Day: January 7, 2022

COA of Formula: C8H7NO3. In 2019.0 EUR J MED CHEM published article about SELECTIVE INHIBITORS; DERIVATIVES; DESIGN; POTENT; DISCOVERY; DOCKING; HYBRIDS; MOIETY; AGENTS in [Moi, Davide; Balboni, Gianfranco; Onnis, Valentina] Univ Cagliari, Unit Pharmaceut Pharmacol & Nutraceut Sci, Dept Life & Environm Sci, Via Osped 72, I-09124 Cagliari, Italy; [Nocentini, Alessio; Supuran, Claudiu T.] Univ Firenze, Pharmaceut & Nutraceut Sect, Dept NEUROFARBA, Via Ugo Schiff 6, I-50019 Florence, Italy; [Deplano, Alessandro] Pharmacelera, Placa Pau Vila 1,Sect 1,Edificio Palau Mar, Barcelona 08039, Spain in 2019.0, Cited 64.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), hCA I, II, IX, and XII. The reported derivatives, obtained by a sulfamoylation reaction of the corresponding phenolic precursors, bear 3,5-diarylpyrazoline moieties as spacers between the benzenesulfamate fragment which binds the zinc ion from the active site, and the tail of the inhibitor. Pyrazolines are biologically privileged scaffolds, endowed with versatile biological activity, such as an anti-proliferative action. The derivatives were tested for the inhibition of the cytosolic, hCA I and II (off target isoforms) and the trans-membrane, tumor-associated hCA IX and XII enzymes (anticancer drug targets). Generally, hCA I was not effectively inhibited, whereas many low nanomolar inhibitors were evidenced against hCA II (KIs in the range of 0.42-90.1 nM), IX (KIs in the range of 0.72-63.6 nM), and XII (KIs in the range of 0.88-85.2 nM). The best substitution fragments at the pyrazoline ring included for CA it a 4-sulfamic group on the 3-aryl and halogens on the 5-aryl or a methoxy group on the 3-aryl and a 4-sulfamate group on the 5-aryl; for CA IX and CA XII they included the sulfamic group on the 3- or 4-position of the 5-aryl and an electronwithdrawing group on the 4-postion of the 3-aryl ring. (C) 2019 Elsevier Masson SAS. All rights reserved.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. COA of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Wu, ZT; Du, SZ; Gao, GR; Yang, WK; Yang, XY; Huang, HZ; Chang, MX in ROYAL SOC CHEMISTRY published article about ALKYL-ARYL KETONES; IR-F-BINAPHANE; ENANTIOSELECTIVE HYDROGENATION; IDENTIFICATION; SALTS in [Wu, Zitong; Du, Shaozhi; Yang, Wenkun; Yang, Xiongyu; Huang, Haizhou; Chang, Mingxin] Northwest A&F Univ, Coll Chem & Pharm, Shanxi Key Lab Nat Prod & Chem Biol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China; [Gao, Guorui] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Univ Shandong, Coll Chem Chem Engn & Mat Sci, 88 Wenhuadong Rd, Jinan 250014, Shandong, Peoples R China in 2019.0, Cited 56.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The secondary amine participating asymmetric reductive amination remains an unsolved problem in organic synthesis. Here we show for the first time that secondary amines are capable of effectively serving as N-sources in direct asymmetric reductive amination to afford corresponding tertiary chiral amines with the help of a selected additive set under mild conditions (0-25 degrees C). The applied chiral phosphoramidite ligands are readily prepared from BINOL and easily modified. Compared with common tertiary chiral amine synthetic methods, this procedure is much more concise and scalable, as exemplified by the facile synthesis of rivastigmine and N-methyl-1-phenylethanamine.

Welcome to talk about 100-19-6, If you have any questions, you can contact Wu, ZT; Du, SZ; Gao, GR; Yang, WK; Yang, XY; Huang, HZ; Chang, MX or send Email.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Design, Sonosynthesis, Quantum-Chemical Calculations, and Evaluation of New Mono- and Bis-pyridine Dicarbonitriles as Antiproliferative Agents WOS:000523280700001 published article about FLUORESCENCE; INHIBITOR; SERIES; ACID in [Arafa, Wael Abdelgayd Ahmed; Hussein, Modather F.] Jouf Univ, Coll Sci, Chem Dept, POB 2014, Sakaka, Aljouf, Saudi Arabia; [Arafa, Wael Abdelgayd Ahmed] Fayoum Univ, Fac Sci, Chem Dept, POB 63514, Fayoum City, Egypt; [Hussein, Modather F.] Al Azhar Univ, Fac Sci, Chem Dept, Asyut Branch, Cairo, Egypt in 2020.0, Cited 49.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Computed Properties of C8H7NO3

i Summary of main observation and conclusion A highly efficient, simple, and clean single-step sonosynthetic procedure has been sophisticated for assembling new series of mono- and bis-pyridine dicarbonitriles from ketones, HCl, and tetracyanoethylene. The presented protocol is applicable for the preparation of a broad range of uniquely substituted pyridine dicarbonitriles and seems to be superior in comparison with other previously reported methods. The antiproliferative impact of the newly synthesized derivatives was screened towards three representative cancer cell lines (MCF-7, A549, and HCT116). Most of the evaluated derivatives showed a moderate to excellent anti-proliferative activity towards the selected cell lines. Of these, compounds 4h, 4k, 10, 12a, and 12b showed both potent anticancer activity (IC50<10 mu M) and lower cytotoxic effect (IC50 > 58 mu M) on non-tumorigenic cells (MCF-10A and NCM460), suggesting their promising potential to be lead molecules for future antitumor drug discovery. The structure-activity relationships have been also discussed. Moreover, quantum chemical studies based on Density Functional Theory (DFT) of the synthesized compounds were investigated and found to be consistent with the in vitro inhibitory activities.

Computed Properties of C8H7NO3. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. Lin, JS; Li, TT; Jiao, GY; Gu, QS; Cheng, JT; Lv, L; Liu, XY in [Lin, Jin-Shun] Tsinghua Univ, Key Lab Chem Biol, State Key Lab Chem Oncogen, Grad Sch Shenzhen, Shenzhen 518055, Peoples R China; [Lin, Jin-Shun] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China; [Lin, Jin-Shun; Li, Tao-Tao; Jiao, Guan-Yuan; Gu, Qiang-Shuai; Cheng, Jiang-Tao; Lv, Ling; Liu, Xin-Yuan] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China; [Lin, Jin-Shun; Li, Tao-Tao; Jiao, Guan-Yuan; Cheng, Jiang-Tao; Lv, Ling; Liu, Xin-Yuan] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China; [Gu, Qiang-Shuai] Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518055, Peoples R China published Chiral BrOnsted Acid Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes in 2019, Cited 71. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

The first highly efficient and practical chiral BrOnsted acid catalyzed dynamic kinetic asymmetric hydroamination (DyKAH) of racemic allenes and asymmetric hydroamination of unactivated dienes with both high E/Z selectivity and enantioselectivity are described herein. The transformation proceeds through a new catalytic asymmetric model involving a highly reactive pi-allylic carbocationic intermediate, generated from racemic allenes or dienes through a proton transfer mediated by an activating/directing thiourea group. This method affords expedient access to structurally diverse enantioenriched, potentially bioactive alkenyl-containing aza-heterocycles and bicyclic aza-heterocycles.

Welcome to talk about 86-29-3, If you have any questions, you can contact Lin, JS; Li, TT; Jiao, GY; Gu, QS; Cheng, JT; Lv, L; Liu, XY or send Email.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. Recently I am researching about H BOND ACTIVATION; POLYSTYRENE MICROSPHERES; HOLLOW MICROSPHERES; INTRAMOLECULAR HYDROALKOXYLATION; PROPARGYLIC ALCOHOLS; C-C; CYCLIZATION; COMPLEXES; FABRICATION; GENERATION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21776111, 21861039]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [JUSRP 51627B]; MOE SAFEA [B13025]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Ye, DD; Pan, L; Zhu, HY; Jin, L; Miao, HY; Wang, DW. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Modified polycyanostyrene and polynitrostyrene microspheres were designed and synthesized, which proved to be an effective carrier to prepare gold nanoparticles with pentazole gold as a catalyst precursor. The developed gold nanoparticles were characterized using scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray, X-ray power diffraction and X-ray photoelectron spectrometry. In addition, it was observed that this catalytic system successfully achieved application in the synthesis of cinnoline derivatives and hydration reactions in high yields. Mechanism investigation was conducted to better understand these transformations and catalyst systems. To the best of our knowledge, this is the first example of utilizing pentazole gold as the catalyst precursor and achieving catalytic applications.

Name: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. In 2019.0 EUR J ORG CHEM published article about ESTERS; HYDROBORATION; BORYLATION; ALKYNES; DIVERSIFICATION; CARBANIONS in [Kovalenko, Maksym; Yarmoliuk, Dmytro, V; Serhiichuk, Dmytro; Chernenko, Dania; Smyrnov, Vladyslav; Breslayskyi, Artur; Hryshchuk, Oleksandr, V; Kleban, Ihor; Tymtsunik, Andriy, V; Tolmachev, Andrey A.; Kuchkovska, Yuliya O.; Grygorenko, Oleksandr O.] Enamine Ltd, Chervonotkatska St 78, UA-02094 Kiev, Ukraine; [Yarmoliuk, Dmytro, V; Smyrnov, Vladyslav; Hryshchuk, Oleksandr, V; Tolmachev, Andrey A.; Kuchkovska, Yuliya O.; Grygorenko, Oleksandr O.] Tams Shevchenko Natl Univ Kyiv, Volodymyrska St 60, UA-01601 Kiev, Ukraine; [Kleban, Ihor; Rassukana, Yuliya] Natl Acad Sci Ukraine, Inst Organ Chem, Murmanska St 5, UA-02660 Kiev, Ukraine; [Chernenko, Dania; Rassukana, Yuliya; Tymtsunik, Andriy, V] Natl Tech Univ Ukraine, Igor Sikorsky Kyiv Polytech Inst, Prospect Perem 37, UA-03056 Kiev, Ukraine in 2019.0, Cited 50.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Preparation of 2,2-disubstituted and 2-monosubstituted alkenylboronic acid esters from aliphatic and aromatic ketones and aldehydes by the boron-Wittig olefination with bis[(pinacolato)boryl]methane was examined and applied on the multigram scale. The influence of the substrate steric and electronic features on the overall efficiency and stereochemical outcome of the reaction was studied. Additionally, a series of diversely functionalized (hetera)cycloalkylidenemethyl and (hetera)cycloalkyl boronic acid-derived building blocks was synthesized.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Kovalenko, M; Yarmoliuk, DV; Serhiichuk, D; Chernenko, D; Smyrnov, V; Breslayskyi, A; Hryshchuk, OV; Kleban, I; Rassukana, Y; Tymtsunik, AV; Tolmachev, AA; Kuchkovska, YO; Grygorenko, OO or concate me.. SDS of cas: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. In 2019.0 ACTA CRYSTALLOGR E published article about INTERMOLECULAR INTERACTIONS in [Wong, Qin Ai; Chia, Tze Shyang; Quah, Ching Kheng] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm 11800, Penang, Malaysia; [Kwong, Huey Chong] Univ Sains Malaysia, Sch Chem Sci, Usm 11800, Penang, Malaysia; [Kumar, C. S. Chidan] Visvesvaraya Technol Univ, Vidya Vikas Inst Engn & Technol, Dept Engn Chem, Alanahalli 570028, Mysuru, India; [Arafath, Md Azharul] Shahjalal Univ Sci & Technol, Dept Chem, Sylhet 3114, Bangladesh in 2019.0, Cited 19.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The molecular structure of the title chalcone derivative, C15H10FNO3, is nearly planar and the molecule adopts a trans configuration with respect to the C=C double bond. The nitro group is nearly coplanar with the attached benzene ring, which is nearly parallel to the second benzene ring. In the crystal, molecules are connected by pairs of weak intermolecular C-H center dot center dot center dot O hydrogen bonds into inversion dimers. The dimers are further linked by another C-H center dot center dot center dot O hydrogen bond and a C-H center dot center dot center dot F hydrogen bond into sheets parallel to (104). pi-pi interactions occur between the sheets, with a centroid-centroid distance of A 3.8860 (11) angstrom. Hirshfeld surface analysis was used to investigate and quantify the intermolecular interactions.

Welcome to talk about 100-19-6, If you have any questions, you can contact Wong, QA; Chia, TS; Kwong, HC; Kumar, CSC; Quah, CK; Arafath, MA or send Email.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Stable single-atom platinum catalyst trapped in carbon onion graphitic shells for improved chemoselective hydrogenation of nitroarenes WOS:000456710500043 published article about LIQUID-PHASE HYDROGENATION; TRANSITION-METAL CR; P-CHLORONITROBENZENE; NANOPARTICLES; CO; OXIDATION; EFFICIENT; MN; FE; NI in [Yan, Xiaoli; Duan, Pei; Li, Hai; Zhang, Haixia; Zhao, Min; Xu, Bingshe; Guo, Junjie] Taiyuan Univ Technol, Minist Educ, Key Lab Interface Sci & Engn Adv Mat, Taiyuan 030024, Shanxi, Peoples R China; [Zhang, Fengwei; Zhang, Xianming] Shanxi Univ, Inst Crystalline Mat, Taiyuan 030006, Shanxi, Peoples R China; [Pennycook, Stephen J.] Natl Univ Singapore, Dept Mat Sci & Engn, Singapore 117575, Singapore in 2019.0, Cited 40.0. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Supported platinum (Pt) catalysts present excellent chemoselectivity for a variety of hydrogenation reactions. Minimizing the use of such expensive catalysts while retaining their catalytic activities has been one of the most challenging topics in recent years. The construction of well dispersed, stable Pt single atom catalysts both increases the density of catalytically active sites while reducing Pt usage. Here we report the synthesis of Pt single atoms trapped in carbon onion graphitic shells by arc-discharge in aqueous solution. Such graphitic shells not only limit the chemical/thermal coarsening of Pt single atoms, but also enhance the conductivity for accelerating the penetration and exchange of ions and electrons during the catalytic process. Experimental results demonstrate that the Pt single atomcatalysts show superior performance and no detectable loss of activity and selectivity over 10 cycles (both remain >99%) for the hydrogenation of p-chloronitrobenzene. This novel atomically dispersed form of Pt catalyst is indicative of a new avenue towards efficient synthesis of single atom catalysts with improved performance. (C) 2018 Elsevier Ltd. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Yan, XL; Duan, P; Zhang, FW; Li, H; Zhang, HX; Zhao, M; Zhang, XM; Xu, BS; Pennycook, SJ; Guo, JJ or concate me.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Chen, SP; Jiang, PY; Wang, P; Pei, Y; Huang, HW; Xiao, FH; Deng, GJ in AMER CHEMICAL SOC published article about C-H FUNCTIONALIZATION; ONE-POT SYNTHESIS; EFFICIENT CONSTRUCTION; SUBSTITUTED CARBAZOLES; CLAUSINE-L; INDOLES; ANNULATION; ALKALOIDS; ACID; CYCLIZATION in [Chen, Shanping; Jiang, Pingyu; Wang, Pu; Pei, Yong; Huang, Huawen; Xiao, Fuhong; Deng, Guo-Jun] Xiangtan Univ, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat, Minist Educ,Coll Chem, Xiangtan 411105, Peoples R China in 2019.0, Cited 81.0. Product Details of 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A novel method was developed for the synthesis of substituted carbazoles from commercially available starting materials under metal-free conditions. This strategy involves a [1s,6s] sigmatropic shift step and introduces an electron-withdrawing ester substituent at the C2 position of the carbazole ring. The present protocol afforded the desired carbazole derivatives with good regioselectivity and well functional group tolerance. DFT calculations were carried out to support the reaction pathway.

Product Details of 100-19-6. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. Chai, GL; Sun, AQ; Zhai, D; Wang, J; Deng, WQ; Wong, HNC; Chang, JB in [Chai, Guo-Li; Sun, A-Qiang; Wang, Juan; Deng, Wei-Qiao; Wong, Henry N. C.; Chang, Junbiao] Henan Normal Univ, Sch Chem & Chem Engn, Henan Key Lab Organ Funct Mol & Drug Innovat, Xinxiang 453007, Henan, Peoples R China; [Zhai, Dong; Deng, Wei-Qiao] Shandong Univ, Inst Mol Sci & Engn, Qingdao 266237, Shandong, Peoples R China; [Wong, Henry N. C.] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China published Chiral Hydroxytetraphenylene-Catalyzed Asymmetric Conjugate Addition of Boronic Acids to Enones in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

(S)-2,15-Br-2-DHTP-catalyzed asymmetric conjugate addition of boronic acids to beta-trifluoromethyl alpha,beta-unsaturated ketones and enones was studied. The reaction afforded the corresponding Michael addition products in moderate to high yields with excellent enantioselectivities (up to 99:1 er). This catalytic system features mild reaction conditions, high efficiency, and tolerance to heteroarylboronic acids.

Computed Properties of C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Chai, GL; Sun, AQ; Zhai, D; Wang, J; Deng, WQ; Wong, HNC; Chang, JB or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem