Month: April 2022

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1762-34-1, is researched, SMILESS is CC1=CN=C(C=C1)C1=NC=C(C)C=C1, Molecular C12H12N2Journal, Journal of Materials Chemistry C: Materials for Optical and Electronic Devices called Molecular engineering towards tunable morphology of metal-organic complex microcrystals for efficient and multicolor electrochemiluminescence, Author is Ding, Chun-Yun; Shao, Jiang-Yang; Gong, Zhong-Liang; Zhong, Yu-Wu; Yao, Jiannian, the main research direction is mol engineering towards tunable morphol metal organic complex microcrystals; multicolor electrochemiluminescence.Computed Properties of C12H12N2.

Electrochemiluminescence (ECL) of crystalline materials has recently attracted increasing attention due to their unique characteristics and applications, such as crystallization-induced emission, active waveguiding, and biosensing. Tris(2,2′-bipyridine)ruthenium(II), [Ru(bpy)3]2+, a classical metal-organic complex for ECL studies, has been fully investigated in solution as well as its derivatives However, the dependence of ECL properties on the mol. structure and crystal morphol. of these complexes has not been illustrated, partially due to the difficulty in the controlled crystal growth. Here, we adopt a facile mol. engineering strategy to obtain microcrystals of [Ru(bpy)3]2+ derivatives with well-defined morphol. (rods, wires, or polyhedrons) and varied phosphorescence emission colors (yellow, orange, and red) by simply changing the position and number of Me substituents on the bipyridine ligands. The packing modes of mols. influenced by Me groups play a vital role in crystal growth based on attachment energy anal. The obtained microcrystals could act as ECL luminophores when modified on glassy carbon electrode surfaces. Those with one-dimensional (1D) morphol. generally show superior ECL efficiency and stability to three-dimensional (3D) shaped microcrystals. ECL biosensors made of stable 1D microcrystals show reliable and sensitive responses to hydroxyproline, demonstrating their capacity in recyclable detections. This work demonstrates the great potential of mol. engineering in controlling the morphol., emission colors, and ECL properties of mol. crystals, paving the way for the development of high-performance ECL biosensing and optoelectronic devices.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Computed Properties of C12H12N2, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1762-34-1, is researched, Molecular C12H12N2, about Ru(II)/N-N/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (N-N = diimine or diamine), the main research direction is ruthenium dipyridylamine diimine complex preparation crystal structure; electrochem antitumor activity lipophilicity ruthenium dipyridylamine diimine complex; DNA HSA binding ruthenium dipyridylamine diimine complex.Quality Control of 5,5′-Dimethyl-2,2′-bipyridine.

The rational design of anticancer agents that acts in specific biol. targets is one of the most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new ruthenium(II) compounds with good cytotoxicity against tumor cells, a series of new complexes of general formula [RuCl(PPh3)(Hdpa)(N-N)]Cl [PPh3 = triphenylphosphine, N-N = 2,2′-dipyridylamine (Hdpa) (1), 1,2-diaminoethane (en) (2), 2,2′-bipyridine (bipy) (3), 5,5′-dimethyl-2,2′-bipyridine (dmbipy) (4), 1,10-phenanthroline (phen) (5) and 4,7-diphenyl-1,10-phenanthroline (dphphen) (6)] were synthesized. The complexes were characterized by elemental anal. and spectroscopic techniques (IR, UV/Visible, and 1D and 2D NMR) and three of their x-ray structures were determined: [RuCl(PPh3)(Hdpa)2]Cl, [RuCl(PPh3)(Hdpa)(en)]Cl and [RuCl(PPh3)(Hdpa)(dmbipy)]Cl. All the complexes are more cytotoxic against the cancer cell line than against the non-tumor cell line, highlighting complexes 1 and 5, which have an index selectivity of 18 and 15, resp. The binding constants of compounds 1-6 with human serum albumin (HSA) were determined by tryptophan fluorescence quenching, indicating moderate to strong interactions. The binding mode of the complexes to calf thymus (CT) DNA was explored by several techniques, which reveal that only the dphphen compound 6 causes distortions in the secondary and tertiary structures of DNA. The nature of the N-N co-ligand and the presence of the PPh3 and Hdpa ligands are features that can influence the binding affinity of the complexes by the biomols. and in the cytotoxic activity of the complexes. Overall, the complexes with diimine co-ligand are much more cytotoxic than compound 2 with the aliphatic diamine.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Quality Control of 5,5′-Dimethyl-2,2′-bipyridine, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Group 6 Metal Complexes as Electrocatalysts of CO2 Reduction: Strong Substituent Control of the Reduction Path of [Mo(η3-allyl)(CO)2(x,x’-dimethyl-2,2′-bipyridine)(NCS)] (x = 4-6), the main research direction is methylbipyridine allyl molybdenum carbonyl complex preparation redox potential DFT; crystal structure methylbipyridine allyl molybdenum carbonyl complex; mol structure methylbipyridine allyl molybdenum carbonyl complex; optimized geometry bipyridine allylmolybdenum complex anion radical complex DFT.Related Products of 1762-34-1.

[Mo(η3-allyl)(CO)2(x,x’-dmbipy)(NCS)] (dmbipy = dimethyl-2,2′-bipyridine; x = 4-6) were synthesized and their electrochem. reduction studied using combined cyclic voltammetry (CV) and variable-temperature spectroelectrochem. (IR/UV-visible SEC) in THF and butyronitrile (PrCN), at Au and Pt electrodes. The exptl. results, strongly supported by d. functional theory (DFT) calculations, indicate that the general cathodic path of these Group 6 organometallic complexes is closely related to that of the intensively studied class of Mn tricarbonyl α-diimine complexes, which, themselves, have recently been identified as important smart materials for catalytic CO2 reduction The di-Me substitution on the 2,2′-bipyridine ligand backbone has presented new insights into this emerging class of catalysts. For the 1st time, the 2e- reduced 5-coordinate anions [Mo(η3-allyl)(CO)2(x,x’-dmbipy)]- were directly observed with IR spectroelectrochem. (IR SEC). The role of steric and electronic effects in determining the reduction-induced reactivity was also studied. For the 6,6′-dmbipy, the primary 1e- reduced radical anions exert unusual stability, radically changing the follow-up cathodic path. The 5-coordinate anion [Mo(η3-allyl)(CO)2(6,6′-dmbipy)]- remains stable at low temperature in strongly coordinating butyronitrile and does not undergo dimerization at elevated temperature, in sharp contrast to reactive [Mo(η3-allyl)(CO)2(4,4′-dmbipy)]- that tends to dimerize in a reaction with the parent complex. The complex with the 5,5′-dmbipy ligand combines both types of reactivity. Under aprotic conditions, the different properties of [Mo(η3-allyl)(CO)2(x,x’-dmbipy)]- are also reflected in their reactivity toward CO2. Preliminary CV and IR SEC results reveal differences in the strength of CO2 coordination at the free axial position. Catalytic waves attributed to the generation of the 5-coordinate anions were observed using CV, but only a modest catalytic performance toward the production of formate was demonstrated by IR SEC. For 6,6′-dmbipy, a stronger catalytic effect was observed for the Au cathode, compared to Pt.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Related Products of 1762-34-1, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Application In Synthesis of 5,5′-Dimethyl-2,2′-bipyridine. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Two novel Sm(III) complexes with different aromatic carboxylic acid ligands: Synthesis, crystal structures, luminescence and thermal properties. Author is Zhu, Min-Min; Cui, Jing; Zeng, Yan-Li; Ren, Ning; Zhang, Jian-Jun.

Two novel Sm(III) complexes, [Sm(3,4-DMBA)3(3,4-DMHBA)(5,5′-DM-2,2′-bipy)]2 (1), [Sm(3-MOBA)3(5,5′-DM-2,2′-bipy)]2 (2) (3,4-dimethylbenzoic acid = 3,4-DMHBA, 3-methoxybenzoic acid = 3-MOHBA and 5,5′-dimethyl-2,2′-bipyridine = 5,5′-DM-2,2′-bipy), were successfully synthesized and assembled. The crystal structures were determined by single crystal x-ray diffraction. Two complexes were characterized by the elemental anal., IR, powder x-ray diffraction, thermal gravimetric technol. Because of the different ligands, the structures of the two complexes are very different, especially the structure of the complex 1. Each central Sm(III) ion of complex 1 was coordinated by three deprotonated 3,4-DMBA-,one unprotonated 3,4-DMHBA and one 5,5′-DM-2,2′-bipy, which has rarely been reported before. However each central Sm(III) ion of complex 2 was only coordinated via three deprotonated 3-MOBA- and one 5,5′-DM-2,2′-bipy. In addition, the thermal decomposition mechanism and the three-dimensional IR accumulation spectra of the evolved gas during the thermal decomposition for two complexes were studied by the simultaneous TG/DSC-FTIR technol. What’s more, the luminescence properties of two complexes are also discussed. Finally, the bacteriostatic activities of two complexes were evaluated against Staphlococcus aureus, Escherichia coli and Candida albicans.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Application In Synthesis of 5,5′-Dimethyl-2,2′-bipyridine, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C12H12N2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Catalytic hydrogenation of aldehydes and ketones using cinchona-bipyridyl-based palladium catalyst. Author is Chidambaram, Ramasamy R.; Sadhasivam, Velu; Mariyappan, Mathappan; Siva, Ayyanar.

Understanding the need for simple, robust and low effluents, in chem. processes, an elegant protocol was developed for the catalytic reduction of aldehydes and ketones to corresponding alcs. which were used in synthetic fragrance applications using cinchona alkaloid-derived palladium catalyst. This system holds good for very low catalyst loading surfaces with the formation of fewer impurities and negligible decomposition under moderate pressure. The conversions and yields ranges from moderate to good (60-80%).

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)COA of Formula: C12H12N2, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Gomez-Gonzalez, Jacobo; Bouzada, David; Perez-Marquez, Lidia A.; Sciortino, Giuseppe; Marechal, Jean-Didier; Vazquez Lopez, Miguel; Vazquez, M. Eugenio published the article 《Stereoselective self-assembly of DNA binding helicates directed by the viral β-annulus trimeric peptide motif》. Keywords: peptide solid phase synthesis bipyridine self assembly chiral helicate; chiral peptide helicate complexation iron DNA binding; bipyridine peptide supramol structure MD simulation fluorescence; iron complex peptide stability.They researched the compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1 ).HPLC of Formula: 1762-34-1. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1762-34-1) here.

Combining coordination chem. and peptide engineering offers extraordinary opportunities for developing novel mol. (supra)structures. Here, we demonstrate that the β-annulus motif is capable of directing the stereoselective assembly of designed peptides containing 2,2′-bipyridine ligands into parallel three-stranded chiral peptide helicates, and that these helicates selectively bind with high affinity to three-way DNA junctions.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)HPLC of Formula: 1762-34-1, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 5,5′-Dimethyl-2,2′-bipyridine. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Synthesis, structural characterization and in vitro cytotoxic evaluation of mixed Cu(II)/Co(II) levofloxacin-bipyridyl complexes. Author is Bashir, Masrat; Yousuf, Imtiyaz.

This work features synthesis, structural characterization and biol. evaluation of two Cu(II)/Co(II)-based complexes (1 and 2) synthesized from levofloxacin (lvXn) and bipyridyl ligands. The structural elucidation of complexes 1 and 2 was carried out by anal., spectral (UV-vis, FTIR, EPR) and single crystal x-ray crystallog. techniques. The crystallog. details of complex 1 revealed a triclinic crystal system with P-1 space group and lattice parameters a = 10.32(7) Å, b = 11.75(8) Å, c = 14.85(9) Å, and α = 87.40°, β = 77.55°, γ = 66.26°. The DFT studies were performed to study the electronic structure and localization of HOMO and LUMO electron densities on the complexes. authors have also performed comparative in vitro DNA/BSA binding studies of complexes 1 and 2 by multispectroscopic methods to evaluate the cytotoxic potential of synthesized complexes which revealed better binding potential of copper analog. Furthermore, the cytotoxic assessment of copper analog was examined on a panel of five human cancer cell lines employing SRB assay which revealed remarkably good and selective cytotoxic activity towards A498 (kidney), HeLa (cervical) and HepG2 (hepatoma) cancer cell lines.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Safety of 5,5′-Dimethyl-2,2′-bipyridine, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 1762-34-1. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Regulating the magnetic dynamics of mononuclear β-diketone Dy(III) single-molecule magnets through the substitution effect on capping N-donor coligands. Author is Xi, Jing; Ma, Xiufang; Cen, Peipei; Wu, Yuewei; Zhang, Yi-Quan; Guo, Yan; Yang, Jinhui; Chen, Lei; Liu, Xiangyu.

A series of five mononuclear β-diketonate-Dy(III) complexes, with formulas Dy(ntfa)3(Br-bpy) (1), Dy(ntfa)3(Br2-bpy) (2), Dy(ntfa)3(5,5-(CH3)2-bpy) (3), Dy(ntfa)3(4,4-((CH3)3)2-bpy) (4) and Dy(ntfa)3(4,4-(CH3)2-bpy) (5) (ntfa = 4,4,4-trifluoro-1-(2-naphthyl)-1,3-butanedione, Br-bpy = 5-bromo-2,2′-bipyridine, Br2-bpy = 4,4′-dibromo-2,2′-bipyridine, 5,5-(CH3)2-bpy = 5,5′-di-methyl-2,2′-bipyridine, 4,4-((CH3)3)2-bpy = 4,4′-di-tert-butyl-2,2′-bipyridine, and 4,4-(CH3)2-bpy = 4,4′-di-methyl-2,2′-bipyridine), have been prepared by altering the capping N-donor coligands. Dy(III) ions in all complexes possess N2O6 octa-coordinated environments, displaying a distorted square antiprismatic D4d symmetry in complexes 1-4, as well as a triangular dodecahedron D2d symmetry in 5. Magnetic investigations evidence the SIM behavior in the five complexes with the energy barriers (Ueff) of 104.19 K (1), 122.93 K (2), 84.20 K (3), 64.16 K (4) and 80.23 K (5) under zero applied dc field. The potential QTM effects in the title complexes are successfully suppressed in the presence of the extra applied fields. The crystal field parameters and orientations of the magnetic easy axes were obtained from the simulation of the magnetic data and the electrostatic model calculation The distinct electronic effects originating from the subtle changes of the substituents on the capping N-donor coligands induce varying coordination microenvironments and geometries on the Dy(III) sites, further drastically impacting the overall magnetic properties of the title complexes. The disparities of the uniaxial anisotropy and the magnetic dynamics for 1-5 have been elucidated by ab initio calculations as well.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)SDS of cas: 1762-34-1, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1 ) is researched.Reference of 5,5′-Dimethyl-2,2′-bipyridine.Santoro, Antonio; Holub, Jan; Fik-Jaskolka, Marta A.; Vantomme, Ghislaine; Lehn, Jean-Marie published the article 《Dynamic Helicates Self-Assembly from Homo- and Heterotopic Dynamic Covalent Ligand Strands》 about this compound( cas:1762-34-1 ) in Chemistry – A European Journal. Keywords: transition metal schiff base helicate complex preparation self assembly; crystal structure transition metal schiff base helicate; double-helical structures; dynamic covalent chemistry; metallo-supramolecular structures; programmed self-assembly. Let’s learn more about this compound (cas:1762-34-1).

The understanding and the application of reversible covalent reactions and coordination chem. together with the proper design of the mol. frameworks, allow to achieve not only well-defined output architectures but also different grades of complex behavior. In this work, the dynamic nature of the helical systems offers an addnl. level of complexity by combining self-sorting on two levels: (1) the build-up of the ligand strand constituents from their components through dynamic covalent chem.; (2) the assembly of the helicates from the ligands and the metal cations through dynamic metallo-supramol. chem. The information encoded in the ligands constituent mol. was read differently (and accurately at the same time) by metal cations that varied in the coordination algorithms. It enabled the selective formation of a specific type of helicates from a wide library of helicates formed by the possible combination of subcomponents. Ligands containing dynamic tridentate and/or bidentate binding motifs in the same strand were studied to explore the helicates self-assembly with appropriate metal cations.

There is still a lot of research devoted to this compound(SMILES：CC1=CN=C(C=C1)C1=NC=C(C)C=C1)Reference of 5,5′-Dimethyl-2,2′-bipyridine, and with the development of science, more effects of this compound(1762-34-1) can be discovered.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Application of 1762-34-1. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about A new mononuclear nickel complex with 5,5′-dimethyl-2,2′-bipyridine: Synthesis, structural investigation and catalytic properties. Author is Jaballi, Rim; Atoui, Dhieb; Maalej, Wassim; Babaryk, Artem; Horcajada, Patricia; Ben Salem, Ridha; Elaoud, Zakaria.

The new [Ni(dmbpy)(H2O)4]SeO4 (1) complex (dmbpy = 5,5′-dimethyl-2,2′-bipyridine or C12H12N2), based on mononuclear nickel(II) and bi-at. bridging ligands was successfully synthesized by hydrothermal method. The crystals were characterized by x-ray single-crystal diffraction, crystallizing in the monoclinic system, space group P21/c. Their crystal structure consists of metallic cations octahedrally coordinated by four water mols. and two nitrogen atoms coming from the organic mol. [NiN2O4], and a selenate anion (SeO4)2-. Their crystal packing is ensured by a three-dimensional network of O-H. O hydrogen bonds between the cation and anion moieties, and π… π interactions between the pyridine rings of the organic moieties of the same layer. The thermal anal. discloses dehydration between 148° and 210°, leading to an anhydrous compound [Ni(dmbpy)]SeO4. The study of vibrational absorption and Raman scattering spectra allows bringing addnl. information to those obtained by x-ray diffraction. The optical band gap was calculated from the UV-visible absorbance spectra using classical Tauc relation which is 3.58 eV. The catalytic evaluation of [Ni(dmbpy)(H2O)4]SeO4 on Heck and Sonogashira coupling reactions, activated by ultrasonic irradiation, results in encouraging yields for a very short times with a remarkable selectivity of the form (E) with respect to (Z) during the arylation of styrene, making this complex a promising catalyst for both types of reactions. The coupling products of the Heck and Sonogashira coupling reaction ((Z)-/(E)- Stilbene and Diphenylacetylene, resp.) were examined by 13C NMR and 1H NMR. These spectroscopic measurements provide extremely valuable information on the structure of the mols. obtained.

If you want to learn more about this compound(5,5′-Dimethyl-2,2′-bipyridine)Application of 1762-34-1, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1762-34-1).

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem