Derivation of elementary reaction about 1762-34-1

Compound(1762-34-1)Related Products of 1762-34-1 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1762-34-1, is researched, SMILESS is CC1=CN=C(C=C1)C1=NC=C(C)C=C1, Molecular C12H12N2Journal, Journal of Coordination Chemistry called Five new cobalt(II) complexes based on indazole derivatives: synthesis, DNA binding and molecular docking study, Author is Long, Bing-Fan; Huang, Qin; Wang, Shu-Long; Mi, Yan; Wang, Meng-Fan; Xiong, Ting; Zhang, Shu-Cong; Yin, Xian-Hong; Hu, Fei-Long, the main research direction is preparation cobalt indazole derivative bipy phen complex; crystal structure cobalt indazole derivative bipy phen complex; DNA interaction cobalt indazole derivative bipy phen complex; thermal decomposition cobalt indazole derivative bipy phen complex.Related Products of 1762-34-1.

Five cobalt(II) complexes based on 1H-indazole-3-carboxylic acid (H2L), [Co(phen)(HL)2]·H2O (1), [Co(5,5′-dimethyl-2,2′-bipy)(HL)2] (2), [Co(2,2′-bipy)2(HL)]·5H2O (3), [Co2(2,9-dimethyl-1,10-phen)2(L)2] (4) and [Co2(6,6′-dimethyl-2,2′-bipy)2(L)2]·H2O (5) (2,2′-bipy = 2,2′-bipyridine, phen = 1,10-phenanthroline), were synthesized and structurally characterized by elemental analyses, IR and UV-visible spectroscopies and single-crystal X-ray crystallog. 1-3 Possess mononuclear Co(II) structures, while 4 and 5 exhibit binuclear structure. 1D water tape which is linked by the multiple hydrogen bonds was embedded in the 3D motif of complex 3. Complexes 4 and 5 show two orthogonal planes of motif that was constituted by phen/2,2′-bipy and indazole acid, resp. The intermol. interactions including hydrogen bonding and π-π stacking interactions are stabilizing these complexes. The interactions of the synthesized complexes with calf-thymus DNA (CT-DNA) were studied by UV-visible absorption titration, ethidium bromide displacement assay and viscosity measurements. The complexes could interact with CT-DNA via a groove binding mode. Their behavior rationalization was further theor. studied by mol. docking.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Brief introduction of 1799971-34-8

Compound(1799971-34-8)Safety of (S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate), if you are interested, you can check out my other related articles.

Safety of (S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate, is researched, Molecular C10H18N2O3, CAS is 1799971-34-8, about Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists. Author is Rudolph, Dale A.; Alcazar, Jesus; Ameriks, Michael K.; Anton, Ana Belen; Ao, Hong; Bonaventure, Pascal; Carruthers, Nicholas I.; Chrovian, Christa C.; De Angelis, Meri; Lord, Brian; Rech, Jason C.; Wang, Qi; Bhattacharya, Anindya; Andres, Jose Ignacio; Letavic, Michael A..

The optimization efforts that led to a novel series of Me substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones that are potent rat and human P2X7 antagonists are described. These efforts resulted in the discovery of compounds with good drug-like properties that are capable of high P2X7 receptor occupancy in rat following oral administration, including compounds I (P2X7 IC50 = 7.7 nM) and II (P2X7 IC50 = 7.7 nM). These compounds are expected to be useful tools for characterizing the effects of P2X7 antagonism in models of depression and epilepsy, and several of the compounds prepared are candidates for effective P2X7 PET tracers.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Top Picks: new discover of 1762-34-1

Compound(1762-34-1)Related Products of 1762-34-1 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1762-34-1, is researched, Molecular C12H12N2, about Nickel-Catalyzed Cross-Electrophile C(sp3)-Si Coupling of Unactivated Alkyl Bromides with Vinyl Chlorosilanes, the main research direction is nickel catalyst cross coupling alkyl bromide vinyl chloro silane; alkyl silane organosilane preparation.Related Products of 1762-34-1.

Cross-electrophile C-Si coupling has emerged as a promising tool for the construction of organosilanes, but the potential of this method remains largely unexplored. Herein, we report a C(sp3)-Si coupling of unactivated alkyl bromides with vinyl chlorosilanes. The reaction proceeds under mild conditions, and it offers a new approach to alkylsilanes. Functionalities such as Grignard-sensitive groups (e.g., acid, amide, alc., ketone, and ester), acid-sensitive groups (e.g., ketal and THP protection), alkyl fluoride and chloride, aryl bromide, alkyl tosylate and mesylate, silyl ether, and amine were tolerated. Incorporation of the -Si(vinyl)R2 moiety into complex mols. and the immobilization of a glass surface by formed organosilanes were demonstrated.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Some scientific research tips on 1762-34-1

Compound(1762-34-1)Application In Synthesis of 5,5′-Dimethyl-2,2′-bipyridine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Application In Synthesis of 5,5′-Dimethyl-2,2′-bipyridine. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5,5′-Dimethyl-2,2′-bipyridine, is researched, Molecular C12H12N2, CAS is 1762-34-1, about Chemical sensors based on nano-sized lanthanide-grafted periodic mesoporous organosilica hybrid materials. Author is Kaczmarek, Anna M.; Van Der Voort, Pascal.

In this work authors introduce the use of nano-sized (50-70 nm) lanthanide-grafted periodic mesoporous organosilicas for both metal ion sensing and solvent sensing. For this study a PMO constructed from the N,N-bis(trimethoxysilylpropyl)-2,6-pyridine dicarboxamide linker and tetra-Et orthosilicate (at a 5 : 95 ratio) was employed. This material was grafted with Eu3+, Tb3+ or a mixture of Eu3+-Tb3+ chloride salts to obtain strongly emitting nano-sized luminescence materials. To further enhance the luminescence properties of the materials two different co-ligands were used – 1,10-phenanthroline (phen) and 5,5′-dimethyl-2,2′-dipyridyl (bpy). The luminescence properties of the developed series of hybrid materials were studied in detail in the solid-state and after dispersing in water. The materials were investigated for their use as ion sensors, with the Eu3+ and Tb3+ phen and bpy co-grafted materials showing selective “”turn on”” fluorescence for Pb2+ and Cr3+ ions (at a 10 ppm concentration of the ions). The Eu3+-Tb3+ co-grafted materials showed solvatochromism and could be used as a solvent sensor to distinguish between protic and aprotic solvents.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Sources of common compounds: 1762-34-1

Compound(1762-34-1)Computed Properties of C12H12N2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Zou, Guo-Dong; Gong, Liao-Kuo; Liu, Li; Zhang, Qian; Zhao, Xiang-Hua published the article 《Two low-dimensional transition metal coordination polymers constructed from thiophene-2,5-dicarboxylic acid and N/O-donor ligands: Syntheses, structures and magnetic property》. Keywords: thiophenedicarboxylic acid transition metal coordination polymer preparation structure magnetic.They researched the compound: 5,5′-Dimethyl-2,2′-bipyridine( cas:1762-34-1 ).Computed Properties of C12H12N2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1762-34-1) here.

Two low-dimensional transition metal coordination polymers (CPs), namely, Co(TDC)(Hdmea)2 (1), [Mn(TDC)(5,5′-dmbpy)(H2O)]n (2) (H2TDC = thiophene-2,5-dicarboxylic acid, Hdmea = N,N-dimethylethanolamine, 5,5′-dmbpy = 5,5′-dimethyl-2,2′-dipyridyl) have been synthesized and characterized. Compound 1 which is the first coordination compound containing the H2TDC and chelating Hdmea ligands so far features an isolated structure containing the centrosym. dinuclear [Co(TDC)(Hdmea)2]2 unit. Notably, the imidazole ligand as one of the reactants is not incorporated into the final structure of compound 1, but it is important to obtain the single crystals suitable for single-crystal X-ray diffraction anal. Compound 2 possesses a one-dimensional (1D) zigzag chain based on the [Mn(TDC)(5,5′-dmbpy)(H2O)] building unit. In addition, the magnetic property of compound 2 is investigated.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Introduction of a new synthetic route about 1762-34-1

Compound(1762-34-1)Category: benzodioxans received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5,5′-Dimethyl-2,2′-bipyridine(SMILESS: CC1=CN=C(C=C1)C1=NC=C(C)C=C1,cas:1762-34-1) is researched.Formula: C7H6FNO2. The article 《Bipyridine-Directed Syntheses of Uranyl Compounds Containing Semirigid Dicarboxylate Linkers: Diversity and Consistency in Uranyl Speciation》 in relation to this compound, is published in Inorganic Chemistry. Let’s take a look at the latest research on this compound (cas:1762-34-1).

Bipyridine organic bases are beneficial to the synthesis of novel uranyl-organic hybrid materials, but the relationship between their mol. structures and specific roles as structure-directing agents, especially for the semirigid dicarboxylate systems, is still unclear. Here we demonstrate how the bipyridine ligands direct the coordination assembly of uranyl-organic compounds with a semirigid dicarboxylate linker, 4,4′-dicarboxybiphenyl sulfone (H2dbsf), by utilizing a series of bipyridine ligands, 1,10-phenanthroline (phen), 2,2′-bipyridine (2,2′-bpy), 5,5′-dimethylbipyridine (5,5′-dmbpy), 4,4′-bipyridine (4,4′-bpy), or 1,3-di(4-pyridyl)propane (bpp). Under hydrothermal conditions, eight uranyl-organic coordination polymers (UCPs), four of which [[UO2(dbsf)(phen)] (1), [UO2(dbsf)(phen)]·H2O (1′), [U4O10(dbsf)3]2[H2bpp]2 (6), and [U4O10(dbsf)3]2[H2bpp] (6′)] were reported previously, were synthesized and divided into two types based on the chelate or template effect of these bipyridine ligands. 1, 1′, [UO2(dbsf)(2,2′-bpy)] (2), and [(UO2)2(dbsf)2(5,5′-dmbpy)2] (3) are springlike triple helixes with bipyridine ligands (phen, 2,2′-bpy, or 5,5′-dmbpy) as chelate ligands, while [U4O10(dbsf)3][H2(4,4′-bpy)] (4), [U4O10(dbsf)3]2[H(4,4′-bpy)]2[Ni(H2O)6] (5), 6, and 6′ are tetranuclear uranyl-mediated 2-fold-interpenetrating networks with 4,4′-bpy or bpp as template ligands and charge-balancing agents. The participation or not in uranyl coordination of different bipyridine ligands promotes not only diversity in uranyl speciation and final topol. structures among different classes of organic bases but also consistency for the same types of bipyridine ligands, which thus endows the possibility of the rational design of UCPs based on semirigid dicarboxylate ligands with the aid of cautiously selected bipyridine ligands.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Interesting scientific research on 1799971-34-8

Compound(1799971-34-8)Synthetic Route of C10H18N2O3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate), if you are interested, you can check out my other related articles.

Synthetic Route of C10H18N2O3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate, is researched, Molecular C10H18N2O3, CAS is 1799971-34-8, about Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists. Author is Rudolph, Dale A.; Alcazar, Jesus; Ameriks, Michael K.; Anton, Ana Belen; Ao, Hong; Bonaventure, Pascal; Carruthers, Nicholas I.; Chrovian, Christa C.; De Angelis, Meri; Lord, Brian; Rech, Jason C.; Wang, Qi; Bhattacharya, Anindya; Andres, Jose Ignacio; Letavic, Michael A..

The optimization efforts that led to a novel series of Me substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones that are potent rat and human P2X7 antagonists are described. These efforts resulted in the discovery of compounds with good drug-like properties that are capable of high P2X7 receptor occupancy in rat following oral administration, including compounds I (P2X7 IC50 = 7.7 nM) and II (P2X7 IC50 = 7.7 nM). These compounds are expected to be useful tools for characterizing the effects of P2X7 antagonism in models of depression and epilepsy, and several of the compounds prepared are candidates for effective P2X7 PET tracers.

Compound(1799971-34-8)Synthetic Route of C10H18N2O3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate), if you are interested, you can check out my other related articles.

Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Simple exploration of 1762-34-1

Compound(1762-34-1)Safety of 5,5′-Dimethyl-2,2′-bipyridine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1762-34-1, is researched, SMILESS is CC1=CN=C(C=C1)C1=NC=C(C)C=C1, Molecular C12H12N2Journal, Article, Dalton Transactions called A sensitive photoluminescent chemosensor for cyanide in water based on a zinc coordination polymer bearing ditert-butyl-bipyridine, Author is Rosales-Vazquez, Luis D.; Valdes-Garcia, Josue; Bazany-Rodriguez, Ivan J.; German-Acacio, Juan M.; Martinez-Otero, Diego; Vilchis-Nestor, Alfredo R.; Morales-Luckie, Raul; Sanchez-Mendieta, Victor; Dorazco-Gonzalez, Alejandro, the main research direction is photoluminescent chemosensor cyanide zinc coordination polymer ditert butyl bipyridine.Safety of 5,5′-Dimethyl-2,2′-bipyridine.

Sensitive and direct sensing of cyanide in buffered aqueous solutions at pH = 7.0 by three new blue photoluminescent zinc-1,4-cyclohexanedicarboxylato coordination polymers bearing di-alkyl-2,2′-bipyridines has been achieved. Specifically, a Zn-polymer with the general formula: {[Zn2(H2O)2(e,a-cis-1,4-chdc)2(4,4′-dtbb)2]·7H2O}n, (1,4-chdc = 1,4-cyclohexanedicarboxylato and 4,4′-dtbb = 4,4′-ditert-butyl-2,2′-bipyridine) has been synthesized in high yield and studied as a luminescent chemosensor for halides, pseudohalides and a series of oxyanions in neutral water. CN- ions can be quant. detected by this polymer based on complete quenching (λem = 434 nm) in the sub-micromolar concentration range with a pronounced selectivity over common anions such as acetate, bromide and iodide. The quenching response (KSV = 9.7(±0.2) × 104 M-1) by the addition of CN- was also observed in the presence of typical interfering anions with a very low detection limit of 0.9μmol L-1 in buffered water at pH = 7.0. On the basis of the crystal structure and solid state CPMAS 13C-NMR correlation and 1H NMR, IR-ATR, MS-ESI(+) and SEM-EDS experiments, the optical change is attributed to the efficient release of its corresponding ditert-butyl-bipyridine, with the simultaneous formation of a zinc cyanide complex. The CPMAS 13C-NMR spectrum of the coordination polymer is consistent with the symmetry of the crystal structure. The use of flexible coordination polymers as fluorescent sensors for fast and selective detection of cyanide ions in pure aqueous solutions has been unexplored until now.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Introduction of a new synthetic route about 1762-34-1

Compound(1762-34-1)Formula: C12H12N2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A series of lanthanide complexes with 2-fluorobenzoic acid and 5,5′-dimethyl-2,2′-bipyridine: Synthesis, supramolecular structures, spectroscopy and thermal behaviour, published in 2021-08-31, which mentions a compound: 1762-34-1, mainly applied to lanthanide fluorobenzoate dimethylbipyridine supramol preparation crystal mol structure stability; thermal stability fluorescence lanthanide fluorobenzoate dimethylbipyridine supramol complex, Formula: C12H12N2.

