With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.31127-39-6,2,3-Dihydrobenzo[b][1,4]dioxine-6-carbaldehyde oxime,as a common compound, the synthetic route is as follows.,31127-39-6
General procedure: A solution of a respective oxime 2a,b or 5a,b (18 mmol) in acetic anhydride (10 mL) was heated to reflux for 8-12 h. Afterwards, the solvent was then removed in vacuo, the residue was quenched by adding cold water (10 mL), and keeping the temperature of the resulting mixture at 15-20C for 1-2 h. The formed precipitate was isolated, and dried at 40oC to give title compounds 3a,b or 6a,b, respectively.
The synthetic route of 31127-39-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Le-Nhat-Thuy, Giang; Dinh, Thuy Van; Pham-The, Hai; Nguyen Quang, Hung; Nguyen Thi, Nga; Dang Thi, Tuyet Anh; Hoang Thi, Phuong; Le Thi, Tu Anh; Nguyen, Ha Thanh; Nguyen Thanh, Phuong; Le Duc, Trung; Nguyen, Tuyen Van; Bioorganic and Medicinal Chemistry Letters; vol. 28; 23-24; (2018); p. 3741 – 3747;,
Benzodioxan
1,4-Benzodioxane | C8H8O2 – PubChem