Category: 100-19-6

An article Highly Selective Hydroboration of Carbonyls by a Manganese Catalyst: Insight into the Reaction Mechanism WOS:000576677500011 published article about ASYMMETRIC REDUCTION; EFFICIENT CATALYST; KETONES; ALDEHYDES; HYDROSILYLATION; COMPLEXES; HYDRIDE; RUTHENIUM; POLY(SILYLETHER)S; HYDROGENATION in [Vijjamarri, Srikanth; O’Denius, Timothy M.; Yao, Bin; Kubatov, Alena; Du, Guodong] Univ North Dakota, Dept Chem, Grand Forks, ND 58202 USA in 2020.0, Cited 81.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

Hydroboration of carbonyl compounds is an important transformation in organic chemistry, and a growing interest in catalysis has focused on abundant and nontoxic base metals. Herein we describe an efficient salen manganese catalyst for the hydroboration of a broad range of carbonyl compounds with pinacolborane. The catalytic reactions proceeded rapidly (>99% conversion in <5 min) at room temperature with very low catalyst loadings. High turnover frequency (up to 5700 h(-1)) was observed under these conditions. Several synthetically important functional groups were tolerated, and chemoselective hydroboration of aldehydes over ketones was achieved. The H/D kinetic isotopic effect of borane was determined to be 2.3. The Hammett correlation plot of a series of para-substituted acetophenone substrates, p-X-C6H6COCH3 (X = H, Me, OMe, NO2, Cl, Br, and CF3) yielded a positive slope of rho = +0.99. The crossover products were detected in the competition reaction of catecholborane and deuterated pinacolborane with acetophenone. The findings indicated a potential borane-mediated pathway that could account for the observation of the crossover products. Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Vijjamarri, S; O’Denius, TM; Yao, B; Kubatov, A; Du, GD or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Schroeder, S; Strauch, C; Gaelings, N; Niggemann, M in [Schroeder, Sebastian; Strauch, Christina; Gaelings, Niklas; Niggemann, Meike] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52072 Aachen, Germany published Vinyl Triflimides-A Case of Assisted Vinyl Cation Formation in 2019.0, Cited 56.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A new concept for selectivity control in carbocation-driven reactions has been identified which allows for the chemo-, regio-, and stereoselective addition of nucleophiles to alkynes-assisted vinyl cation formation-enabled by a Li+-based supramolecular framework. Mechanistic analysis of a model complex (Li2NTf2+center dot 3H(2)O) confirms that solely the formation of a complex between the incoming nucleophile and the transition state of the alkyne protonation is responsible for the resulting selective Naddition to the vinyl cation. Into the bargain, a general, operationally simple synthetic procedure to previously inaccessible vinyl triflimides is provided.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Schroeder, S; Strauch, C; Gaelings, N; Niggemann, M or concate me.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. In 2020 ANGEW CHEM INT EDIT published article about SELECTIVE HYDROGENATION; REDUCTION; BENZIMIDAZOLES; NANOPARTICLES; DERIVATIVES; DISCOVERY; AFFINITY; IMINES; POTENT; AGENTS in [Ryabchuk, Pavel; Leischner, Thomas; Kreyenschulte, Carsten; Spannenberg, Anke; Junge, Kathrin; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany in 2020, Cited 50. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A bifunctional 3d-metal catalyst for the cascade synthesis of diverse pyrroles from nitroarenes is presented. The optimal catalytic system Co/NGr-C@SiO2-L is obtained by pyrolysis of a cobalt-impregnated composite followed by subsequent selective leaching. In the presence of this material, (transfer) hydrogenation of easily available nitroarenes and subsequent Paal-Knorr/Clauson-Kass condensation provides >40 pyrroles in good to high yields using dihydrogen, formic acid, or a CO/H2O mixture (WGSR conditions) as reductant. In addition to the favorable step economy, this straightforward domino process does not require any solvents or external co-catalysts. The general synthetic utility of this methodology was demonstrated on a variety of functionalized substrates including the preparation of biologically active and pharmaceutically relevant compounds, for example, (+)-Isamoltane.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ryabchuk, P; Leischner, T; Kreyenschulte, C; Spannenberg, A; Junge, K; Beller, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. In 2021.0 J ORG CHEM published article about DIMETHYL-SULFOXIDE; AMINOOXYGENATION; 2-AMINOPYRIDINES; DERIVATIVES; IMIDAZO; KETONES; ALKYNES; ACCESS in [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Inst Adv Studies, Taizhou 318000, Peoples R China; [Zhang, Yi; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China; [Zhang, Yi; Ma, Yongmin] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China in 2021.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A convenient one-pot, three-component reaction has been developed for the synthesis of 3-aroylimidazo[1,2-a]-N-hetero-cycles from aryl ketones and 2-amino-N-heterocycles using dimethyl sulfoxide as a methylene donor. The reaction proceeds smoothly catalyzed by I-2 in the presence of K2S2O8 and affords the desired products in moderate to good yields. This protocol offers significant superiority in accessing biologically active 3-aroylimidazo[1,2-a]-N-heterocycles with various substitution patterns.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, Y; Chen, RE; Wang, ZM; Wang, L; Ma, YM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M in [Massolo, Elisabetta; Pirola, Margherita; Puglisi, Alessandra; Rossi, Sergio; Benaglia, Maurizio] Univ Milan, Dipartimento Chim, Via Golgi 19, I-20133 Milan, Italy published A one pot protocol to convert nitro-arenes into N-aryl amides in 2020, Cited 42. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A two-step one pot, experimentally simple protocol, based on readily available and inexpensive reagents allowed the conversion of nitro-arenes directly to N-aryl amides. A metal-free reduction of the nitro group, mediated by trichlorosilane, followed by the addition of an anhydride afforded the corresponding N-aryl carboxyamide, that was isolated after a simple aqueous work up in good-excellent yields. When the methodology was applied to the reaction with gamma-butyrolactone, the desired N-aryl butanamide derivative was obtained, featuring a chlorine atom at the gamma-position, a functionalized handle that can be used for further synthetic manipulation of the reaction product. Such an intermediate has already been employed as a key advanced precursor of pharmaceutically active compounds.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M or concate me.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. Authors Mar’yasov, MA; Kayukov, YS; Nasakin, OE in SPRINGER published article about in [Mar’yasov, M. A.; Kayukov, Ya S.; Nasakin, O. E.] IN Ulyanov Chuvash State Univ, Cheboksary 428010, Russia in 2020.0, Cited 12.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The influence of previously synthesized 2-aroyl-1,1,3,3-tetracyanoprop-2-en-1-ides on the growth of conditionally normal and tumor cells was studied in continuation of a search for new anticancer drugs. Cytotoxicities of the compounds were studied with respect to human tumor cell lines from the ATCC. All compounds were ineffective against melanoma and lung and ovary cancer cell lines and exhibited moderate activity in the other cases. The tested compounds exhibited highly selective effects because they were safe for conditionally normal skin fibroblasts.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Mar’yasov, MA; Kayukov, YS; Nasakin, OE or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation WOS:000496896600053 published article about SELECTIVE INHIBITORS; DERIVATIVES; DESIGN; POTENT; DISCOVERY; DOCKING; HYBRIDS; MOIETY; AGENTS in [Moi, Davide; Balboni, Gianfranco; Onnis, Valentina] Univ Cagliari, Unit Pharmaceut Pharmacol & Nutraceut Sci, Dept Life & Environm Sci, Via Osped 72, I-09124 Cagliari, Italy; [Nocentini, Alessio; Supuran, Claudiu T.] Univ Firenze, Pharmaceut & Nutraceut Sect, Dept NEUROFARBA, Via Ugo Schiff 6, I-50019 Florence, Italy; [Deplano, Alessandro] Pharmacelera, Placa Pau Vila 1,Sect 1,Edificio Palau Mar, Barcelona 08039, Spain in 2019.0, Cited 64.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Quality Control of 1-(4-Nitrophenyl)ethanone

Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), hCA I, II, IX, and XII. The reported derivatives, obtained by a sulfamoylation reaction of the corresponding phenolic precursors, bear 3,5-diarylpyrazoline moieties as spacers between the benzenesulfamate fragment which binds the zinc ion from the active site, and the tail of the inhibitor. Pyrazolines are biologically privileged scaffolds, endowed with versatile biological activity, such as an anti-proliferative action. The derivatives were tested for the inhibition of the cytosolic, hCA I and II (off target isoforms) and the trans-membrane, tumor-associated hCA IX and XII enzymes (anticancer drug targets). Generally, hCA I was not effectively inhibited, whereas many low nanomolar inhibitors were evidenced against hCA II (KIs in the range of 0.42-90.1 nM), IX (KIs in the range of 0.72-63.6 nM), and XII (KIs in the range of 0.88-85.2 nM). The best substitution fragments at the pyrazoline ring included for CA it a 4-sulfamic group on the 3-aryl and halogens on the 5-aryl or a methoxy group on the 3-aryl and a 4-sulfamate group on the 5-aryl; for CA IX and CA XII they included the sulfamic group on the 3- or 4-position of the 5-aryl and an electronwithdrawing group on the 4-postion of the 3-aryl ring. (C) 2019 Elsevier Masson SAS. All rights reserved.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Moi, D; Nocentini, A; Deplano, A; Balboni, G; Supuran, CT; Onnis, V or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Ma, RC; Ding, YX; Chen, R; Wang, ZM; Wang, L; Ma, YM in [Ma, Renchao; Ding, Yuxin; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Inst Adv Studies, Taizhou 318000, Peoples R China; [Ma, Renchao; Ding, Yuxin; Chen, Rener; Wang, Zhiming; Wang, Lei; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China published Oxidant/Solvent-Controlled I-2-Catalyzed Domino Annulation for Selective Synthesis of 2-Aroylbenzothiazoles and 2-Arylbenzothiazoles under Metal-Free Conditions in 2021.0, Cited 68.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A simple and practical domino protocol for the selective synthesis of 2-aroylbenzothiazoles and 2-aryl benzothiazoles catalyzed by I-2 is developed under metal-free conditions. The reaction outcomes are exclusively controlled by the reaction oxidant/medium. With DMSO employed as both the solvent and the oxidant, an oxidation of aromatic methyl ketones takes precedence over the condensation with 2-aminobenzenethiols. On the other hand, when the reaction was carried out in PhNO2 or in 1,4-dioxane containing PhNO2, the condensation of aromatic methyl ketones with 2-aminobenzenethiols has priority to form imines which is followed by an oxidation of the methyl group from ketones to afford 2-arylbenzothiazoles as a sole product. The PhNO2/I-2 co-catalytic system is proposed first time.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ma, RC; Ding, YX; Chen, R; Wang, ZM; Wang, L; Ma, YM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Badran, I; Tighadouini, S; Radi, S; Zarrouk, A; Warad, I in ELSEVIER published article about in [Badran, Ismail; Warad, Ismail] Qatar Univ, Dept Chem & Earth Sci, POB 2713, Doha, Qatar; [Tighadouini, Said] Hassan II Univ, Fac Sci Ain Chock, Lab Organ Synth Extract & Valorizat, Route Jadida Km 2,BP 5366, Casablanca, Morocco; [Radi, Smaail] Mohammed First Univ, Lab Appl & Environm Chem LCAE, Oujda, Morocco; [Zarrouk, Abdelkader] Mohammed V Univ, Fac Sci, Lab Mat Nanotechnol & Environm, Av I Bn Battouta,Box 1014, Rabat, Morocco in 2021.0, Cited 57.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Hydrazine derivatives have a wide variety of applications in organic synthesis, material science, medical treatments, as well as the dye-sensitized solar cells (DSSC). In this work, the molecular structure, electronic spectra and first principles investigation for the exo-endo isomerization in (1E,2E)-bis[1-(4-nitrophenyl)ethylidene]hydrazine were studied. The structural interactions and synthon formations have been determined experimentally via Hirshfeld surface analysis (HSA) and two-dimensional fingerprint plots (2D-FP). Furthermore, the solid-state XRD/HSA interactions have been used to explain the physical behavior of the compound. The transition state for the exo-endo isomerization was located using density functional theory (DFT). The activation barrier is estimated to be 110.5 kJ/mol (in vacuo). The endo isomer was found to be slightly more stable than the exo one. The UV-Vis spectra of the two isomers were obtained using time-dependent density functional theory (TDDFT) and compared to the experimental spectra in vacuo, water, and methanol. To explore the potential of the new compound as a DSSC sensitizer, the emission spectrum was also constructed by optimizing the singlet electronic excited state. (C) 2020 The Author(s). Published by Elsevier B.V.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Badran, I; Tighadouini, S; Radi, S; Zarrouk, A; Warad, I or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Recently I am researching about BIOLOGICAL EVALUATION; 1,1-DIARYLETHYLENES; TOSYLHYDRAZONES, Saw an article supported by the CNRS, Univ. Paris-SudCentre National de la Recherche Scientifique (CNRS); La Ligue Nationale Contre le Cancer through an Equipe Labellisee 2014 grant; Agence Nationale de la RechercheFrench National Research Agency (ANR)European Commission [ANR-10-LABX-33]; Ministere de l’Enseignement Superieur, de la Recherche et de l’Innovation (MESRI). Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lamaa, D; Messe, E; Gandon, V; Alami, M; Hamze, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A green Barluenga-Valdes cross-coupling reaction for the synthesis of 1,1-diarylethylenes using palladium catalysis has been developed. The new catalytic system based on Pd/Xphos-SO3Na or Pd/MeDavephos-CF3SO3 in PEG/H2O under microwave irradiation was found to be the best conditions for this transformation. The recyclability of the palladium catalyst system was also studied, and it was found to be active over nine runs without significant loss in its activity.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Lamaa, D; Messe, E; Gandon, V; Alami, M; Hamze, A or concate me.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem