An article Synthesis and biological activity of new chalcone scaffolds as prospective antimicrobial agents WOS:000607036700005 published article about STAPHYLOCOCCUS-AUREUS MRSA; METHICILLIN-RESISTANT; ANALOGS in [Narwal, Sangeeta] Indira Gandhi Univ, Dept Pharmaceut Sci, Rewari 123401, Haryana, India; [Kumar, Sanjiv] Chaudhary Bansi Lal Univ, Dept Pharmaceut Sci, Bhiwani 127021, Haryana, India; [Verma, Prabhakar Kumar] Maharshi Dayanand Univ, Dept Pharmaceut Sci, Rohtak 124001, Haryana, India in 2021, Cited 36. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone
Chalcones are open-chain flavonoids which contains two aromatic rings are joined by 3-carbons alpha-, beta-unsaturated carbonyl chain. The, beta-unsaturated ketonic group which is liable for the antimicrobial activity of the chalcone is additionally of vast use in further chemical modification into a variety of heterocyclic compounds. A new series of chalcone derivatives was synthesized and characterized by spectral analysis (IR, 1H-NMR, 13C-NMR, MS and elemental analysis) and evaluated for its in vitro antimicrobial activity against bacterial (Gram negative and Gram positive) and fungal strains using tube dilution method. The antimicrobial screening results revealed that some compounds of the series 1 (MICpa = 1.16 mu M), 3 (MICbs = 1.82 mu M), 6 (MICan = 2.09 mu M), 8 (MICec and se = 0.94 and 1.88 mu M) and 17 (MICsa and ca = 0.91 and 1.81 mu M) showed the most promising antimicrobial activity against both Gram-positive as well as Gram-negative bacterial and fungal strains, and comparable to the standard drugs used as positive control (cefadroxil and fluconazole).
Name: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Narwal, S; Kumar, S; Verma, PK or concate me.
Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem