Category: 10288-72-9

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 10288-72-9, In a patent£¬Which mentioned a new discovery about 10288-72-9

PROTEIN KINASE INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH

The invention relates to MKK4 (mitogen-activated protein kinase 4) and their use in promoting liver regeneration or reducing or preventing hepatocyte death. The MKK4 inhibitors selectively inhibit protein kinase MKK4 over protein kinases JNK and MKK7.

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Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

10288-72-9, In an article, published in an article,authors is Campbell, Michael G., once mentioned the application of 10288-72-9, Name is 6-Hydroxy-1,4-benzodioxane,molecular formula is C8H8O3, is a conventional compound. this article was the specific content is as follows.

Bimetallic photoredox catalysis: Visible light-promoted aerobic hydroxylation of arylboronic acids with a dirhodium(ii) catalyst

We report the use of a rhodium(II) dimer in visible light photoredox catalysis for the aerobic oxidation of arylboronic acids to phenols under mild conditions. Spectroscopic and computational studies indicate that the catalyst Rh2(bpy)2(OAc)4 (1) undergoes metal-metal to ligand charge transfer upon visible light irradiation, which is responsible for catalytic activity. Further reactivity studies demonstrate that 1 is a general photoredox catalyst for diverse oxidation reactions.

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Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

10288-72-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 10288-72-9, Name is 6-Hydroxy-1,4-benzodioxane, molecular formula is C8H8O3. In a Article, authors is Musso, Loana£¬once mentioned of 10288-72-9

Synthesis and antifungal activity of 2-hydroxy-4,5-methylenedioxyaryl ketones as analogues of kakuol

In a study aiming to determine the structural elements essential to the antifungal activity of kakuol, we synthesized a series of 2-hydroxy-4,5- methylenedioxyaryl ketones, and we assayed their in vitro antifungal activity. The most sensitive target organisms to the action of these class of compounds were Phytophthora infestans, Phytium ultimum, Cercospora beticola, Cladosporium cucumerinum, and Rhizoctonia solani. Most of the analogs showed a remarkable in vitro activity, and some of them appeared significantly more effective than the natural product. The biological activity was mainly affected by introducing structural modification on the carbonyl moiety of the natural-product molecule. In particular, compound 5a, bearing a C=C bond conjugated to the C=O group, was found active with a MIC value of 10 mug ml-1 against Cladosporium cucumerinum. The results suggest that 2-hydroxy-4,5-methylenedioxyaryl ketones can be considered promising candidates in the development of new antifungal compounds.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 10288-72-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10288-72-9, in my other articles.

Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem