Related Products of 214894-89-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.214894-89-0, Name is 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, molecular formula is C9H9BrO2. In a article£¬once mentioned of 214894-89-0
2-Aralkoxyadenosines: Potent and Selective Agonists at the Coronary Artery A2 Adenosine Receptor
A Langendorff guines pig heart preparation served for the assay of agonist potency of a series of 26 2-aralkoxyadenosines at the A1 and A2 receptors of, respectively, the atrioventricular node (conduction block) and coronary arteries (vasodilation).All of the analogues are weak agonists at the A1 receptor, requiring concentrations >9 muM to cause second degree heart block.At the A2 receptor 2-phenethoxyadenosine is the most potent of the 2-phenylalkyladenosines.The activity of ring-substituted (F, Cl, CH3, and OCH3) 2-phenethoxyadenosines increases ortho < meta < para.The EC50s of coronary vasoactivity of several para-substituted analogues are in the subnanomolar range.The most potent analogue, 2-<2-(4-methylphenyl)ethoxy>adenosine 19, has an EC50 for coronary vasodilation of 190 pM and an A1/A2 selectivity ratio of 44000.Aryl groups such as thienyl, indoloyl, or naphthyl also support A2 agonist activity.Although 2-oxoadenosine is 3 times more vasoactive than 2-aminoadenosine, the activites of the phenyl derivatives are markedly different; 2-phenoxyadenosine is 23 times weaker than 2-(phenylamino)adenosine (CV-1808).
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 214894-89-0
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem