Wang, Rui; Ranganathan, Srivathsan V.; Haruehanroengra, Phensinee; Mao, Song; Scalabrin, Matteo; Fabris, Daniele; Chen, Alan; Liu, Hehua; Hassan, Abdalla E. A.; Gan, Jianhua; Sheng, Jia published an article about the compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1,SMILESS:CC1=CN=C(C=C1)C1=NC=C(C)C=C1 ).Category: benzodioxans. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1762-34-1) through the article.
The facile construction of metal-DNA complexes using ‘Click’ reactions is reported here. A series of 2′-propargyl-modified DNA oligonucleotides were initially synthesized as structure scaffolds and were then modified through ‘Click’ reaction to incorporate a bipyridine ligand equipped with an azido group. These metal chelating ligands can be placed in the DNA context in site-specific fashion to provide versatile templates for binding various metal ions, which are exchangeable using a simple EDTA washing-and-filtration step. The constructed metal-DNA complexes were found to be thermally stable. Their structures were explored by solving a crystal structure of a propargyl-modified DNA duplex and installing the bipyridine ligands by mol. modeling and simulation. These metal-DNA complexes could have wide applications as novel organometallic catalysts, artificial RNases, and potential metal delivery systems.
This literature about this compound(1762-34-1)Category: benzodioxanshas given us a lot of inspiration, and I hope that the research on this compound(5,5′-Dimethyl-2,2′-bipyridine) can be further advanced. Maybe we can get more compounds in a similar way.