Category: 100-19-6

Name: 1-(4-Nitrophenyl)ethanone. In 2020 ANGEW CHEM INT EDIT published article about SELECTIVE HYDROGENATION; REDUCTION; BENZIMIDAZOLES; NANOPARTICLES; DERIVATIVES; DISCOVERY; AFFINITY; IMINES; POTENT; AGENTS in [Ryabchuk, Pavel; Leischner, Thomas; Kreyenschulte, Carsten; Spannenberg, Anke; Junge, Kathrin; Beller, Matthias] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany in 2020, Cited 50. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A bifunctional 3d-metal catalyst for the cascade synthesis of diverse pyrroles from nitroarenes is presented. The optimal catalytic system Co/NGr-C@SiO2-L is obtained by pyrolysis of a cobalt-impregnated composite followed by subsequent selective leaching. In the presence of this material, (transfer) hydrogenation of easily available nitroarenes and subsequent Paal-Knorr/Clauson-Kass condensation provides >40 pyrroles in good to high yields using dihydrogen, formic acid, or a CO/H2O mixture (WGSR conditions) as reductant. In addition to the favorable step economy, this straightforward domino process does not require any solvents or external co-catalysts. The general synthetic utility of this methodology was demonstrated on a variety of functionalized substrates including the preparation of biologically active and pharmaceutically relevant compounds, for example, (+)-Isamoltane.

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ryabchuk, P; Leischner, T; Kreyenschulte, C; Spannenberg, A; Junge, K; Beller, M or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Wei, ZY; Ru, S; Zhao, QX; Yu, H; Zhang, G; Wei, YG in [Wei, Zheyu; Ru, Shi; Zhao, Qixin; Yu, Han] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China; [Yu, Han; Wei, Yongge] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China; [Zhang, Gang] Sichuan Univ, Inst Mat Sci & Technol, Chengdu 610064, Sichuan, Peoples R China; [Zhang, Gang] Sichuan Univ, Analyt & Testing Ctr, Chengdu 610064, Sichuan, Peoples R China published Highly efficient and practical aerobic oxidation of alcohols by inorganic-ligand supported copper catalysis in 2019.0, Cited 66.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The oxidation of alcohols to aldehydes or ketones is a highly relevant conversion for the pharmaceutical and fine-chemical industries, and for biomass conversion, and is commonly performed using stoichiometric amounts of highly hazardous oxidants. The aerobic oxidation of alcohols with transition metal complex catalysts previously required complicated organic ligands and/or nitroxyl radicals as co-catalysts. Herein, we report an efficient and eco-friendly method to promote the aerobic oxidation of alcohols using an inorganic-ligand supported copper catalyst 1, (NH4)(4)[CuMo6O18(OH)(6)], with O-2 (1 atm) as the sole oxidant. Catalyst 1 is synthesized directly from cheap and commonly available (NH4)(6)Mo7O24 center dot 4H(2)O and CuSO4, which consists of a pure inorganic framework built from a central Cu-II core supported by six (MoO6)-O-VI inorganic scaffolds. The copper catalyst 1 exhibits excellent selectivity and activity towards a wide range of substrates in the catalytic oxidation of alcohols, and can avoid the use of toxic oxidants, nitroxyl radicals, and potentially air/moisture sensitive and complicated organic ligands that are not commercially available. Owing to its robust inorganic framework, catalyst 1 shows good stability and reusability, and the catalytic oxidation of alcohols with catalyst 1 could be readily scaled up to gram scale with little loss of catalytic activity, demonstrating great potential of the inorganic-ligand supported Cu catalysts in catalytic chemical transformations.

Application In Synthesis of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wei, ZY; Ru, S; Zhao, QX; Yu, H; Zhang, G; Wei, YG or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 BIOORG CHEM published article about PROLIFERATOR-ACTIVATED RECEPTORS; CYCLOOXYGENASE-2 INHIBITORS; MOLECULAR DOCKING; INFLAMMATION; GLUCOSIDASE; REGULATOR; DISCOVERY; ANALOGS; RAT in [Abdellatif, Khaled R. A.; Fadaly, Wael A. A.] Beni Suef Univ, Fac Pharm, Pharmaceut Organ Chem Dept, Bani Suwayf, Egypt; [Abdellatif, Khaled R. A.] Ibn Sina Natl Coll Med Studies, Pharmaceut Sci Dept, Jeddah 21418, Saudi Arabia; [Kamel, Gehan M.] Cairo Univ, Fac Vet, Pharmacol Dept, Cairo, Egypt; [Elshaier, Yaseen A. M. M.] Al Azhar Univ, Pharmaceut Organ Chem Dept, Fac Pharm, Assiut 71524, Egypt; [El-Magd, Mohammed A.] Kafrelshiekh Univ, Anat Dept, Fac Vet Med, Kafrelshiekh 33516, Egypt in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Nowadays, diabetes and its associated inflammatory complications are important public health problems worldwide. Market limitations of drugs with dual actions as anti-inflammatory (AI) and anti-diabetic have been led to a temptation for focusing on the discovery and development of new compounds with potential AI and antidiabetic activities. Herein, we synthesized two new series containing pyrazole ring with vicinal diaryl rings as selective COX-2 moiety and thiazolidindione (series 12a-f) or thiazolidinone (series 13a-f) as anti-diabetic moiety and the two moieties were linked together with methylene or methylenehydrazone functionality. The two series were evaluated for their COX inhibition, AI activity and ulcerogenic liability and for the anti-diabetic activity; 12a-f and 13a-f were assessed in vitro against alpha-glucosidase, beta-glucosidase, in vivo hypoglycemic activity (one day and 15 days studies) in addition to PPAR. activation study. Four compounds (12c, 12f, 13b and 13f) had higher COX-2 S.I. (8.69-9.26) than the COX-2 selective drug celecoxib (COX-2 S.I. = 8.60) and showed the highest AI activities and the lowest ulcerogenicity than other derivatives. Also, two thiazolidindione derivatives 12e and 12f and two thiazolidinone derivatives 13b and 13c showed higher inhibitory activities against alpha- and beta-glucosidase (% inhibitory activity = 62.15, 55.30, 65.37, 59.08 for alpha-glucosidase and 57.42, 60.07, 58.19, 66.90 for beta-glucosidase respectively) than reference compounds (acarbose with % inhibitory activity = 49.50 for alpha-glucosidase and D-saccharic acid 1,4-lactone monohydrate with % inhibitory activity = 53.42 for beta-glucosidase) and also showed good PPAR-gamma activation and good hypoglycemic effect in comparison to pioglitazone and rosiglitazone. Moreover, Shape comparison and docking studies were carried out to understand their interaction and similarity with standard drugs.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Abdellatif, KRA; Fadaly, WAA; Kamel, GM; Elshaier, YAMM; El-Magd, MA or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. Choi, S; Oh, H; Sim, J; Yu, E; Shin, S; Park, CM in [Choi, Subin; Oh, Hyeonji; Sim, Jeongwoo; Yu, Eunsoo; Park, Cheol-Min] UNIST Ulsan Natl Inst Sci & Technol, Dept Chem, Ulsan 44919, South Korea; [Shin, Seunghoon] Hanyang Univ, Dept Chem, Seoul 04763, South Korea published Metal-Free Synthesis of Indolopyrans and 2,3-Dihydrofurans Based on Tandem Oxidative Cycloaddition in 2020.0, Cited 73.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The synthesis of versatile scaffold indolopyrans based on C-C radical-radical cross-coupling under metal-free conditions is described. The reaction involving single electron transfer between coupling partners followed by cage collapse allows highly selective cross-coupling while employing only equimolar amounts of coupling partners. Moreover, the mechanistic manifold was expanded for the functionalization of enamines to give the stereoselective synthesis of 2,3-dihydrofurans. This iodine-mediated oxidative coupling features mild conditions and fast reaction kinetics.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Choi, S; Oh, H; Sim, J; Yu, E; Shin, S; Park, CM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 100-19-6. I found the field of Chemistry very interesting. Saw the article Synthetic Approaches to Metallo-Supramolecular Co-II Polygons and Potential Use for H2O Oxidation published in 2020.0, Reprint Addresses Schmitt, W (corresponding author), Univ Dublin, Trinity Coll, Sch Chem, Dublin D02 PN40, Ireland.; Schmitt, W (corresponding author), Univ Dublin, Trinity Coll, AMBER Ctr, Dublin D02 PN40, Ireland.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Metal-directed self-assembly has been applied to prepare supramolecular coordination polygons which adopt tetrahedral (1) or trigonal disklike topologies (2). In the solid state, 2 assembles into a stable halide-metal-organic material (Hal-MOM-2), which catalyzes H2O oxidation under photo- and electrocatalytic conditions, operating with a maximum TON = 78 and TOF = 1.26 s(-1). DFT calculations attribute the activity to a Co-III-oxyl species. This study provides the first account of how Co-II imine based supramolecules can be employed as H2O oxidation catalysts.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ako, AM; Kathalikkattil, AC; Elliott, R; Soriano-Lopez, J; McKeogh, IM; Zubair, M; Zhu, NY; Garcia-Melchor, M; Kruger, PE; Schmitt, W or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. In 2019.0 BIOORG CHEM published article about ANTIDIABETIC ACTIVITY; DERIVATIVES; AGENTS; DISCOVERY; EFFICIENT; DOCKING; ACID in [Pogaku, Vinay; Basavoju, Srinivas] Natl Inst Technol, Dept Chem, Warangal 506004, Telangana, India; [Gangarapu, Kiran] Anurag Grp Inst, Sch Pharm, Dept Pharmaceut Chem, Hyderabad 500088, Telangana, India; [Tatapudi, Kiran Kumar; Katragadda, Suresh Babu] CSIR Indian Inst Chem Technol, Ctr Nat Prod & Tradit Knowledge, Hyderabad 500007, Telangana, India in 2019.0, Cited 38.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The aim of the present study is to design and synthesis of new pyrazole-triazolopyrimidine hybrids as potent alpha-glucosidase inhibitors. The target compounds 4a-n were synthesized by one-pot multicomponent approach with good yields and were characterized by various spectroscopic techniques and finally by single crystal X-ray diffraction method (4j). All the newly-synthesized derivatives have been screened for their alpha-glucosidase enzyme inhibition activity and acarbose taken as a standard drug. Among all the tested compounds, 4h has displayed excellent alpha-glucosidase enzyme inhibition activity with IC50 value 12.45 mu M to the standard drug acarbose (IC50: 12.68 mu M). Similarly, the compounds 4f and 4l have exhibited potent activity with IC50 values 14.47 mu M and 17.27 mu M respectively. Structure-activity relationship (SAR) studies of all the title compounds were established. The mode of binding interactions between the alpha-glucosidase enzyme and the compounds were studied. The drug-likeness properties (Lipinski parameters and in silico ADME properties) have predicted for the target compounds. The alpha-glucosidase inhibition, molecular docking and drug-likeness properties of the compounds 4h, 4f and 4l were suggested that these are promising hits for anti-diabetic activity.

Computed Properties of C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Pogaku, V; Gangarapu, K; Basavoju, S; Tatapudi, KK; Katragadda, SB or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Formula: C8H7NO3. Authors Mar’yasov, MA; Kayukov, YS; Nasakin, OE in SPRINGER published article about in [Mar’yasov, M. A.; Kayukov, Ya S.; Nasakin, O. E.] IN Ulyanov Chuvash State Univ, Cheboksary 428010, Russia in 2020.0, Cited 12.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The influence of previously synthesized 2-aroyl-1,1,3,3-tetracyanoprop-2-en-1-ides on the growth of conditionally normal and tumor cells was studied in continuation of a search for new anticancer drugs. Cytotoxicities of the compounds were studied with respect to human tumor cell lines from the ATCC. All compounds were ineffective against melanoma and lung and ovary cancer cell lines and exhibited moderate activity in the other cases. The tested compounds exhibited highly selective effects because they were safe for conditionally normal skin fibroblasts.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Mar’yasov, MA; Kayukov, YS; Nasakin, OE or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article On Water Catalytic Aldol Reaction between Isatins and Acetophenones: Interfacial Hydrogen Bonding and Enamine Mechanism WOS:000473116200008 published article about HENRY NITROALDOL REACTIONS; ORGANIC-SYNTHESIS; ENANTIOSELECTIVE CONSTRUCTION; CONDENSATION; DERIVATIVES; ALDEHYDES in [Han, Jinsong; Zhang, Jin-Lei; Zhang, Wei-Qiang; Gao, Ziwei; Xu, Li-Wen; Jian, Yajun] Shaanxi Normal Univ, Sch Chem & Chem Engn, MOE, Key Lab Appl Surface & Colloid Chem, Xian 710062, Shaanxi, Peoples R China; [Xu, Li-Wen] Hangzhou Normal Univ, Minist Educ, Key Lab Organosilicon Chem & Mat Technol, Hangzhou 310012, Zhejiang, Peoples R China in 2019.0, Cited 38.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

On water catalytic aldol reaction catalyzed by polyetheramine (D230) has been developed for easy access to 3-substituted 3-hydroxyindolin-2-ones through the reaction between various substituted isatins and acetophenones/cyclic ketones in high yields under room temperature. Systematic mechanism investigation uncovers the secret for the on water catalytic aldol reaction: comparison of the heterogeneous and homogeneous reaction circumstances with yields of 95 and 20%, respectively, indicates the on-water reaction dominating; interfacial hydrogen bonding between isatin with H2O is tested based on the downfield shift of the C2 and C3’s C-13 NMR signals when water was added to the CDCl3 solution of isatin; Lewis base polyetheramine D230 catalyzes the aldol reaction via the enamine mechanism verified by in situ NMR and ESI-MS analysis.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Han, JS; Zhang, JL; Zhang, WQ; Gao, ZW; Xu, LW; Jian, YJ or concate me.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Novel nitro based chalcone derivative single crystals: characterization on structural, linear optical, thermal, and third-order nonlinear optical properties WOS:000582463400003 published article about INTERMOLECULAR INTERACTIONS; LIMITING MECHANISMS; GROWTH; ABSORPTION; PHOSPHATE; BEHAVIOR; NLO in [Prabhu, Shobha R.] NMAM Inst Technol, Dept Phys, Karkala 574110, Karnataka, India; [Parol, Vinay; Upadhyaya, V.] Manipal Acad Higher Educ, Manipal Inst Technol, Dept Phys, Manipal 576104, India; [Jayarama, A.] Alvas Inst Engn & Technol, Dept Phys, Moodbidri 574225, India; [Jayarama, A.] Alvas Coll, Dept PG Phys, Moodbidri 574227, India; [Maidur, Shivaraj R.; Patil, Parutagouda Shankaragouda] KLE Inst Technol, Dept Engn Phys, Hubballi 580027, Karnataka, India in 2020.0, Cited 56.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Crystals of (2E)-1-(4-nitrophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (NPTMP) are grown by slow solvent evaporation technique. The compound purity and presence of functional group elements in the material were identified from the spectroscopic techniques (FT-IR and ?H-NMR). The single-phase formation in the bulk powder crystalline sample has been confirmed from powder XRD analysis. The intermolecular interaction and structure-related parameters were obtained and analyzed by utilizing single-crystal XRD data. Using single-crystal XRD data (CIF file), display of the intermolecular interactions and contribution of H center dot center dot center dot H and H center dot center dot center dot O/O center dot center dot center dot H interaction have been obtained. The molecule is mapped over dnorm, de, di, curvedness, shape index, and electrostatic potential by generating the Hirshfeld’s surface of NPTMP molecule. The linear optical absorbance and optical bandgap of the material have been confirmed by UV-VIS-NIR spectroscopic technique. The thermal stability of the crystal NPTMP is obtained from TGA/DTA/DSC techniques. The surface morphology of the crystal is collected from scanning electron microscopy (SEM) and the electronic contribution of hyperpolarizability parameters is obtained from MOPAC 2016 software. The third-order nonlinear optical properties were studied by the Z-scan technique using CW DPSS laser operating at 532 nm wavelength. The molecule exhibits a comparatively moderate optical limiting response due to reverse saturable absorption (RSA).

Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Prabhu, SR; Parol, V; Upadhyaya, V; Jayarama, A; Maidur, SR; Patil, PS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Preparation of chiral alcohols by enantioselective reduction of prochiral ketones with Sinapis alba seeds as biocatalyst WOS:000496611800080 published article about PLANT FRAGMENTS; BIOREDUCTION; CARBONYL; LIPASE; NANOPARTICLES; BIOSYNTHESIS; BIODIESEL; ALDEHYDES; REACTOR; ESTERS in [Almeida de Sousa, Emerson Yvay; Gomes de Lemos, Telma Leda; Queiroz Monte, Francisco Jose] Univ Fed Ceara, Sci Ctr, Program Postgrad Chem, Pici Campus, BR-60455760 Fortaleza, Ceara, Brazil; [Maia da Silva, Francisco Felipe] Fed Inst Educ Sci & Technol Rio Grande Norte, Campus Apodi, BR-59700000 Bento Goncalves, RN, Brazil; [Oliveira de Souza, Juliana Maria] Fed Inst Educ Sci & Technol Ceara, Campus Acarau, BR-62580000 Limoeiro Do Norte, CE, Brazil; [Ferreira, Daniele Alves] Univ Int Integrat Lusofonia Afro Brasileira UNILA, Campus Auroras, BR-62790970 Redencao, CE, Brazil in 2019.0, Cited 44.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The objective of this work is to apply yellow mustard seeds in the enzymatic reduction (biocatalysis) of acetophenone and its derivatives, providing a new biocatalyst for this type of reduction. The reaction parameters were optimized from acetophenone, resulting in 1-phenylethanol, with 68.5% conversion yield and 53% enantiomeric excess (e.e.), analyzed by GC and HPLC, respectively. Reactions to acetophenone and its derivatives were conducted in aqueous medium using buffers pH 6.0 and pH 6.5 in the presence of PVP. A polymer that can act as a protector preventing oxidation of peroxidase enzymes. The results for the derivatives presented low yields (4-18%: substances 5, 7 and 8), moderate (28-40%: substances 3, 4 and 6) and optimum (81%: substance 2) yields, with enantiomeric excesses varying from good to excellent results. Meta-substituted derivatives showed inversion of configuration in the presence of PVP. The biocatalyst was also tested in reactions with other carbonyl compounds, presenting moderate results. In this way, this work offers a new perspective of the application of PVP in biocatalysis reactions and a new biocatalyst for future applications.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact de Sousa, EYA; da Silva, FFM; de Souza, JMO; Ferreira, DA; de Lemos, TLG; Monte, FJQ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem