Safety of 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Organocatalytic asymmetric vinylogous 1,4-addition of alpha,alpha-Dicyanoolefins to chalcones under a bio-based reaction media: Discovery of new Michael adducts with antiplasmodial activity published in 2019.0, Reprint Addresses Correa, AG (corresponding author), Univ Fed Sao Carlos, Ctr Excellence Res Sustainable Chem, Dept Chem, BR-13565905 Sao Carlos, SP, Brazil.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.
The organocatalysed asymmetric vinylogous Michael addition of alpha,alpha-dicyanoolefins to alpha,beta-unsaturated aldehydes and ketones have been reported in the last decade, however, chalcones have been poorly explored. Moreover, a considerable part of the publications in this theme still employs undesirable solvents, such as toluene and THF, with concerns related to health and environmental safety. We report herein the use of a bifunctional catalyst derived from a Cinchona alkaloid to perform the enantio- and diastereoselective Michael addition of alpha,alpha-dicyanoolefins to chalcones using 2-MeTHF as solvent. The Michael adducts were obtained in moderate to good yields and were evaluated for their antiplasmodial and cytotoxic activity. (C) 2019 Elsevier Ltd. All rights reserved.
Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Martelli, LSR; Vieira, LCC; Paixao, MW; Zukerman-Schpector, J; de Souza, JO; Aguiar, ACC; Oliva, G; Guido, RVC; Correa, AG or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem