumulated on XAD-2010 and then eluted with 1 M HCl in acetone. The effects of some analytical parameters including pH, TNACIN amount, sample volume, eluent type, and concentration, sample flow rate and matrix ions were studied for optimization of the method. Detection limit and precision were calculated for Pd(II). This method was also verified with CRM and internal standard, and satisfactory results were obtained.

If you are hungry for even more, make sure to check my other article about 65094-22-6, Application In Synthesis of Diethyl (bromodifluoromethyl)phosphonate.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, in an article , author is Mironov, Vladimir F., once mentioned of 65094-22-6, Recommanded Product: Diethyl (bromodifluoromethyl)phosphonate.

The reaction of 4-(1,3,2-benzodioxaphosphol-2-yloxy)-3-tert-butylpent-4-en-2-one with hexafluoroacetone

Catalytic (ZnCl2, Et3N) phosphorylation of tert-butylacetyl-acetone with 2-chloro-1,3,2-benzodioxaphosphole unexpectedly occurs with elimination of proton from the methyl group and leads to vinyloxyphosphole derivative, viz., 4-(1,3,2-benzodioxa-phosphol-2-yloxy)-3-tert-butylpent-4-en-2-one. Its reaction with hexafluoroacetone gives a cage phosphorane as a result of subsequent chemoselective[4+2]- and [3 + 2]-cyclo-additions with stereoselectivity above 95%.

Interested yet? Read on for other articles about 65094-22-6, you can contact me at any time and look forward to more communication. Recommanded Product: Diethyl (bromodifluoromethyl)phosphonate.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Name: Diethyl (bromodifluoromethyl)phosphonate, 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, belongs to benzodioxans compound. In a document, author is Ali, HM, introduce the new discover.

Selectivity, acetylcholinesterase inhibition kinetics, and quantitative structure-activity relationships of a series of N-(2-oxido-1,3,2-benzodioxa-phosphol-2-yl) amino acid ethyl or diethyl esters

The inhibitory effects of a recently introduced series of the titled compounds on insect and mammalian acetylcholinesterase (AChE) activity were examined, where the median inhibition concentration (I-50) and the inhibition kinetic parameters, bimolecular inhibition rate constant (k(i)), affinity constant (K-a), and phosphorylation rate constant (k(p)), were determined for each compound. Results indicated that all examined dioxaphospholenes had less inhibitory effects on mammalian AChE than fenitrothion, a commercial pesticide with moderate mammalian toxicity. The highest selectivity was obtained with compounds containing glutamic and leucine moieties (2.70 and 2.18, respectively) while selectivity of fenitrothion was 0.93. The low inhibitory effects of the examined dioxaphospholenes on mammalian AChE were attributed to their low phosphorylation rates(k(p) < 2.2 min(-1)) compared to that of fenitrothion (k(p) = 4.84 min(-1)). QSAR equations indicated that the inhibition process is controlled mainly by both the phosphorylation rate (direct effect) and the affinity of compounds toward the enzyme (inverse effect). Although the compounds' hydrophobicity had no effects on the inhibition process, it affects the compounds' toxicity since it affects the ability of compounds to penetrate insects to reach the enzyme active site. (c) 2005 Elsevier Inc. All rights reserved. A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 65094-22-6. Name: Diethyl (bromodifluoromethyl)phosphonate.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Electric Literature of 65094-22-6, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, belongs to benzodioxans compound. In a article, author is Dettbarn, WD, introduce new discover of the category.

Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP

The contribution of carboxylesterase (CarbE) to toxicity and tolerance to the organophosphorus anticholinesterases; (OP-antiChE) paraoxon (diethyl p-nitrophenyl phosphate) and DFP (diisopropylphosphorofluoridate) was investigated in rats. Daily injections (20 days) of paraoxon (0.33 mu mol/kg) or DFP (2.72 mu mol/kg) reduced AChE activity in brain to 29 or 16% and in diaphragm to 58 or 54%, respectively. The animals tolerated an accumulated 6-fold LD50 dose and survived an LD90 dose of carbachol, indicating tolerance to this cholinergic agonist. A single dose of paraoxon or DFP significantly reduced CarbE activity of plasma, lung and liver. After paraoxon, rapid recovery was seen of plasma and liver CarbE while recovery after DFP was much slower. Daily pretreatment with the CarbE inhibitors CBDP (2-[o-cresyl]-4H-1,2,3-benzodioxa- phosphorin-2-oxide) (7.22 mu mol/kg, s.c.) or iso-OMPA (tetraisopropylpyrophosphoramide) (8.76 mu mol/kg, i.p.), followed by paraoxon (0.33 mu mol/kg, s.c.) 30 min later, prevented the development of tolerance to paraoxon and potentiated its toxicity. Rats died on day four of the combined treatment. The CarbE inhibitors neither potentiated the DFP toxicity, nor prevented tolerance development to DFP. We conclude that rat plasma CarbE provides a significant protection against paraoxon toxicity because its rapid reactivation can reduce the toxicity of repeated paraoxon applications and thus contribute to tolerance development. This same mechanism does not apply to DFP toxicity, as inhibition of CarbE of plasma, liver and lung neither potentiated its toxicity, nor prevented tolerance development. These findings confirm previous observations that CarbE detoxification is of greater importance for highly toxic OP-antiChEs such as nerve agents and paraoxon than for less toxic ones such as DFP. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

Electric Literature of 65094-22-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Related Products of 65094-22-6, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, SMILES is CCOP(=O)(OCC)C(F)(F)Br, belongs to benzodioxans compound. In a article, author is Bilgin, Ahmet, introduce new discover of the category.

Novel porphyrazines containing peripherally functionalized macrocyclic (N2O2, N2S2) units: Synthesis and characterization

Novel maleonitrile moieties were synthesized by cyclization of 2,3-bis[(2-pyridylmethyl)amino]-2(Z)-butene-1,4-dinitrile with 1,2-bis(2-iodoethoxy)-4-nitrobenzene or o-xylyenebis(1-chloro-3-thiapropane) under conditions of high dilution. A series of novel, free-base, magnesium and zinc porphyrazines bearing macrocyclic substituents in peripheral positions were prepared via Linstead macrocyclization reactions of different maleonitrile derivatives, 12-nitro-4,7-bis(pyridin-2-ylmethyl)-2,3,4,7,8,9-hexahydro-1,10,4,7-benzodioxa-diaza-cyclododecine-5,6-dicarbonitrile or 5,8-bis(pyridin-2-ylmethyl)-1,3,4,5,8, 9,10,12-octa-hydro-2,11,5,8-benzodi-thiadiazacyclo-tetradecine-6,7-dicarbonitrile and the corresponding divalent metal salts. Pentanuclear copper(II) complexes were also prepared from the corresponding zinc(II) porphyrazine derivatives. The compounds were characterized by a combination of elemental analysis, FT-IR, UV-vis, H-1 NMR, C-13 NMR and MS spectral data. (c) 2008 Elsevier Ltd. All rights reserved.

Related Products of 65094-22-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, molecular formula is C5H10BrF2O3P. In an article, author is Keglevich, Gyoergy,once mentioned of 65094-22-6, Recommanded Product: 65094-22-6.

Platinum Complexes of Five- and Six-Membered P-Heterocycles as Potential Catalysts

5- and 6-Membered P-heterocycles including phosphines (1H-phospholes, 3-phospholenes, phospholanes, dihydro-and tetrahydrophosphinines), phosphinites (dibenzo[c. e][1,2]oxaphosphorines) and phosphonites (benzo[1,3,2]dioxaphospholanes), as well as, 3-P-substituted species 3-diphenylphosphino-1,2,3,6-tetrahydrophosphinine or 1,2,3,4,5,6-hexahydrophosphinine derivatives are surveyed as potential monodentate and bidentate P(III)-ligands in platinum(II)-complexes. The cis structures were assigned on the basis of stereospecific (1)J(P-31-Pt-195) NMR coupling constants. The catalytic effect of selected Pt(II)-complexes in hydroformylation is also summarized.

Interested yet? Keep reading other articles of 65094-22-6, you can contact me at any time and look forward to more communication. Recommanded Product: 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Let¡¯s face it, organic chemistry can seem difficult to learn, Product Details of 65094-22-6, Especially from a beginner¡¯s point of view. Like 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, molecular formula is C19H20N2O2, belongs to pyrazoles-derivatives compound. In a document, author is Bulut, Volkan Numan, introducing its new discovery.

Selective Solid Phase Extraction for Separation and Preconcentration of Palladium from Gold Ore and Anode Slime after Complexation with a N4O2 Mixed Donor Ligand Derivative

A selective and sensitive method for the preconcentration, separation, and determination of palladium with flame atomic absorption spectrometry using 4,15-bis[(4-methylphenyl)sulfonyl]-20,21-dinitro-2,3,4,5,6,7,9,10,12,13,14,15,16,17-tetradecahydro- 8,11-ethano-1,18,4,8,11,15-benzodioxa tetraaza cycloicosine (TNACIN) on XAD-2010 was developed. TNACIN-Pd(II) complex formed acidic aqueous solution (0.075-0.100 M HNO3) was accumulated on XAD-2010 and then eluted with 1 M HCl in acetone. The effects of some analytical parameters including pH, TNACIN amount, sample volume, eluent type, and concentration, sample flow rate and matrix ions were studied for optimization of the method. Detection limit and precision were calculated for Pd(II). This method was also verified with CRM and internal standard, and satisfactory results were obtained.

If you are hungry for even more, make sure to check my other article about 65094-22-6, Product Details of 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Chemistry is an experimental science, SDS of cas: 65094-22-6, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 65094-22-6, Name is Diethyl (bromodifluoromethyl)phosphonate, molecular formula is C5H10BrF2O3P, belongs to benzodioxans compound. In a document, author is LUNDMARK, S.

KINETICS, MECHANISMS, AND SYNTHESIS STUDIES OF RING-OPENING-CLOSING ALTERNATING COPOLYMERIZATION

The present paper describes the ring-opening-closing alternating copolymerization of cyclic phosphonites (2-phenyl-1,3,2-dioxaphospholane (1a), 2-phenyl-1,3,2-dioxaphosphorinane(1b), 2-phenyl-1,3,2-dioxaphosphepane(1c), and 2-phenyl-4H-1,3,2-benzodioxa phosphorin-4-one(1d) with muconic acid(2a), succinaldehyde(2b), glutaraldehyde(2c), adipinaldehyde(2d), o-phthalaldehyde(2e), acrylic anhydride(2f), methacrylic anhydride(2g), N-methyl diacrylamide(2h), and N-methyldimethacrylamide(2i). The reaction of a 1:1 monomer feed ratio, explained by a mechanism of propagation via zwitterion intermediates, proceeds without any added catalyst to give an alternating copolymer 3 involving ring-opening of 1 and ring-closing of 2. The structure of copolymer 3 was determined by H-1, C-13 NMR, P-31 NMR and IR spectroscopies as well as elemental analysis.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 65094-22-6. SDS of cas: 65094-22-6.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem