Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 214894-89-0, Name is 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, molecular formula is C9H9BrO2, 214894-89-0, In a Article, authors is O’Brien, Connor J.£¬once mentioned of 214894-89-0
Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism
The direct cyanomethylation of indoles at the 2- or 3-position was achieved via photoredox catalysis. The versatile nitrile synthon is introduced as a radical generated from bromoacetonitrile, a photocatalyst, and blue LED as a light source. The mechanism of the reaction is explored by determination of the Stern-Volmer quenching constants. By combining photophysical data and mass spectrometry to follow the catalyst decomposition, the catalyst ligands were tuned to enable synthetically useful yields of radical coupling products. A range of indole substrates with alkyl, aryl, halogen, ester, and ether functional groups participate in the reaction, affording products in 16-90% yields. The reaction allows the rapid construction of synthetically useful cyanomethylindoles, products that otherwise require several synthetic steps.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.214894-89-0. In my other articles, you can also check out more blogs about 214894-89-0
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem