SDS of cas: 22013-33-8, In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. 22013-33-8, Name is 2,3-Dihydrobenzo[b][1,4]dioxin-6-amine,introducing its new discovery.
The novel N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine compound is designed and subjected to structural studies, inhibition of sPLA2, and molecular docking. The compound was synthesized by condensation of 1,4-benzodioxan-6-amine and 4-bromobenzaldehyde and characterized by various spectral techniques. Single crystal X-ray diffraction analysis confirmed the 3D molecular structure and established the different intermolecular interactions responsible for the crystal structure stability. Further synthesized compound was evaluated for anti-inflammatory activity using sPLA2 inhibition by indirect hemolytic assay. The compound showed good inhibition against sPLA2 enzyme compared with standard diclofenac, which is validated by molecular docking with a ?7.60 kcal/mol docking score.
I am very proud of our efforts over the past few months and hope to 22013-33-8 help many people in the next few years. SDS of cas: 22013-33-8