Day: December 3, 2021

I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction published in 2020.0. Category: benzodioxans, Reprint Addresses Su, GY (corresponding author), Shandong Univ, Jinan Cent Hosp, Cheeloo Coll Med, Dept Cardiol, Jinan 250013, Shandong, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A facile synthesis of a group of novel thiazole-pyrazolone hybrids and their investigation for angiotensin-converting enzyme (ACE) inhibition are reported in this study. These compounds were synthesized using a well-known approach, based on the condensation of ethyl acetoacetate with thiazolylhydrazines, and characterized by various spectroscopic and analytical techniques. The entire set of compounds displayed a moderate-to-excellent inhibitory activity against ACE. In particular, compound4iwas found to be the most potent ACE inhibitor and was further studied for cardioprotective effects against isoproterenol (ISO)-induced myocardial infarction (MI) in rats. Compound4iimproved the cardiac function and prevented cardiac injury induced by ISO in Sprague Dawley rats. The levels of oxidative stress and proinflammatory cytokines were also restored to near normal by4ias compared with the ISO group. In the Western blot analysis, compound4iprevented mitochondrial apoptosis after MI by downregulating the expression of cleaved caspase-3 and Bax, with the upregulation of Bcl-2, as compared with the ISO group.

Category: benzodioxans. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Weber, S; Veiros, LF; Kirchner, K in WILEY-V C H VERLAG GMBH published article about MOLECULAR-ORBITAL METHODS; GAUSSIAN-TYPE BASIS; PRIMARY AMINES; SELECTIVE HYDROGENATION; EQUILIBRIUM GEOMETRIES; INSERTION REACTIONS; HYDROFORMYLATION; HYDROGENOLYSIS; APPROXIMATION; ALDEHYDES in [Weber, Stefan; Kirchner, Karl] Vienna Univ Technol, Inst Appl Synthet Chem, Getreidemarkt 9-163-AC, A-1060 Vienna, Austria; [Veiros, Luis F.] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal in 2019, Cited 56. HPLC of Formula: C14H11N. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

An efficient additive-free manganese-catalyzed hydrogenation of nitriles to primary amines with molecular hydrogen is described. The pre-catalyst, a well-defined bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dpre)(CO)(3)(CH3)] (dpre=1,2-bis(di-n-propylphosphino)ethane), undergoes CO migratory insertion into the manganese-alkyl bond to form acyl complexes which upon hydrogenolysis yields the active coordinatively unsaturated Mn(I) hydride catalyst [Mn(dpre)(CO)(2)(H)]. A range of aromatic and aliphatic nitriles were efficiently and selectively converted into primary amines in good to excellent yields. The hydrogenation of nitriles proceeds at 100 degrees C with a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar. Mechanistic insights are provided by means of DFT calculations.

HPLC of Formula: C14H11N. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Biswal, P; Samser, S; Nayak, P; Chandrasekhar, V; Venkatasubbaiah, K in AMER CHEMICAL SOC published article about ONE-POT SYNTHESIS; CONJUGATE ADDITION; ALPHA-METHYLATION; KETONES; ALCOHOLS; AMINES; SESQUITERPENOIDS; ALKYLATION; REACTIVITY; EFFICIENT in [Biswal, Priyabrata; Samser, Shaikh; Nayak, Prakash; Venkatasubbaiah, Krishnan] Natl Inst Sci Educ & Res NISER, Sch Chem Sci, Bhubaneswar 752050, Odisha, India; [Chandrasekhar, Vadapalli] Tata Inst Fundamental Res Hyderabad, Hyderabad 500046, Telangana, India; [Chandrasekhar, Vadapalli] Indian Inst Technol Kanpur, Dept Chem, Kanpur 208016, Uttar Pradesh, India in 2021.0, Cited 67.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A novel cobalt(II)porphyrin-mediated acceptorless dehydrogenation of methanol is reported for the first time. This methodology has been applied for the coupling of a variety of ketones with methanol to produce 1,5-diketones along with H-2 and H2O as the environment friendly byproducts. This paradigm was also demonstrated for a one-pot synthesis of substituted pyridines using a sequential addition protocol where the 1,5-diketones were generated in situ. From many experiments including those involving deuterium labeling, it is proposed that protonated cobalt(II)-porphyrin methoxide complex acts as an intermediate to generate formaldehyde along with a metal hydride.

Quality Control of 1-(4-Nitrophenyl)ethanone. Welcome to talk about 100-19-6, If you have any questions, you can contact Biswal, P; Samser, S; Nayak, P; Chandrasekhar, V; Venkatasubbaiah, K or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article N,S-Codoped Carbon Shells Embedded with Ultrafine Co NPs for Reductive Amination with Formic Acid WOS:000467351200092 published article about COVALENT ORGANIC FRAMEWORK; N-DOPED CARBON; OXYGEN REDUCTION; TRANSFER HYDROGENATION; NITRO-COMPOUNDS; COBALT NANOPARTICLES; GRAPHENE; METAL; CATALYST; ELECTROCATALYSTS in [Guo, Haotian; Wang, Bowei; Qiu, Pengzhi; Gao, Ruixiao; Sun, Mingming; Chen, Ligong] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China; [Wang, Bowei; Chen, Ligong] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China; [Wang, Bowei; Chen, Ligong] Tianjin Engn Res Ctr Funct Fine Chem, Tianjin, Peoples R China; [Guo, Haotian] Emory Univ, Dept Chem, 1515 Pierce Dr, Atlanta, GA 30322 USA in 2019.0, Cited 67.0. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Herein, N,S-codoped carbon materials embedded with ultrafine and well-distributed Co nanoparticles (1.14 wt % Co) were prepared through pyrolysis of the hybrids of SNW-1 and Co(Ac)(2) coated with glucose. It was observed by TEM and XRD that Co nanoparticles (NPs) were entrapped in doped carbon shells uniformly. The glucose coating presented a significant impact on the size distribution of Co NPs and doped modes of heteroatoms, especially the S species. The catalyst displayed outstanding activity for catalytic transfer hydrogenation (CTH) with formic acid under the base-free system. Encouragingly, diverse secondary amines were produced in excellent yields through the domino reaction of hydrogenation and reductive amination. Remarkably, the catalyst with ultrafine Co NPs showed good durability under harsh reaction conditions and displayed no significant loss in both activity and selectivity in 5 runs. This was attributed to the protection of constructed N,S dual-doped carbon shells. Hence, we offer an alternative strategy for the construction of dual-doped carbon materials trapped with ultrafine transition metal, which can be further applied in various catalytic processes.

Formula: C8H7NO3. Welcome to talk about 100-19-6, If you have any questions, you can contact Guo, HT; Wang, BW; Qiu, PZ; Gao, RX; Sun, MM; Chen, LG or send Email.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 86-29-3. Yuen, OY; Chen, XM; Wu, JY; So, CM in [Yuen, On Ying; Chen, Xiangmeng; Wu, Junyu; So, Chau Ming] Hong Kong Polytech Univ, State Key Lab Chem Biol & Drug Discovery, Hung Hom, Kowloon, Hong Kong, Peoples R China; [Yuen, On Ying; Chen, Xiangmeng; Wu, Junyu; So, Chau Ming] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hung Hom, Kowloon, Hong Kong, Peoples R China; [So, Chau Ming] Hong Kong Polytech Univ, Shenzhen Res Inst, Shenzhen, Peoples R China published Palladium-Catalyzed Direct alpha-Arylation of Arylacetonitriles with Aryl Tosylates and Mesylates in 2020, Cited 49. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

The first general palladium-catalyzed alpha-arylation of arylacetonitriles with aryl and heteroaryl sulfonates are reported. Pd(OAc)(2) associated with XPhos serves as the effective catalyst to facilitate this reaction. A broad range of electron-rich, -neutral, -deficient, and sterically hindered aryl/heteroaryl tosylates and mesylates are coupled with arylacetonitriles bearing different substituents to give the corresponding products in good to excellent yields. Catalyst loading down to 0.1 mol-% Pd was achieved, and 22 unprecedented compounds were synthesized from 43 demonstrated examples using this method. Its applicability with the modification of biological phenolic compounds was successfully demonstrated. The Pd/XPhos system catalyzed the alpha-arylation and followed by alkylation in one-pot sequential conditions, resulting in the direct synthesis of compounds containing quaternary center- and deuterium-containing compounds in good to excellent yields.

Recommanded Product: 86-29-3. Bye, fridends, I hope you can learn more about C14H11N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. In 2021.0 NEW J CHEM published article about POLY(ETHYLENE GLYCOL); CYCLOADDITION; DERIVATIVES; LIBRARY; 3-AMINO-2-OXINDOLES; SPIROINDOLONES; CONSTRUCTION; ANTAGONIST; SCAFFOLDS; RECEPTOR in [Yue, Guizhou; Jiang, Dan; Dou, Zhengjie; Li, Sicheng; Feng, Juhua; Zhang, Li; Wang, Xianxiang] Sichuan Agr Univ, Coll Sci, Yaan 625014, Sichuan, Peoples R China; [Chen, Huabao; Yang, Chunping] Sichuan Agr Univ, Coll Agron, Chengdu 611130, Sichuan, Peoples R China; [Yin, Zhongqiong; Song, Xu; Liang, Xiaoxia] Sichuan Agr Univ, Coll Vet Med, Chengdu 611130, Sichuan, Peoples R China; [Lu, Cuifen] Hubei Univ, Hubei Collaborat Innovat Ctr Adv Organochem Mat, Wuhan 430062, Peoples R China; [Lu, Cuifen] Hubei Univ, Key Lab Synth & Applicat Organ Funct Mol, Minist Educ, Wuhan 430062, Peoples R China in 2021.0, Cited 62.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

The umpolung Michael addition of isatin N,N’-cyclic azomethine imine 1,3-dipoles with chalcones is reported. The reaction could be finished within a very short time (0.3-2 min), with 3,3-disubstituted oxindole derivatives obtained in moderate to excellent yields with promising dr values. Unusual Michael adducts were obtained in moderate to high yields (26-98%) with low to high diastereoselectivities (0.8 : 1 to 8.5 : 1 dr). All the synthesized compounds (3, 3′, 4, 5, 5′, 7, 7′, 9 and 9′) were well characterized by FTIR, NMR, and mass spectral analyses and further confirmed by the single-crystal X-ray diffraction analysis of compounds 3aa and 4n.

Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis and applications of carbohydrate based chiral ionic liquids as chiral recognition agents and organocatalysts WOS:000512219300036 published article about SODIUM-BOROHYDRIDE REDUCTIONS; CAPILLARY-ELECTROPHORESIS; ENANTIOSEPARATION in [Kaur, Nirmaljeet; Chopra, Harish Kumar] St Longowal Inst Engn & Technol, Dept Chem, Longowal 148106, India in 2020.0, Cited 38.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Chiral ionic liquids (CILs) have shown a wide range of applications in variety of domains in chemistry. Because of this, synthesis and applications of CILs have always been areas of interest for research in the last 20 years. Present work describes, the synthesis of six carbohydrate based chiral ionic liquids (CCILs) by following simple procedures and their applications. Structures of the cats were confirmed through various analytical techniques like NMR spectroscopy (H-1, C-13, B-11, P-31,F-19), El-MS, and polarimetry. Designed CCILs were tested as chiral recognising agents using sodium salt of Mosher’s acid as model substrate through (FNMR)-F-19-N- spectroscopy. Further, Cats were used as organocatalyst in the enantioselective reduction of aromatic prochiral ketones to achieve corresponding chiral secondary alcohols. (C) 2019 Elsevier B.V. All rights reserved.

Welcome to talk about 100-19-6, If you have any questions, you can contact Kaur, N; Chopra, HK or send Email.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 86-29-3. Authors Babon, JC; Esteruelas, MA; Fernandez, I; Lopez, AM; Onate, E in AMER CHEMICAL SOC published article about in [Babon, Juan C.; Esteruelas, Miguel A.; Lopez, Ana M.; Onate, Enrique] Univ Zaragoza, Ctr Innovac Quim Avanzada ORFEO CINQA, Inst Sintesis Quim & Catalisis Homogenea ISQCH, Dept Quim Inorgan,CSIC, Zaragoza 50009, Spain; [Fernandez, Israel] Univ Complutense Madrid, Ctr Innovac Quim Avanzada ORFEO CINQA, Fac Ciencias Quim, Dept Quim Organ 1, Madrid 28040, Spain in 2020, Cited 69. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

Complex OsH6((PPr3)-Pr-i)(2) is an efficient catalyst precursor for the addition of pinacolborane and catecholborane to the C-N triple bond of alkyl nitrites. In this way, a variety of N,N-diborylamines have been isolated and fully characterized, including 13 derivatives not described so far. The range of nitrites used is wide and comprises substrates having unfunctionalized linear and branched chains, and functionalized chains with methoxide, trifluoromethyl, aryl, pyridyl, benzoyl, or cyanide groups. Kinetic studies demonstrate that the overall process consists of two consecutive irreversible reactions: the catalytic metal-promoted monohydroboration of the nitrile to afford the borylimine and the metal-free stoichiometric hydroboration of the latter to give the diborylamine. The mechanism of the hydroboration has been established by combining the kinetic analysis of the catalysis, stoichiometric reactions, and DFT calculations. The rate-determining step of the catalysis is the insertion of the C-N triple bond of the nitrite into the Os-B bond of an osmium-sigma-borane intermediate and is regiodirected by the nucleophilicity of the nitrogen atom and the electrophilicity of the carbon atom of the nitrite.

Welcome to talk about 86-29-3, If you have any questions, you can contact Babon, JC; Esteruelas, MA; Fernandez, I; Lopez, AM; Onate, E or send Email.. Product Details of 86-29-3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Liu, JZ; Qiu, X; Huang, XQ; Luo, X; Zhang, C; Wei, JL; Pan, J; Liang, YJ; Zhu, YC; Qin, QX; Song, S; Jiao, N in NATURE PUBLISHING GROUP published article about C-C BOND; H AMINATION; CLEAVAGE; ACTIVATION; CATALYSIS; NITROGENATION; NITRATION; HYDROGEN; AMINES in [Liu, Jianzhong; Qiu, Xu; Huang, Xiaoqiang; Luo, Xiao; Zhang, Cheng; Wei, Jialiang; Pan, Jun; Liang, Yujie; Zhu, Yuchao; Qin, Qixue; Song, Song; Jiao, Ning] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing, Peoples R China; [Jiao, Ning] Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai, Peoples R China in 2019.0, Cited 50.0. Category: benzodioxans. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Anilines are fundamental motifs in various chemical contexts, and are widely used in the industrial production of fine chemicals, polymers, agrochemicals and pharmaceuticals. A recent development for the synthesis of anilines uses the primary amination of C-H bonds in electron-rich arenes. However, there are limitations to this strategy: the amination of electron-deficient arenes remains a challenging task and the amination of electron-rich arenes has a limited control over regioselectivity-the formation of meta-aminated products is especially difficult. Here we report a site-directed C-C bond primary amination of simple and readily available alkylarenes or benzyl alcohols for the direct and efficient preparation of anilines. This chemistry involves a novel C-C bond transformation and offers a versatile protocol for the synthesis of substituted anilines. The use of O-2 as an environmentally benign oxidant is demonstrated, and studies on model compounds suggest that this method may also be used for the depolymerization of lignin.

Welcome to talk about 100-19-6, If you have any questions, you can contact Liu, JZ; Qiu, X; Huang, XQ; Luo, X; Zhang, C; Wei, JL; Pan, J; Liang, YJ; Zhu, YC; Qin, QX; Song, S; Jiao, N or send Email.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Name: 1-(4-Nitrophenyl)ethanone. In 2019.0 CATAL COMMUN published article about GOLD NANOPARTICLES; REDUCTION; OXIDE; NITRO; 4-NITROPHENOL in [Ray, Shounak; Biswas, Papu] Indian Inst Engn Sci & Technol, Dept Chem, Coll Rd, Howrah 711103, India in 2019.0, Cited 29.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

3,6-Di(pyridin-2-yl)-1,2,4,5-s-tetrazine capped-silver nanoparticles (TzAgNPs) exhibit an excellent catalytic activity and chemoselectivity for the reduction of various substituted nitroarenes to the corresponding aromatic amines in aqueous medium with sodium borohydride and hydrazine hydrate as a hydrogen donor at room temperature. The reaction kinetics of the reduction of 4-nitrophenol to 4-aminophenol has also been studied to determine the apparent rate constant. The catalyst TzAgNPs efficiently reduces the nitro group under very mild conditions, thus affording excellent yields within very short reaction time (<20 min), and shows high selectivity even in the presence of other sensitive functional groups. Name: 1-(4-Nitrophenyl)ethanone. Bye, fridends, I hope you can learn more about C8H7NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem