Application of 10288-72-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.10288-72-9, Name is 6-Hydroxy-1,4-benzodioxane, molecular formula is C8H8O3. In a article£¬once mentioned of 10288-72-9
A Direct Synthesis of 2-(omega-Carboxyalkyl)isoflavones from ortho-Hydroxylated Deoxybenzoins
As part of a program focused on the development of new antineoplastic agents based on scaffolds found in natural products, we explored the isoflavone family as potential enzyme inhibitors. We required biotin-modified isoflavones to identify potential biological targets, and we selected the C-2 position in isoflavones as an attachment site for an alkyl group bearing a terminal carboxylic acid to which we could attach a biotin derivative. The base-catalyzed condensation of 2,4-dihydroxy-substituted deoxybenzoins with cyclic anhydrides mediated by a combination of triethylamine and 1,8-diazabicyclo[5.4.0]undec-7-ene led to an efficient synthesis of the desired 2-(omega-carboxyalkyl)isoflavones with functional groups at C-5, 6 and 7 and with various substituents in the C-3 phenyl group.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 10288-72-9
Reference£º
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem