Day: November 1, 2021

An article Frustrated Lewis pairs: A real alternative to deuteride/tritide reductions WOS:000492827500007 published article about HETEROLYTIC DIHYDROGEN ACTIVATION; METAL-FREE HYDROGENATION; H/D-EXCHANGE; LABELED COMPOUNDS; HEAVY ISOTOPES; TRITIUM; DISCOVERY; DRUG; FUNCTIONALIZATION; DEUTERATION in [Doubkova, Sabina; Marek, Ales] Czech Acad Sci, Inst Organ Chem & Biochem, Flemingovo 542-2, Prague 16610 6, Czech Republic in 2019.0, Cited 60.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

Deuterium- and tritium-labeled compounds play a principal role in tracing of biologically active molecules in complicated biochemical systems. The state-of-the-art techniques using noble metal catalysts or strong reducing agents often suffers from low functional group tolerances, poor selectivity, tricky or multistep synthesis of reagents, and low specific activity of the labeled product. Herein, we demonstrate a mild and nonmetallic technique of deuteration and tritiation of polarized double bonds, such as carbonyl compounds, yielding labeled alcohols of high specific activities. This one-pot synthesis uses carrier-free hydrogen gas in situ activated by a freshly prepared frustrated Lewis pair, generating reducing reagents. This labeling strategy shows better selectivity and functional group tolerances compared with current reductive methods. Reported is an example of the selective reduction of the aldehyde moiety of 3-acetylbenzaldehyde. What makes this technology groundbreaking is its mildness, selectivity, and generation of limited amount of radioactive waste as almost no byproducts were generated after use of (B(C6F5)(3)H-3)((HTMP)-H-3) reducing reagent. Radiochemical purity of desired H-3-labeled product in a crude reaction mixture was determined of over 94%. This work provides, to the community of radiochemists, a practical protocol for frustrated Lewis pairs (FLP)-assisted deuterium/tritium labeling technology.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Doubkova, S; Marek, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Ammonium chloride-catalyzed green multicomponent synthesis of dihydropyrazine and tetrahydrodiazepine derivatives on water WOS:000478882900005 published article about ONE-POT SYNTHESIS; 3,4-DIHYDROQUINOXALIN-2-AMINE DERIVATIVES; 3-COMPONENT SYNTHESIS; EFFICIENT; 4-COMPONENT; PYRAZINE; ISOCYANIDES; CHEMISTRY in [Shaabani, Ahmad; Sepahvand, Heshmatollah; Ghasemi, Shima] Shahid Beheshti Univ, Dept Chem, POB 19396-4716, Tehran, Iran in 2019.0, Cited 51.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Category: benzodioxans

This research describes a simple and efficient one-pot synthetic approach for the preparation of tetrahydrodiazepine and dihydropyrazine (or dihydroquinoxaline) derivatives in high yields in the presence of a substoichiometric amount of ammonium chloride as a green accelerator on water at 50 degrees C within 1-3 h. [GRAPHICS] .

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shaabani, A; Sepahvand, H; Ghasemi, S or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Palladium-Catalyzed C-H Arylation of Aliphatic and Aromatic Ketones using Dipeptide Transient Directing Groups WOS:000466161500014 published article about CARBON-CARBON BONDS; C(SP(3))-H FUNCTIONALIZATION; ALDEHYDES; OSTEOARTHRITIS; NABUMETONE; ACTIVATION; MANAGEMENT; AMIDATION; SAFETY; DRUG in [Cheng, Yaohang; Zheng, Jie; Tian, Chao; He, Yuhang; Zhang, Cong; Tan, Qi; An, Guanghui; Li, Guangming] Heilongjiang Univ, Key Lab Funct Inorgan Mat Chem MOE, Sch Chem & Mat Sci, 74 Xuefu Rd, Harbin 150080, Heilongjiang, Peoples R China; [An, Guanghui] Harbin Engn Univ, Coll Mat Sci & Chem Engn, Harbin 150001, Heilongjiang, Peoples R China in 2019.0, Cited 52.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Ketones are ubiquitous structural motifs in chemical materials and medicinally active pharmaceutical ingredients. Transition metal-catalyzed C-H bond functionalization is one of the most efficient tactics for diversification of ketones. Palladium-catalyzed C-H arylation of aliphatic and aromatic ketones has been achieved utilizing an inexpensive dipeptide as a transient directing group. The tridentate coordination used in this reaction enhances the reactivity of the substrates and allows reduction of the loading of the directing group compounds to 20%. This approach allows rapid arylation of complex natural products, medicinal-chemistry-related scaffolds, and even remote C(sp(2))-H bonds.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Cheng, YH; Zheng, J; Tian, C; He, YH; Zhang, C; Tan, Q; An, GH; Li, GM or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Williams, UJ in AMER CHEMICAL SOC published article about in [Williams, Ursula J.] Juniata Coll, Dept Chem & Biochem, Huntingdon, PA 16652 USA in 2020.0, Cited 13.0. HPLC of Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The Organisation for the Prohibition of Chemical Weapons (OPCW) has identified education and outreach as vital to global efforts that emphasize the responsible use of chemicals. To promote students’ exposure to broad-reaching applications of analytical chemistry, a chemical-weapons-themed project was implemented in an upper-level analytical chemistry course. In this project, students developed laboratory and data analysis skills needed to complete organic structure analysis, professionally communicated their data and conclusions, and considered chemical analysis in an applied context. This project grounds the topic of multiuse chemicals in a case-based, active-learning context.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Williams, UJ or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Quality Control of 1-(4-Nitrophenyl)ethanone. Chen, LW; Wu, ZY; Nan, H; Wang, L; Chu, SQ; Liang, HW in [Chen, Lin-Wei; Wu, Zhen-Yu; Nan, Hang; Wang, Lei; Liang, Hai-Wei] Univ Sci & Technol China, Dept Chem, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China; [Chu, Sheng-Qi] Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China published A metal-catalyzed thermal polymerization strategy toward atomically dispersed catalysts in 2019, Cited 31. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

We report a general metal-catalyzed thermal polymerization strategy for the preparation of atomically dispersed catalysts that consist of isolated metal atoms (Fe, Co and Ni) hosted by a polymer-like carrier containing phenanthroline substructure. The prepared atomically dispersed cobalt catalysts exhibit high selectivity, activity, and reusability in catalyzing aromatic alkane oxidation.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chen, LW; Wu, ZY; Nan, H; Wang, L; Chu, SQ; Liang, HW or concate me.. Quality Control of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Baydas, Y; Dertli, E; Sahin, E in [Baydas, Yasemin; Dertli, Enes] Bayburt Univ, Fac Engn, Dept Food Engn, Bayburt, Turkey; [Sahin, Engin] Bayburt Univ, Fac Hlth Sci, Dept Nutr & Dietet, TR-6900 Bayburt, Turkey published Green synthesis of chiral aromatic alcohols with Lactobacillus kefiri P2 as a novel biocatalyst in 2020.0, Cited 31.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Biocatalytic reduction is a very important field of research in synthetic organic chemistry. Herein, three different Lactic Acid Bacteria (LAB) strains were evaluated for their bioreduction potential using acetophenone as a model substrate. Among these strains, Lactobacillus kefiri P2 strain was determined as the best asymmetric reduction biocatalyst. Reaction optimization parameters such as reaction time, temperature, agitation speed and pH were systematically optimized using Lactobacillus kefiri P2 strain and model substrate acetophenone. Under these optimized reaction conditions, secondary chiral alcohols were obtained by bioreduction of various prochiral ketones with results up to 99% enantiomeric excess. In addition, the steric and electronic effects of substituents on enantioselectivity and conversion were evaluated. It has been shown that Lactobacillus kefiri P2 biocatalyst was an effective catalyst for asymmetric reduction. This method provides an environmentally friendly method for the synthesis of optically pure alcohols and an alternative approach to chemical catalysts.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Baydas, Y; Dertli, E; Sahin, E or concate me.. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Common Occurrence of Twisted Molecular Crystal Morphologies from the Melt WOS:000569269800058 published article about SPHERULITES; CRYSTALLIZATION; ORIGIN; PREDICTION; POLYMER in [Shtukenberg, Alexander G.; Zhu, Xiaolong; Yang, Yongfan; Kahr, Bart] NYU, Dept Chem, New York, NY 10003 USA; [Shtukenberg, Alexander G.; Zhu, Xiaolong; Yang, Yongfan; Kahr, Bart] NYU, Mol Design Inst, New York, NY 10003 USA in 2020, Cited 49. SDS of cas: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

Two books that describe the forms of thin films of many molecular crystals grown from the melt in polarized light, Gedrillte Kristalle (1929) by Ferdinand Bernauer and Thermomicroscopy in the Analysis of Pharmaceuticals (1971) by Maria Kuhnert-Brandstatter, are analyzed. Their descriptions, especially of curious morphologies consistent with helicoidal twisting of crystalline fibrils or narrow lamellae, are compared in the aggregate with observations from our laboratory collected during the past 10 years. According to Bernauer, 27% of molecular crystals from the melt adopt helicoidal crystal forms under some growth conditions even though helicoids are not compatible with long-range translational symmetry, a feature that is commonly thought to be an a priori condition for crystallinity. Bernauer’s figure of 27% is often met with surprise if not outright skepticism. Kuhnert-Brandstatter was aware of the tell-tale polarimetric signature of twisting (rhythmic interference colors) but observed this characteristic morphology in less than 0.5% of the crystals described. Here, the experience of the authors with 101 arbitrarily selected compounds-many of which are polymorphous-representing 155 total crystal structures, shows an even higher percentage (ca. 31%) of twisted crystals than the value reported by Bernauer. These observations, both positive (twisting) and negative (no twisting), are tabulated. It is concluded that twisting is not associated with molecular structure or crystal structure/symmetry. Rather, these nonclassical morphologies are associated with certain habits with exaggerated aspect ratios, and their appearance is strongly controlled by the growth conditions. Comments are offered in an attempt to reconcile the observations here, and those of Bernauer, the work of seekers of twisted crystals, with those of Kuhnert-Brandstatter, whose foremost consideration was the characterization of polymorphs of compounds of medicinal interest.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shtukenberg, AG; Zhu, XL; Yang, YF; Kahr, B or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis of a rhodium(III) triphenylphosphine complex via C-S bond cleavage of an azo-thioether ligand: X-ray structure, electrochemistry and catalysis towards transfer hydrogenation of ketones WOS:000458228500024 published article about ASYMMETRIC TRANSFER HYDROGENATION; SCHIFF-BASE LIGAND; EFFECTIVE CORE POTENTIALS; DENSITY-FUNCTIONAL THEORY; MOLECULAR CALCULATIONS; EXCITATION-ENERGIES; CARBON-SULFUR; RUTHENIUM(II); ACTIVATION; SULFINATO in [Roy, Puspendu; Manna, Chandan Kumar; Naskar, Rahul; Mondal, Tapan Kumar] Jadavpur Univ, Dept Chem, Kolkata 700032, India; [Roy, Puspendu] Univ Calcutta, Dept Chem, Netaji Nagar Day Coll, Kolkata 700092, India in 2019.0, Cited 49.0. SDS of cas: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A new rhodium(III) triphenylphosphine complex having the general formula [Rh(PPh3)(2)(L)Cl] (1) was synthesized by C-S bond cleavage of an ONS donor azo-thioether ligand (L-CH2Ph). The complex was thoroughly characterized by various spectroscopic techniques. Its single crystal X-ray structure exhibits an octahedral geometry around the rhodium(III) center. A cyclic voltammogram of the complex exhibits ligand based quasi-irreversible oxidative and reductive responses. The electronic structure, redox properties and electronic excitations in the complex were interpreted by DFT and TDDFT calculations. The complex effectively catalyzed the transfer hydrogenation reaction of ketones with high yields in i-PrOH in the presence of a base. (C) 2018 Elsevier Ltd. All rights reserved.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Roy, P; Manna, CK; Naskar, R; Mondal, TK or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 86-29-3. In 2020 CHEM COMMUN published article about PALLADIUM-CATALYZED CYANATION; HIGHLY EFFICIENT; BECKMANN REARRANGEMENT; PRIMARY AMIDES; DEHYDRATION; ARYL; ISOCYANIDES in [Zhang, Wei; Lin, Jin-Hong; Xiao, Ji-Chang] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Zhang, Pengfei] Cent South Univ, Xiangya Hosp, Dept Oncol, NHC Key Lab Canc Prote, 87 Xiangya Rd, Changsha 410008, Hunan, Peoples R China in 2020, Cited 57. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

For the dehydroxylation of aldoximes with 4-nitro-1-((trifluoromethyl)sulfonyl)-imidazole (NTSI), slight modifications of reaction conditions resulted in significantly different reaction paths to provide either nitriles or isonitriles. The challenging conversion of aldoximes into isonitriles was achieved under mild conditions.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Zhang, W; Lin, JH; Zhang, PF; Xiao, JC or concate me.. Product Details of 86-29-3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Old Concepts, New Application – Additive-Free Hydrogenation of Nitriles Catalyzed by an Air Stable Alkyl Mn(I) Complex WOS:000492768500001 published article about MOLECULAR-ORBITAL METHODS; GAUSSIAN-TYPE BASIS; PRIMARY AMINES; SELECTIVE HYDROGENATION; EQUILIBRIUM GEOMETRIES; INSERTION REACTIONS; HYDROFORMYLATION; HYDROGENOLYSIS; APPROXIMATION; ALDEHYDES in [Weber, Stefan; Kirchner, Karl] Vienna Univ Technol, Inst Appl Synthet Chem, Getreidemarkt 9-163-AC, A-1060 Vienna, Austria; [Veiros, Luis F.] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal in 2019, Cited 56. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Recommanded Product: 2,2-Diphenylacetonitrile

An efficient additive-free manganese-catalyzed hydrogenation of nitriles to primary amines with molecular hydrogen is described. The pre-catalyst, a well-defined bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dpre)(CO)(3)(CH3)] (dpre=1,2-bis(di-n-propylphosphino)ethane), undergoes CO migratory insertion into the manganese-alkyl bond to form acyl complexes which upon hydrogenolysis yields the active coordinatively unsaturated Mn(I) hydride catalyst [Mn(dpre)(CO)(2)(H)]. A range of aromatic and aliphatic nitriles were efficiently and selectively converted into primary amines in good to excellent yields. The hydrogenation of nitriles proceeds at 100 degrees C with a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar. Mechanistic insights are provided by means of DFT calculations.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Weber, S; Veiros, LF; Kirchner, K or concate me.. Recommanded Product: 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem