Chen, CH; Hou, CQ; Chen, PH; Liu, GS in [Chen, Chaohuang; Hou, Chuanqi; Chen, Pinhong; Liu, Guosheng] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Ctr Excellence Mol Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Liu, Guosheng] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hongkong Joint Lab Chem Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China published Palladium(II)-Catalyzed Aminotrifluoromethoxylation of Alkenes: Mechanistic Insight into the Effect of N-Protecting Groups in 2020, Cited 59. Application In Synthesis of 2,2-Diphenylacetonitrile. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.
The Summary of main observation and conclusion An efficient palladium-catalyzed regioselective 5-exo aminotrifluoromethoxylation of alkenes has been established herein, which provides a practical route towards the synthesis of OCF3-containing pyrrolidines. tert-Butyloxycarbonyl (Boc) as an amino protecting group plays a significant role in both the chemo- and regioselectivities. In addition, preliminary mechanistic studies reveal that the amino protecting group of substrates and the counter anion of palladium catalyst play critical roles in reaction efficiency presumably due to an isomerization of alkyl- Pd(II) intermediates. Moreover, the asymmetric 5-exo aminotrifluoromethoxylation reaction has also been achieved by introducing a sterically bulky pyridinyl-oxazoline ligand.
About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Chen, CH; Hou, CQ; Chen, PH; Liu, GS or concate me.. Application In Synthesis of 2,2-Diphenylacetonitrile
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem