One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C8H8O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 10288-72-9, Name is 6-Hydroxy-1,4-benzodioxane, molecular formula is C8H8O3
Near-Infrared Photoswitching of Azobenzenes under Physiological Conditions
Biological tissue exhibits an absorbance minimum in the near-infrared between 700 and 900 nm that permits deep penetration of light. Molecules that undergo photoisomerization in this bio-optical window are highly desirable as core structures for the development of photopharmaceuticals and as components of chemical-biological tools. We report the systematic design, synthesis, and testing of an azobenzene derivative tailored to undergo single-photon photoswitching with near-infrared light under physiological conditions. A fused dioxane ring and a methoxy substituent were used to place oxygen atoms in all four ortho positions, as well as two meta positions, relative to the azobenzene N=N double bond. This substitution pattern, together with a para pyrrolidine group, raises the pKa of the molecule so that it is protonated at physiological pH and absorbs at wavelengths >700 nm. This azobenzene derivative, termed DOM-azo, is stable for months in neutral aqueous solutions, undergoes trans-to-cis photoswitching with 720 nm light, and thermally reverts to the stable trans isomer with a half-life near 1 s.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. HPLC of Formula: C8H8O3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10288-72-9, in my other articles.
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem