Formula: C8H7NO3. In 2020.0 BIOORG CHEM published article about FRUGIPERDA LEPIDOPTERA-NOCTUIDAE; INSECTICIDAL ACTIVITY; EFFLUX PUMP; SEMISYNTHESIS; DERIVATIVES; INHIBITION; PESTICIDES; MOSQUITO; AMIDES in [Tantawy, Ahmed H.; Wang, Man-Qun] Huazhong Agr Univ, Coll Plant Sci & Technol, Hubei Insect Resources Utilizat & Sustainable Pes, Wuhan 430070, Hubei, Peoples R China; [Tantawy, Ahmed H.; Jiang, Hong] Huazhong Agr Univ, Coll Sci, Dept Chem, Wuhan 430070, Hubei, Peoples R China; [Tantawy, Ahmed H.] Benha Univ, Coll Sci, Dept Chem, Banha 13518, Egypt; [Farag, Shaimaa M.] Ain Shams Univ, Dept Entomol, Fac Sci, El Abaseya, Egypt; [Hegazy, Lamees] Washington Univ, Ctr Clin Pharmacol, Sch Med, St Louis, MO 63110 USA; [Hegazy, Lamees] St Louis Coll Pharm, St Louis, MO 63110 USA in 2020.0, Cited 45.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.
A series of piperine-based dienehydrazide derivatives were designed and synthesized to be used as insecticides against Culex pipiens. The chemical structure of compound 5n was confirmed by single-crystal x-ray diffraction. Their insecticidal activities of synthesized compounds were tested against third-instar larval of Cx. pipiens at concentrations ranging from 0.1 to 1.2 mg/mL. Among all derivatives, compounds 5a, 5b, 5f, 5g, 5m, 5n, 5o, 5p, and 5u displayed good activities. The final mortality rates at the concentration of 0.75 mg/mL after 48 h treatment, were found to be in the range from 80.00 to 83.33% and with LC50 values ranging from 0.221 to 0.094 mg/mL. These compounds demonstrated higher insecticidal activities than piperine and Deltamethrin (a commercial positive control). Molecular modelling reveals several molecular interactions between synthesized compounds and the substrate binding sits of acetylcholinesterase (AChE) that are predicted to be responsible for its binding and inhibition activity.
Welcome to talk about 100-19-6, If you have any questions, you can contact Tantawy, AH; Farag, SM; Hegazy, L; Jiang, H; Wang, MQ or send Email.. Formula: C8H7NO3
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem