Day: February 14, 2022

An article Biomass-derived carbon-supported Ni catalyst: an effective heterogeneous non-noble metal catalyst for the hydrogenation of nitro compounds WOS:000507993700002 published article about CHEMOSELECTIVE HYDROGENATION; SELECTIVE HYDROGENATION; PD NANOPARTICLES; NITROARENES; REDUCTION; PATHWAY in [Tang, Qingjie; Yuan, Ziliang; Jin, Shiwei; Yao, Kaiyue; Yang, Hanmin; Chi, Quan; Liu, Bing] South Cent Univ Nationalities, Minist Educ, Key Lab Catalysis & Mat Sci, Wuhan 430074, Peoples R China in 2020.0, Cited 29.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

There has been a great deal of attention to the development of heterogeneous non-noble metal catalysts for the selective and mild hydrogenation of nitro compounds into primary amines. Herein, a biomass-derived carbon material supported Ni catalyst (Ni/C) was facilely prepared by a one-pot pyrolysis process, and the as-prepared Ni/C catalyst demonstrated a high catalytic activity for the hydrogenation of nitro compounds into primary amines at room temperature. The Ni/C catalyst not only demonstrated a high catalytic activity but also showed a good tolerance to other functional groups. Structurally diverse primary amines were achieved in yields from 92% to 99% within a few hours at room temperature under 5 bar H-2. Furthermore, the Ni/C catalyst showed good reusability without the loss of its activity.

Name: 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Tang, QJ; Yuan, ZL; Jin, SW; Yao, KY; Yang, HM; Chi, Q; Liu, B or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M in [Massolo, Elisabetta; Pirola, Margherita; Puglisi, Alessandra; Rossi, Sergio; Benaglia, Maurizio] Univ Milan, Dipartimento Chim, Via Golgi 19, I-20133 Milan, Italy published A one pot protocol to convert nitro-arenes into N-aryl amides in 2020, Cited 42. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A two-step one pot, experimentally simple protocol, based on readily available and inexpensive reagents allowed the conversion of nitro-arenes directly to N-aryl amides. A metal-free reduction of the nitro group, mediated by trichlorosilane, followed by the addition of an anhydride afforded the corresponding N-aryl carboxyamide, that was isolated after a simple aqueous work up in good-excellent yields. When the methodology was applied to the reaction with gamma-butyrolactone, the desired N-aryl butanamide derivative was obtained, featuring a chlorine atom at the gamma-position, a functionalized handle that can be used for further synthetic manipulation of the reaction product. Such an intermediate has already been employed as a key advanced precursor of pharmaceutically active compounds.

HPLC of Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Massolo, E; Pirola, M; Puglisi, A; Rossi, S; Benaglia, M or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about ONE-POT SYNTHESIS; CONJUGATE ADDITION; ALPHA-METHYLATION; KETONES; ALCOHOLS; AMINES; SESQUITERPENOIDS; ALKYLATION; REACTIVITY; EFFICIENT, Saw an article supported by the Science & Engineering Research Board (SERB), New DelhiDepartment of Science & Technology (India)Science Engineering Research Board (SERB), India [EMR/2017/000620]; Department of Atomic Energy (DAE)Department of Atomic Energy (DAE); CSIRCouncil of Scientific & Industrial Research (CSIR) – India; DSTDepartment of Science & Technology (India). Name: 1-(4-Nitrophenyl)ethanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Biswal, P; Samser, S; Nayak, P; Chandrasekhar, V; Venkatasubbaiah, K. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A novel cobalt(II)porphyrin-mediated acceptorless dehydrogenation of methanol is reported for the first time. This methodology has been applied for the coupling of a variety of ketones with methanol to produce 1,5-diketones along with H-2 and H2O as the environment friendly byproducts. This paradigm was also demonstrated for a one-pot synthesis of substituted pyridines using a sequential addition protocol where the 1,5-diketones were generated in situ. From many experiments including those involving deuterium labeling, it is proposed that protonated cobalt(II)-porphyrin methoxide complex acts as an intermediate to generate formaldehyde along with a metal hydride.

Name: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about H BOND ACTIVATION; SUPERCRITICAL CARBON-DIOXIDE; DIRECTING GROUP; O BOND; INTERNAL OXIDANT; POLYETHYLENE-GLYCOL; IONIC LIQUIDS; EFFICIENT SYNTHESIS; IRIDIUM COMPLEXES; ORGANIC-SYNTHESIS, Saw an article supported by the University Grant Commission (UGC), New Delhi, IndiaUniversity Grants Commission, India [F.25-1/2014-15(BSR)/F.7-227/2009]. Quality Control of 1-(4-Nitrophenyl)ethanone. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Deshmukh, DS; Gangwar, N; Bhanage, BM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Herein, we report an atom-efficient, rapid, green, and sustainable approach to synthesize isoquinolines and isoquinolinones using a homogeneous recyclable ruthenium catalyst in PEG Media assisted by microwave energy. Dibenzoylhydrazine was used for C-H/N-N activation reactions for the first time in combination with ketazine as oxidizing directing groups for annulation reactions with internal alkynes. The developed protocol is environmentally benign due to significantly shortened times with an easy extraction method, higher atom economy, external oxidant and silver or antimony salt free conditions, applicability to a gram scale synthesis, use of biodegradable solvent and wide substrate scope with higher product yields. Moreover, it is worth noting that the established methodology allowed reuse of the catalytic system for up to five successive runs with minimal loss in activity.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Design, synthesis and bioevaluation of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide derivatives as novel xanthine oxidase inhibitors WOS:000463339500006 published article about BIOLOGICAL EVALUATION; ACID-DERIVATIVES; HYPERURICEMIA in [Zhang, Lichao; Wang, Sibo; Bao, Kai] Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Liaoning, Peoples R China; [Yang, Mingzheng; Guan, Qi] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Liaoning, Peoples R China; [Shi, Ailong; Wang, He; Zhang, Weige] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China in 2019.0, Cited 28.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. HPLC of Formula: C8H7NO3

In view of expanding the structure activity relationship of xanthine oxidase inhibitors, a series of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide/carboxylic acid derivatives were designed by molecular docking and synthesized. All the target compounds were evaluated for their in vitro XO inhibition by using febuxostat and allopurinol as the standard controls. Most of the hydrazide derivatives exhibited potency levels in the micromolar range. From the view of docking study, hydrazide derivatives bind to the active site of XO through a novel interaction mode, which is different from that of febuxostat bearing a carboxyl group. The most promising compound 8b was further subjected to kinetic analysis to deduce their modes of inhibition.

Welcome to talk about 100-19-6, If you have any questions, you can contact Zhang, LC; Wang, SB; Yang, MZ; Shi, AL; Wang, H; Guan, Q; Bao, K; Zhang, WG or send Email.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Adole, VA; More, RA; Jagdale, BS; Pawar, TB; Chobe, SS in WILEY-V C H VERLAG GMBH published article about POLYETHYLENE-GLYCOL; BIOLOGICAL EVALUATION; THIAZOLE DERIVATIVES; ORGANIC-SYNTHESIS; IN-VITRO; SOLVENT; PEG in [Adole, Vishnu A.; Jagdale, Bapu S.; Pawar, Thansing B.; Chobe, Santosh S.] Savitribai Phule Pune Univ, Res Ctr Chem, Loknete Vyankatrao Hiray Arts Sci & Commerce Coll, Pune 422003, Nashik, India; [More, Rahul A.] Swami Ramanand Teerth Marathwada Univ, Dept Microbiol, Dayanand Sci Coll, Nanded Latur 413512, India in 2020.0, Cited 36.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

In the present investigation, an alluring green PEG-400 mediated one-pot synthesis of novel 2-(2-hydrazinyl)thiazole derivatives from 1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one has been unveiled via a novel synthetic pathway. The application of PEG in organic reactions as a reaction media is one of the fantastic tools of green chemistry as reactions can be carried out under generous conditions limiting environmental peril and chemical waste. PEG-400 is recognized as a low-cost, non-flammable, environmentally benign, recyclable, and richly available green solvent. A series of novel 2-(2-hydrazineyl)thiazole derivatives have been synthesized in good to excellent yield by using the green capability of PEG-400 solvent. These newly synthesized compounds were tested for their antimicrobial and antioxidant activities. The results revealed that these compounds show good activities compared with the standard. Additionally, all the synthesized compounds exhibit negligible cytotoxicity as compared to the positive control. The structures of all novel compounds reported herein are established using FT-IR, H-1 NMR, C-13 NMR, D2O exchange experiment and HRMS techniques.

Welcome to talk about 100-19-6, If you have any questions, you can contact Adole, VA; More, RA; Jagdale, BS; Pawar, TB; Chobe, SS or send Email.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Fabrication and Catalytic Properties of Films Based on Metal Ion-ligand Interaction between K2PdCl4 and 3-Amino-3-(4-pyridinyl)-propionitrile WOS:000520019700017 published article about HOMOGENEOUS CATALYSIS; HETEROGENEOUS CATALYSTS; HYDROGENATION; PD; REDUCTION; NANOPARTICLES; NITROARENES; RECOVERY; LAYER; MONODISPERSE in [Chen Yan-Ning; Li Jing-Jun; Yang Wei-Guang] Fuzhou Univ, Coll Chem, Fuzhou 350002, Peoples R China; [Chen Yan-Ning; Li Jing-Jun; Yang Wei-Guang; Gao Shui-Ying] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China in 2020.0, Cited 34.0. Computed Properties of C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

This work presents a highly active and reusable heterogeneous film catalytic assembly for hydrogenation reduction of aromatic nitro compounds. The multilayer structures of PEI-(K2PdCl4-P1)(n)-film (PEI = polyethylenmine, P1 = 3-amino-3-(4-pyridinyl)-propionitrile) bound to quartz slides were fabricated by layer-by-layer (LbL) self-assembly method. Various characterization techniques including X-ray photoelectron spectroscopy (XPS), inductively coupled plasma OES spectrometer (ICP), UV-vis spectroscopy and atomic force microscopy (AFM) were employed to reveal the growth process of the resulting LbL multilayers in detail. Subsequent in situ reduction by H-2 produced Pd nanoparticles embedded in such films were used as catalyst for the hydrogenation of nitroarenes. The catalytic performance test shows that the thin film catalyst can be applied to the hydrogenation reaction of various substituted nitroaromatics, and exhibits good catalytic activity and good catalyst stability. It is worth mentioning that our catalytic films can be easily removed from the reaction system in any time during the reaction, and the catalytic activity could be fully recovered when reused directly in another catalytic cycle for five times.

Computed Properties of C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Kovar, SE; Fourman, C; Kinstedt, C; Williams, B; Morris, C; Cho, KJ; Ketcha, DM in PERGAMON-ELSEVIER SCIENCE LTD published article about BIOLOGICAL EVALUATION; PKC-DELTA; PROTEIN; ANTICANCER; CANCER; TRAFFICKING; ASSOCIATION; DERIVATIVES; EXPRESSION; MUTATIONS in [Kovar, Sarah E.; Cho, Kwang-jin] Wright State Univ, Dept Biochem & Mol Biol, Dayton, OH 45435 USA; [Fourman, Cody; Kinstedt, Christine; Williams, Brandon; Morris, Christopher; Ketcha, Daniel M.] Wright State Univ, Dept Chem, Dayton, OH 45435 USA in 2020.0, Cited 44.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Ras proteins are small GTPases which regulate cellular proliferation, differentiation, and apoptosis. Constitutively active mutant Ras are expressed in similar to 15-20% human cancers, and K-Ras mutations account for similar to 85% of all Ras mutations. Despite the significance of Ras proteins in refractory cancers, there is no anti-Ras drug available in clinic. Since K-Ras must interact with the plasma membrane (PM) for biological activity, inhibition of the K-Ras/PM interaction is a tractable approach to block oncogenic K-Ras activity. Here, we discovered chalcones 1 and 8 exhibit anti-K-Ras activity, and show that the compounds mislocalize K-Ras from the PM and block oncogenic K-Ras signal output. Also, 1 inhibits the growth of K-Ras-driven human cancer cells. Our data suggest that 1 could be a promising starting point for developing anti-K-Ras cancer drug.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Ding, YX; Ma, RC; Hider, RC; Ma, YM in [Ding, Yuxin; Ma, Renchao; Ma, Yongmin] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China; [Ding, Yuxin; Ma, Yongmin] Zhejiang Chinese Med Univ, Sch Pharmaceut Sci, Hangzhou 310053, Peoples R China; [Hider, Robert C.] Kings Coll London, Inst Pharmaceut Sci, Franklin Wilkins Bldg,Stamford St, London SE1 9NH, England published Acid-Catalyzed Pseudo Five-Component Annulation for a General One-Pot Synthesis of 2,4,6-Triaryl Pyrimidines in 2020.0, Cited 65.0. Safety of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A facile and general synthesis of 2,4,6-triaryl pyrimidines has been developed. It involves a one-pot [2+1+1+1+1] pseudo five-component annulation of one methyl ketone, two aldehydes and two NH4OAc catalyzed by TfOH. One C-C and four C-N bonds are formed during the oxidative annulation process. The reaction shows good tolerance of many important functional groups in air and produces only water as the coproduct, making this methodology a highly versatile alternative to the existing methods for structuring pyrimidine framework.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis, Antiproliferative and Cytotoxic Activities, DNA Binding Features and Molecular Docking Study of Novel Enamine Derivatives published in 2020.0. Category: benzodioxans, Reprint Addresses Gurdere, MB (corresponding author), Tokat Gaziosmanpasa Univ, Fac Arts & Sci, Dept Chem, TR-60250 Tokat, Turkey.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Novel enamine derivatives were synthesized from the reaction of lactone and chalcones and their antiproliferative and cytotoxic activities against six cancer cell lines (e. g., HeLa, HT29, A549, MCF7, PC3 and Hep3B) and one normal cell lines (e. g., FL) were investigated along with their mode of interactions with CT-DNA. Most of the enamine derivatives with IC(50)values of 86-168 mu M demonstrated much stronger antiproliferative activity than the starting molecules against the cancer cells. While, among the enamine derivatives, four compounds displayed higher cytotoxic potency than the control drugs (5-fluorouracil and cisplatin) against the Hep3B cell lines, these compounds did not exhibit any significant toxicity against normal cells, FL. The UV/VIS spectral data suggest that eight compounds cause hypochromism with a slight bathochromic shift (similar to 6 nm), indicating that they bind to the DNA by way of an intercalative or minor groove binding mode. The binding constants of the compounds are in the range of 0.1×103 M-1-2.3×104 M-1. The antiproliferative activity of studied enamine derivatives could possibly be due to their DNA binding as well as their cytotoxic properties. In addition to these assays, the chalcones and enamine derivatives were investigated by molecular docking to calculate the synergistic effect of antiproliferative activities against six human cancer cell lines.

Category: benzodioxans. Welcome to talk about 100-19-6, If you have any questions, you can contact Gurdere, MB; Aydin, A; Yencilek, B; Erturk, F; Ozbek, O; Erkan, S; Budak, Y; Ceylan, M or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem