Month: November 2021

Product Details of 86-29-3. In 2020 CHEM COMMUN published article about PALLADIUM-CATALYZED CYANATION; HIGHLY EFFICIENT; BECKMANN REARRANGEMENT; PRIMARY AMIDES; DEHYDRATION; ARYL; ISOCYANIDES in [Zhang, Wei; Lin, Jin-Hong; Xiao, Ji-Chang] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Zhang, Pengfei] Cent South Univ, Xiangya Hosp, Dept Oncol, NHC Key Lab Canc Prote, 87 Xiangya Rd, Changsha 410008, Hunan, Peoples R China in 2020, Cited 57. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

For the dehydroxylation of aldoximes with 4-nitro-1-((trifluoromethyl)sulfonyl)-imidazole (NTSI), slight modifications of reaction conditions resulted in significantly different reaction paths to provide either nitriles or isonitriles. The challenging conversion of aldoximes into isonitriles was achieved under mild conditions.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Zhang, W; Lin, JH; Zhang, PF; Xiao, JC or concate me.. Product Details of 86-29-3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Old Concepts, New Application – Additive-Free Hydrogenation of Nitriles Catalyzed by an Air Stable Alkyl Mn(I) Complex WOS:000492768500001 published article about MOLECULAR-ORBITAL METHODS; GAUSSIAN-TYPE BASIS; PRIMARY AMINES; SELECTIVE HYDROGENATION; EQUILIBRIUM GEOMETRIES; INSERTION REACTIONS; HYDROFORMYLATION; HYDROGENOLYSIS; APPROXIMATION; ALDEHYDES in [Weber, Stefan; Kirchner, Karl] Vienna Univ Technol, Inst Appl Synthet Chem, Getreidemarkt 9-163-AC, A-1060 Vienna, Austria; [Veiros, Luis F.] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal in 2019, Cited 56. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Recommanded Product: 2,2-Diphenylacetonitrile

An efficient additive-free manganese-catalyzed hydrogenation of nitriles to primary amines with molecular hydrogen is described. The pre-catalyst, a well-defined bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dpre)(CO)(3)(CH3)] (dpre=1,2-bis(di-n-propylphosphino)ethane), undergoes CO migratory insertion into the manganese-alkyl bond to form acyl complexes which upon hydrogenolysis yields the active coordinatively unsaturated Mn(I) hydride catalyst [Mn(dpre)(CO)(2)(H)]. A range of aromatic and aliphatic nitriles were efficiently and selectively converted into primary amines in good to excellent yields. The hydrogenation of nitriles proceeds at 100 degrees C with a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar. Mechanistic insights are provided by means of DFT calculations.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Weber, S; Veiros, LF; Kirchner, K or concate me.. Recommanded Product: 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Copper-Catalyzed Carbonylative Synthesis of beta-Homoprolines from N-Fluoro-sulfonamides WOS:000518875500038 published article about ASYMMETRIC-SYNTHESIS; ANALOGS; AMINES; TRANSFORMATION; HETEROCYCLES; PEPTIDES; ACIDS in [Zhang, Youcan; Yin, Zhiping; Wu, Xiao-Feng] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany in 2020, Cited 45. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Category: benzodioxans

A new methodology for the carbonylative transformation of N-fluoro-sulfonamides into N-sulfonyl-beta-homoproline esters has been described. In the presence of a catalytic amount of Cu(OTf)(2), a range of beta-homoproline derivatives were prepared in moderate to good yield. The reaction proceeds via the intramolecular cyclization and intermolecular carbonylation of a free carbon radical. Notably, this procedure offers the possibility to build potential functionalized bioactive molecules.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Zhang, YC; Yin, ZP; Wu, XF or concate me.. Category: benzodioxans

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. Zhang, GJ; Tang, FY; Wang, XY; An, P; Wang, LQ; Liu, YN in [Zhang, Guangji; Tang, Feiying; An, Ping; Wang, Liqiang; Liu, You-Nian] Cent South Univ, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China; [Zhang, Guangji; Wang, Liqiang; Liu, You-Nian] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China; [Wang, Xiaoying] Qilu Univ Technol, State Key Lab Biobased Mat & Green Papermaking, Jinan 250353, Shandong, Peoples R China published Co,N-Codoped Porous Carbon-Supported CoyZnS with Superior Activity for Nitroarene Hydrogenation in 2020.0, Cited 55.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

It is a persistent target to develop noble-metal-free catalysts that can achieve chemoselective hydrogenation of nitro compounds under mild reaction conditions. In this work, we report a new strategy for preparation of hydrogenation catalysts containing both CoNx and CoyZnS supported on N-doped porous carbon (CoNx-CoyZnS@NPC-Z). The CoNx-CoyZnS@NPC-Z catalysts were prepared by pyrolyzing the protein-metal-ion networks, followed by treatment with acid. We found that CoNxCoyZnS@NPC-3 catalyst delivers high catalytic activity and selectivity, affording almost full conversion and >98% selectivity in water/methanol mixture solvents at 90 degrees C under 5 bar of H-2 pressure for 3 h of reaction. Notably, the catalytic hydrogenation can work even under 1 bar of H-2 pressure and at room temperature with high conversion and selectivity. Besides, CoNx-CoyZnS@NPC-3 exhibits remarkable tolerance to CO or H2S poisoning and acid erosion.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, GJ; Tang, FY; Wang, XY; An, P; Wang, LQ; Liu, YN or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Safety of 1-(4-Nitrophenyl)ethanone. Recently I am researching about ELECTROLUMINESCENCE PROPERTIES; ENERGY-TRANSFER; SINGLE-POLYMER; QUANTUM DOTS; SOLID-STATE; EMISSION; BLUE; EFFICIENT; DIODES; FLUORESCENCE, Saw an article supported by the Department of Atomic Energy (DAE-SRC) India [21/13/2015BRNS/35029]; CSIRCouncil of Scientific & Industrial Research (CSIR) – India; UGC, New DelhiUniversity Grants Commission, India. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sharma, CP; Gupta, NM; Singh, J; Yadav, RAK; Dubey, DK; Rawat, KS; Jha, AK; Jou, JH; Goel, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A series of donor-acceptor pyranones (3a-m, 4a-h) were synthesized using alpha-oxo-ketene-S,S-acetal as the synthon for their application as emissive materials for energy-saving organic light-emitting devices (OLEDs). Among them, five pyranones 3f, 3g, 3h, 3m, and 4e exhibited highly bright fluorescence in the solid state and weak or no emission in the solution state. Photophysical analysis of these dyes revealed that only 3f and 3m showed aggregation-induced emission behavior in a THF/water mixture (0-99%) with varying water fractions (f(w)) leading to bright fluorescence covering the entire visible region, while other derivatives 3g, 3h, and 4e did not show any fluorescence signal. The computational studies of the compounds revealed that the longer wavelength absorption originates from HOMO to LUMO electronic excitation. These dyes exhibited good thermal stability with 5% weight loss temperature in the range of 218-347 degrees C. The potential application of the donor-acceptor pyranone dyads was demonstrated by fabrication of solution-processed OLEDs. Remarkably, OLED devices prepared using highly emissive compounds 6-(anthracen-9-yl)-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile (3m) and 6-(4-methoxyphenyl)-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile (3f) displayed pure white emission with CIE coordinates of (0.29, 0.31) and (0.32, 0.32), respectively. Additionally, the resultant devices exhibited external quantum efficiencies of 1.9 and 1.2% at 100 cd m(-2), respectively.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sharma, CP; Gupta, NM; Singh, J; Yadav, RAK; Dubey, DK; Rawat, KS; Jha, AK; Jou, JH; Goel, A or concate me.. Safety of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 100-19-6. I found the field of Chemistry very interesting. Saw the article Stereoselective Reducing Complexes Supported in Solid Phase: Preparation and Reactivity Study published in 2019.0, Reprint Addresses Galvez-Ruiz, JC (corresponding author), Univ Sonora, Dept Ciencias Quim Biol, Hermosillo 83000, Sonora, Mexico.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

Twelve new chiral chelating resins have been prepared using solid phase organic synthesis with the Merrifield and Wang resins and the bidentate amine 1,2-ethylenediamine, followed by the coupling of asymmetric ketones such as 1-phenyletanone, 4-methyl-2-pentanone 4-nitroacetophenone and 4-methoxyacetophenone to form prochiral imines. The enantioselective reduction with borane and (R)-(+)-2-Methyl-CBS-oxazaborolidine leads to the chiral resins with yields greater than 86%. We used these chiral resins to prepare 24 reducing complexes with alkali tetrahydroborates in a very simple way giving yields greater than 87%. Finally, we achieved a preliminary enantioselective reduction of acetophenone employing the Merrifield’s chiral chelating resins obtaining the corresponding S alcohol in a 70:30 ratio with the R analog alcohol.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Vargas-Durazo, J; Aguilar-Martinez, M; Ochoa-Teran, A; Santacruz-Ortega, H; Alonzo, FR; Meza, NG; Galvez-Ruiz, JC or concate me.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Study of the effect of the ligand structure on the catalytic activity of Pd@ ligand decorated halloysite: Combination of experimental and computational studies WOS:000465346500020 published article about HETEROGENEOUS CATALYST; PALLADIUM NANOPARTICLES; BOND ORDER; NITROBENZENE HYDROGENATION; FUNCTIONALIZED HALLOYSITE; SELECTIVE HYDROGENATION; GREEN SYNTHESIS; BASIS-SETS; NANOTUBES; PSEUDOPOTENTIALS in [Dehghani, Sevda; Bahri-Laleh, Naeimeh; Nekoomanesh-Haghighi, Mehdi] Iran Polymer & Petrochem Inst, Polymerizat Engn Dept, POB 14965-115, Tehran, Iran; [Sadjadi, Samahe] Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, POB 14975-112, Tehran, Iran; [Poater, Albert] Univ Girona, Inst Quim Computac & Catalisi, C Maria Aurelia Capmany 69, Girona 17003, Catalonia, Spain; [Poater, Albert] Univ Girona, Dept Quim, C Maria Aurelia Capmany 69, Girona 17003, Catalonia, Spain in 2019.0, Cited 57.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Formula: C8H7NO3

Taking advantage of computational chemistry, the best diamine for the synthesis of a multi-dentate ligand from the reaction with 3-(trimethoxysilyl) propylisocyanate (TEPI) was selected. Actually, predictive Density Functional Theory (DFT) calculations provided the right diamino chain, i.e. ethylenediamine, capable to sequester a palladium atom, together with the relatively polar solvent toluene, and then undergo the experiments as a selective catalytic agent. The ligand was then prepared and applied for the decoration of the halloysite (Hal) outer surface to furnish an efficient support for the immobilization of Pd nanoparticles. The resulting catalyst exhibited high catalytic activity for hydrogenation of nitroarenes. Moreover, it showed high selectivity towards nitro functional group. The study of the catalyst recyclability confirmed that the catalyst could be recycled for several reaction runs with only slight loss of the catalytic activity and Pd leaching. Hot filtration test also proved the heterogeneous nature of the catalysis.

Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Dehghani, S; Sadjadi, S; Bahri-Laleh, N; Nekoomanesh-Haghighi, M; Poater, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles by Continuous Flow: Application to the Synthesis of Valsartan WOS:000535293600015 published article about CATALYZED SYNTHESIS; HYDRAZOIC ACID; CHEMISTRY; TETRAZOLES; REAGENTS; SAFE; CYCLOADDITION; SALTS in [Carpentier, Florian; Felpin, Francois-Xavier; Zammattio, Francoise; Le Grognec, Erwan] Univ Nantes, CNRS, CEISAM, UMR 6230, F-44000 Nantes, France in 2020, Cited 46. Recommanded Product: 86-29-3. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

An efficient continuous flow process for the synthesis of 5-substituted 1H-tetrazoles is described. The process involves the reaction between a polymer-supported triorganotin azide and organic nitriles. The polymer-supported organotin azide, which is in situ generated with a polystyrene-supported triorganotin alkoxide and trimethylsilylazide, is immobilized in a packed bed reactor. This approach is simple, fast (it takes from 7.5 to 15 min), and guarantees a low concentration of tin residues in the products (<5 ppm). The process was developed to aryl-, heteroaryl-, and also alkylnitriles and was applied for the synthesis of valsartan, an angiotensin II receptor antagonist. Recommanded Product: 86-29-3. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Carpentier, F; Felpin, FX; Zammattio, F; Le Grognec, E or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Molecular Hybrids Integrated with Benzimidazole and Pyrazole Structural Motifs: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies WOS:000530659700050 published article about 2 CHK2 INHIBITORS; POTENTIAL ANTICANCER; CARBAZOLES SYNTHESIS; DERIVATIVES; DISCOVERY; SCAFFOLD; BENDAMUSTINE; MOIETY; DRUGS in [Sivaramakarthikeyan, Ramar; Shunmugam, Iniyaval; Vadivel, Saravanan; Ramalingan, Chennan] Kalasalingam Acad Res & Educ Deemed Be Univ, Sch Adv Sci, Dept Chem, Krishnankoil 626126, Tamil Nadu, India; [Lim, Wei Meng; Mai, Chun-Wai] Int Med Univ, Sch Pharm, Kuala Lumpur 57000, Malaysia; [Mai, Chun-Wai] Int Med Univ, Ctr Canc & Stem Cell Res, Inst Res Dev & Innovat IRDI, Kuala Lumpur 57000, Malaysia in 2020.0, Cited 67.0. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a-6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a hybridpossessing para-nitrophenyl moiety connected to a pyrazole scaffold (6a) exerted the highest anti-inflammatory activity, which is superior to the standard, diclofenac sodium. While executing the 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, a hybrid-possessing para-bromophenyl unit integrated at the pyrazole structural motif (6i) exhibited the highest activity among the hybrids examined. Besides, evaluation of anticancer potency of the synthesized hybrids revealed that the one containing a para-fluorophenyl unit tethered at the pyrazole nucleus (6h) showed the highest activity against both the pancreatic cancer cells (SW1990 and AsPCl) investigated. Considerable binding affinity between B-cell lymphoma and the hybrid, 6h has been reflected while performing molecular docking studies (-8.65 kcal/mol). The outcomes of the investigation expose that these hybrids could be used as effective intermediates to construct more potent biological agents.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sivaramakarthikeyan, R; Shunmugam, I; Vadivel, S; Lim, WM; Mai, CW; Ramalingan, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Dale, HJA; Nottingham, C; Poree, C; Lloyd-Jones, GC in AMER CHEMICAL SOC published article about in [Dale, Harvey J. A.; Nottingham, Chris; Poree, Carl; Lloyd-Jones, Guy C.] Univ Edinburgh, Sch Chem, Edinburgh EH9 3FJ, Midlothian, Scotland in 2021.0, Cited 50.0. SDS of cas: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Alkylidene carbenes undergo rapid inter- and intramolecular reactions and rearrangements, including 1,2-migrations of beta-substituents to generate alkynes. Their propensity for substituent migration exerts profound influence over the broader utility of allcylidene carbene intermediates, yet prior efforts to categorize 1,2-migratory aptitude in these elusive species have been hampered by disparate modes of carbene generation, ultrashort carbene lifetimes, mechanistic ambiguities, and the need to individually prepare a series of C-13-labeled precursors. Herein we report on the rearrangement of C-13-alkylidene carbenes generated in situ by the homologation of carbonyl compounds with [C-13]-Li-TMS-diazomethane, an approach that obviates the need for isotopically labeled substrates and has expedited a systematic investigation (C-13{H-1} NMR, DLPNO-CCSD(T)) of migratory aptitudes in an unprecedented range of more than 30 alkylidene carbenes. Hammett analyses of the reactions of 26 differentially substituted benzophenones reveal several counterintuitive features of 1,2-migration in alkylidene carbenes that may prove of utility in the study and synthetic application of unsaturated carbenes more generally.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Dale, HJA; Nottingham, C; Poree, C; Lloyd-Jones, GC or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem