In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called An Organometallic Isostere of an Amino Acid, published in 2021-07-19, which mentions a compound: 1762-34-1, mainly applied to rhenium carbonyl bipyridine complex amino acid isostere preparation resolution; crystal structure rhenium carbonyl bipyridine complex amino acid isostere; mol structure rhenium carbonyl bipyridine complex amino acid isostere, Category: benzodioxans.
Rhenium carbonyl complexes with substituted 2,2′-bipyridines I (2a-4a, X = Cl, R1, R2: H, H; EtOCO, Et; Fmoc, H; 2b-4b, X = Br, R1, R2: H, H; EtOCO, Et; Fmoc, H) were prepared as amino acid isosteres and resolved by chiral chromatog. An organometallic complex that mimics an amino acid, also known as an amino acid isostere, can be synthesized from a functionalized bipyridine ligand and a fac-[Re(CO)3]+ center. The reaction of an achiral ligand and metal results in a racemic mixture of chiral-at-metal complexes. These metal species have amine and carboxy termini, a side chain type unit that can be varied, as well as the chiral metal that is analogous to the α carbon of an amino acid. The racemic mixtures can be separated into enantiomers by chiral chromatog., and the metal complexes can be incorporated into peptides by using solid-phase peptide synthesis.
Compounds in my other articles are similar to this one(5,5′-Dimethyl-2,2′-bipyridine)Category: benzodioxans, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.