Downstream synthetic route of (2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol

With the synthetic route has been constantly updated, we look forward to future research findings about (2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol,belong benzodioxans compound

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO279,mainly used in chemical industry, its synthesis route is as follows.,274910-19-9

(2, 3-Dihydrobenzor1, 41dioxin-5-yl)-chloromethane; Dissolve (2,3-Dihydrobenzo [1, 4] dioxin-5-yl) methanol (1.8 g, 10.8 mmol) in dichloromethane (15 mL). Add neat thionyl chloride (2 mL, 27.4 mmol) dropwise to the stirring reaction mixture at 25C under nitrogen. Stir the reaction for 15 minutes and concentrate under reduced pressure to obtain 2.0 g (100%) of the desired compound as a yellow oil. HRMS : m/z = 184.0290 (M)

With the synthetic route has been constantly updated, we look forward to future research findings about (2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methanol,belong benzodioxans compound

Reference£º
Patent; ELI LILLY AND COMPANY; WO2003/76442; (2003); A1;,
Benzodioxan
1,4-Benzodioxane | C8H8O2 – PubChem