A family of lanthanide-based self-assembling complexes constructed from 2-fluorobenzoic acid and 5,5′-dimethyl-2,2′-bipyridine have been successfully fabricated via conventional synthesis, namely, [Ln(2-FBA)3(5,5′-DM-2,2′-bipy)]2 (2-FBA = 2-fluorobenzoate, 5,5′-DM-2,2′-bipy = 5,5′-dimethyl-2,2′-bipyridine, Ln = La (1), Pr (2), Nd (3), Sm (4), Gd (5), Dy (6), Ho (7), Er (8)). The obtained complexes are investigated by elemental anal., IR spectra, Raman spectra and single-crystal x-ray diffraction. Crystallog. results exhibit that each Ln3+ ion of them is located in a distorted Muffin coordination sphere finished by seven oxygen atoms of 2-FBA ligands and two nitrogen atoms of 5,5′-DM-2,2′-bipy ligand. Interestingly, although complexes 1-6 and 7-8 have the same formula unit, the differences in hydrogen bond interactions lead to different supramol. structures. Besides, the thermal decomposition mechanism of the complexes has been studied by TG/DSC-FTIR technol. The results show that these complexes are thermally stable up to 450 K. In addition, complexes 4 and 6 both exhibit the characteristic fluorescence of lanthanide ions, i.e., complex 4 exhibits characteristic 4G5/2→6HJ/2 (J = 5, 7, 9) transitions, and complex 6 shows characteristic 4F9/2→6HJ/2 (J = 15, 13) transitions.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem

Extracurricular laboratory: Synthetic route of 1762-34-1

Compound(1762-34-1)COA of Formula: C12H12N2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5,5′-Dimethyl-2,2′-bipyridine), if you are interested, you can check out my other related articles.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1762-34-1, is researched, SMILESS is CC1=CN=C(C=C1)C1=NC=C(C)C=C1, Molecular C12H12N2Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Inorganic Biochemistry called Ru(II)/N-N/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (N-N = diimine or diamine), Author is Ribeiro, Gabriel H.; Colina-Vegas, Legna; Clavijo, Juan C. T.; Ellena, Javier; Cominetti, Marcia R.; Batista, Alzir A., the main research direction is ruthenium dipyridylamine diimine complex preparation crystal structure; electrochem antitumor activity lipophilicity ruthenium dipyridylamine diimine complex; DNA HSA binding ruthenium dipyridylamine diimine complex.COA of Formula: C12H12N2.

The rational design of anticancer agents that acts in specific biol. targets is one of the most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new ruthenium(II) compounds with good cytotoxicity against tumor cells, a series of new complexes of general formula [RuCl(PPh3)(Hdpa)(N-N)]Cl [PPh3 = triphenylphosphine, N-N = 2,2′-dipyridylamine (Hdpa) (1), 1,2-diaminoethane (en) (2), 2,2′-bipyridine (bipy) (3), 5,5′-dimethyl-2,2′-bipyridine (dmbipy) (4), 1,10-phenanthroline (phen) (5) and 4,7-diphenyl-1,10-phenanthroline (dphphen) (6)] were synthesized. The complexes were characterized by elemental anal. and spectroscopic techniques (IR, UV/Visible, and 1D and 2D NMR) and three of their x-ray structures were determined: [RuCl(PPh3)(Hdpa)2]Cl, [RuCl(PPh3)(Hdpa)(en)]Cl and [RuCl(PPh3)(Hdpa)(dmbipy)]Cl. All the complexes are more cytotoxic against the cancer cell line than against the non-tumor cell line, highlighting complexes 1 and 5, which have an index selectivity of 18 and 15, resp. The binding constants of compounds 1-6 with human serum albumin (HSA) were determined by tryptophan fluorescence quenching, indicating moderate to strong interactions. The binding mode of the complexes to calf thymus (CT) DNA was explored by several techniques, which reveal that only the dphphen compound 6 causes distortions in the secondary and tertiary structures of DNA. The nature of the N-N co-ligand and the presence of the PPh3 and Hdpa ligands are features that can influence the binding affinity of the complexes by the biomols. and in the cytotoxic activity of the complexes. Overall, the complexes with diimine co-ligand are much more cytotoxic than compound 2 with the aliphatic diamine.

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Reference:
Benzodioxan,
1,4-Benzodioxane | C8H8O2 – PubChem