Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. In a patent，Which mentioned a new discovery about Related Products of 2879-20-1, Related Products of 2879-20-1
Herein is described the synthesis and structure-activity relationship of a novel series of aromatic and heteroaromatic 3-(1-benzyl-4-piperidinyl)propan-1-one derivatives that display potent and selective inhibition of the enzyme acetylcholinesterase (AChE). 1-(2-Methyl-6-benzothiazolyl)-3-(N-benzyl-4-piperidinyl)propan-1-one hydrochloride, 6d, is one of the most active compounds within this series exhibiting an IC50 for the inhibition of the AChE enzyme equal to 6.8 nM.Compound 6d has shown a dose-dependent elevation of total acetylcholine (ACh) levels in the mouse forebrain with an oral ED50 = 9.8 mg/kg.In addition, in vivo microdialysis experiments in the rat demonstrate that 6d increases extracellular ACh (100percent over basal) 1-3 h postdose with an oral ED50 = 4.8 mg/kg.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Related Products of 2879-20-1, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 2879-20-1