Day: October 26, 2021

An article Efficient and selective oxidation of tertiary benzylic C-H bonds with O-2 catalyzed by metalloporphyrins under mild and solvent-free conditions WOS:000536139700006 published article about METAL-ORGANIC FRAMEWORKS; AEROBIC OXIDATION; CARBON NANOTUBES; CYCLOHEXANE OXIDATION; GREEN CHEMISTRY; PORPHYRINS; NITROGEN; CUMENE; PRINCIPLES; MECHANISM in [Shen, Hai-Min; Hu, Meng-Yun; Liu, Lei; Qi, Bei; Ye, Hong-Liang; She, Yuan-Bin] Zhejiang Univ Technol, Coll Chem Engn, State Key Lab Breeding Base Green Chem Synth Tech, Hangzhou 310014, Peoples R China in 2020.0, Cited 65.0. Application In Synthesis of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

The direct and efficient oxidation of tertiary benzylic C-H bonds to alcohols with O-2 was accomplished in the presence of metalloporphyrins as catalysts under solvent-free and additive-free conditions. Based on effective inhibition on the unselective autoxidation and deep oxidation, systematical investigation on the effects of porphyrin ligands and metal centers, and apparent kinetics study, the oxidation system employing porphyrin manganese(II) (T(2,3,6-triCl)PPMn) with bulkier substituents as catalyst, was regarded as the most promising and efficient one. For the typical substrate, the conversion of cumene could reach up to 57.6% with the selectivity of 70.5% toward alcohol, both of them being higher than the current documents under similar conditions. The superiority of T(2,3,6-triCl)PPMn was mainly attributed to its bulkier substituent groups preventing metalloporphyrins from oxidative degradation, its planar structure favoring the interaction between central metal with reactants, and the high efficiency of Mn(II) in the catalytic transformation of hydroperoxides to alcohols.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shen, HM; Hu, MY; Liu, L; Qi, B; Ye, HL; She, YB or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2020 EUR J ORG CHEM published article about REDUCTIVE ELIMINATION; CARBON-CARBON; NITRILES; CYANOACETATE; HALIDES; LIGAND; HETEROARYL; COMPLEXES; EFFICIENT; ACETONE in [Yuen, On Ying; Chen, Xiangmeng; Wu, Junyu; So, Chau Ming] Hong Kong Polytech Univ, State Key Lab Chem Biol & Drug Discovery, Hung Hom, Kowloon, Hong Kong, Peoples R China; [Yuen, On Ying; Chen, Xiangmeng; Wu, Junyu; So, Chau Ming] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hung Hom, Kowloon, Hong Kong, Peoples R China; [So, Chau Ming] Hong Kong Polytech Univ, Shenzhen Res Inst, Shenzhen, Peoples R China in 2020, Cited 49. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3. Safety of 2,2-Diphenylacetonitrile

The first general palladium-catalyzed alpha-arylation of arylacetonitriles with aryl and heteroaryl sulfonates are reported. Pd(OAc)(2) associated with XPhos serves as the effective catalyst to facilitate this reaction. A broad range of electron-rich, -neutral, -deficient, and sterically hindered aryl/heteroaryl tosylates and mesylates are coupled with arylacetonitriles bearing different substituents to give the corresponding products in good to excellent yields. Catalyst loading down to 0.1 mol-% Pd was achieved, and 22 unprecedented compounds were synthesized from 43 demonstrated examples using this method. Its applicability with the modification of biological phenolic compounds was successfully demonstrated. The Pd/XPhos system catalyzed the alpha-arylation and followed by alkylation in one-pot sequential conditions, resulting in the direct synthesis of compounds containing quaternary center- and deuterium-containing compounds in good to excellent yields.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Yuen, OY; Chen, XM; Wu, JY; So, CM or concate me.. Safety of 2,2-Diphenylacetonitrile

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 GREEN CHEM published article about MOLECULAR-OXYGEN; SELECTIVE OXIDATION; BENZYLIC ALCOHOLS; BUILDING-BLOCKS; METAL-CATALYSTS; ALDEHYDES; MILD; POLYOXOMETALATE; KETONES; GREEN in [Wei, Zheyu; Ru, Shi; Zhao, Qixin; Yu, Han] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China; [Yu, Han; Wei, Yongge] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China; [Zhang, Gang] Sichuan Univ, Inst Mat Sci & Technol, Chengdu 610064, Sichuan, Peoples R China; [Zhang, Gang] Sichuan Univ, Analyt & Testing Ctr, Chengdu 610064, Sichuan, Peoples R China in 2019.0, Cited 66.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Name: 1-(4-Nitrophenyl)ethanone

The oxidation of alcohols to aldehydes or ketones is a highly relevant conversion for the pharmaceutical and fine-chemical industries, and for biomass conversion, and is commonly performed using stoichiometric amounts of highly hazardous oxidants. The aerobic oxidation of alcohols with transition metal complex catalysts previously required complicated organic ligands and/or nitroxyl radicals as co-catalysts. Herein, we report an efficient and eco-friendly method to promote the aerobic oxidation of alcohols using an inorganic-ligand supported copper catalyst 1, (NH4)(4)[CuMo6O18(OH)(6)], with O-2 (1 atm) as the sole oxidant. Catalyst 1 is synthesized directly from cheap and commonly available (NH4)(6)Mo7O24 center dot 4H(2)O and CuSO4, which consists of a pure inorganic framework built from a central Cu-II core supported by six (MoO6)-O-VI inorganic scaffolds. The copper catalyst 1 exhibits excellent selectivity and activity towards a wide range of substrates in the catalytic oxidation of alcohols, and can avoid the use of toxic oxidants, nitroxyl radicals, and potentially air/moisture sensitive and complicated organic ligands that are not commercially available. Owing to its robust inorganic framework, catalyst 1 shows good stability and reusability, and the catalytic oxidation of alcohols with catalyst 1 could be readily scaled up to gram scale with little loss of catalytic activity, demonstrating great potential of the inorganic-ligand supported Cu catalysts in catalytic chemical transformations.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wei, ZY; Ru, S; Zhao, QX; Yu, H; Zhang, G; Wei, YG or concate me.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Three-Component, Interrupted Radical Heck/Allylic Substitution Cascade Involving Unactivated Alkyl Bromides published in 2020. Computed Properties of C14H11N, Reprint Addresses Glorius, F (corresponding author), Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany.. The CAS is 86-29-3. Through research, I have a further understanding and discovery of 2,2-Diphenylacetonitrile

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable beta-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 a). Sequential C(sp(3))-C(sp(3)) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Huang, HM; Bellotti, P; Pfluger, PM; Schwarz, JL; Heidrich, B; Glorius, F or concate me.. Computed Properties of C14H11N

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019.0 J CATAL published article about DRUG-DELIVERY SYSTEM; PHOTOREDOX CATALYSIS; HYDROGEN-PRODUCTION; METAL-COMPLEXES; ALKYLATION; ORGANOCATALYSIS; PHOTOOXIDATION; CHALLENGES; OXIDATION; DRIVEN in [Gonzalez-Munoz, Daniel; Casado-Sanchez, Antonio; Aleman, Jose] Univ Autonoma Madrid, Sci Fac, Organ Chem Dept, E-28049 Madrid, Spain; [del Hierro, Isabel; Gomez-Ruiz, Santiago] Univ Rey Juan Carlos, Escuela Super Ciencias Expt & Tecnol, Dept Biol & Geol Fis & Quim Inorgan, Madrid 28933, Spain; [Cabrera, Silvia] Univ Autonoma Madrid, Sci Fac, Inorgan Chem Dept, E-28049 Madrid, Spain; [Cabrera, Silvia; Aleman, Jose] Univ Autonoma Madrid, Inst Adv Res Chem Sci IAdChem, E-28049 Madrid, Spain in 2019.0, Cited 43.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

The grafting of a Pt(II) photocatalyst into three different mesoporous silica-based materials with different particle sizes and pore sizes was easily achieved through an amide bond formation. The analysis and results of the different characterization techniques showed that the catalyst is immobilized inside the pores of the materials and the photophysical properties of the catalyst are preserved after the covalent anchoring. The photocatalytic material catalyzed efficiently the debromination reaction of different substrates and is reused without detriment in its catalytic activity. In addition, the incorporation of the catalyst into mesoporous silica materials with different pore size allows the selective debromination of substrates by size discrimination. (C) 2019 Elsevier Inc. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Gonzalez-Munoz, D; Casado-Sanchez, A; del Hierro, I; Gomez-Ruiz, S; Cabrera, S; Aleman, J or concate me.. Product Details of 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 1-(4-Nitrophenyl)ethanone. I found the field of Chemistry very interesting. Saw the article Palladium/Acid Relay Catalyzed Tandem Heck Coupling/6-Endo Cyclization between ortho-Halogenated Benzoates and Unactivated Terminal Alkenes for the Synthesis of 1-Isochromanones published in 2019.0, Reprint Addresses Wen, ZK (corresponding author), Shanxi Univ, Sch Chem & Chem Engn, Taiyuan 030006, Shanxi, Peoples R China.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

We report a unique and expeditious route to synthesize 1-isochromanone derivatives through palladium catalyzed tandem Heck coupling/6-endo hydroacyloxylation cyclization between readily available ortho-halogenated benzoates and unactivated alkenes. Various 2-bromo or 2-iodo benzoates can be coupled efficiently with a broad range of alkenes to afford functionalized 1-isochromanones in high yields. Significantly, this cost-efficient and easy-to-handle synthetic methodology will have great prospect application in the synthetic and medicinal chemistry.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Wen, ZK; Ge, XM; Zhao, ZK; Chao, JB or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Synthesis, Spectroscopic Characterization, DFT Calculations and Preliminary Antifungal Activity of New Piperine Derivatives published in 2021.0. Category: benzodioxans, Reprint Addresses Barbosa, JM (corresponding author), Univ Fed Paraiba, Dept Ciencias Farmaceut, BR-58051900 Joao Pessoa, PB, Brazil.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

Four new piperine derivatives, PC1-PC4, were synthesized, and their structures were fully characterized by infrared (IR) and H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopies. Quantum chemical calculations were performed using density functional theory (DFT) with the B3LYP-D3/6-31G(d,p) and 6-311+G(2d,p) basis sets. Electronic properties, such as the energy gap between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) and some global chemical reactivity descriptors, were evaluated to study the reactivity and stability of the compounds. H-1 and C-13 NMR chemical shifts were calculated by using the gauge-invariant atomic orbital (GIAO) method and compared with experimental values. In addition, the compounds were evaluated in an antifungal study against Candida, Trichophyton and Microsporum strains, and only PC4 showed 70% inhibition in ten tested strains, with a minimum inhibitory concentration (MIC) ranging from 1.23-2.46 mu mol mL(-1) and a minimum fungicide concentration (MFC) ranging from 9.84-19.68 mu mol mL(-1), and presented a fungistatic effect.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Souza, JS; Martins, EPS; Souza, HDS; de Oliveira, RF; Alves, FS; Lima, EO; Cordeiro, LV; Trindade, EO; Lira, BF; Rocha, GB; de Athayde, PF; Barbosa, JM or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

SDS of cas: 100-19-6. Bahrami, K; Khodaei, MM; Batooie, N; Hosseinzadeh, N; Foroumadi, A in [Bahrami, Kiumars; Khodaei, Mohammad M.; Batooie, Nasim] Razi Univ, Fac Chem, Dept Organ Chem, Kermanshah 6714967346, Iran; [Hosseinzadeh, Nouraddin] Sharif Univ Technol, Dept Chem, Lab Organ Synth & Nat Prod, Azadi St,POB 11155-9516, Tehran, Iran; [Foroumadi, Alireza] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran, Iran published Hexyltriphenylphosphonium Bromide as an Absolutely Chemoselective Ionic Liquid Catalyst in the Three-Component Reaction of Aryl Aldehydes, Acetophenones and Malononitrile in 2019.0, Cited 44.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Hexyltriphenylphosphonium bromide (HTPB) is used as an efficient ionic liquid catalyst in the chemoselective addition of malononitrile to carbonyl group moiety of chalcones through the three-component reaction of aryl aldehydes, acetophenone derivatves, and malononitrile to produce (E)-2-(1,3-diarylallylidene)malononitriles at ambient temperature. The method is simple, solvent-free, environmentally friendly, and gives excellent yields in a short reaction times.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Bahrami, K; Khodaei, MM; Batooie, N; Hosseinzadeh, N; Foroumadi, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2019 ACS CATAL published article about AMINATION in [Chen, Wei; Chen, Kai; Chen, Wanzhi] Zhejiang Univ, Dept Chem, 38 Zheda Rd, Hangzhou 310027, Peoples R China; [Liu, Miaochang; Wu, Huayue] Wenzhou Univ, Coll Chem & Mat Engn, 588 New Chaoyang St, Wenzhou 325027, Peoples R China in 2019, Cited 33. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. SDS of cas: 100-19-6

The C-N bond formation is one of the fundamental reactions in organic chemistry, because of the widespread presence of amine moieties in pharmaceuticals and biologically active compounds. Palladium-catalyzed C-N coupling of haloarenes represents one of the most efficient approaches to aromatic amines. Nitroarenes are ideal alternative electrophilic coupling partners, since they are inexpensive and readily available. The denitration and cross-coupling using nitroarenes as the electrophilic partners is challenging, because of the low reactivity of the Ar-NO2 bond toward oxidative addition. We report here the C-N coupling of nitroarenes and amines using palladium/5-(2,4,6-triisopropylphenyl)imidazolylidene[1,5-a]pyridines as the catalyst. The ligands are readily available from commercial chemicals. The reaction shows broad substrate scope and functional group tolerance. The method is applicable to both aromatic and aliphatic amines, and many secondary and tertiary aromatic amines bearing various functional groups were obtained in high yields.

SDS of cas: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chen, W; Chen, K; Chen, WZ; Liu, MC; Wu, HY or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Authors Monsen, PJ; Luzzio, FA in PERGAMON-ELSEVIER SCIENCE LTD published article about PORPHYROMONAS-GINGIVALIS ADHERENCE; 1,2,3-TRIAZOLE-BASED INHIBITORS; ORAL STREPTOCOCCI; PROSTAGLANDINS in [Monsen, Paige J.; Luzzio, Frederick A.] Univ Louisville, Dept Chem, 2320 South Brook St, Louisville, KY 40292 USA in 2020, Cited 25. Formula: C8H7NO3. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

An array of arylnitro compounds with various functionality were treated with freshly-prepared aluminum amalgam in THE/water solution and resulted in the corresponding arylamines. The Al(Hg)-mediated reductions are relatively rapid with consumption of the amalgam and disappearance of starting material occurring over 20-30 min. The workup of the reductions involves only removal of the insoluble by-products by filtration followed by concentration. Only in some cases is chromatography required to secure the pure product. The desired arylamines are furnished in quantities of 25-100 mg, which in some cases, could be taken on to the next reaction without further purification. Reductions of 4-nitrobenzyl derivatives of carbohydrates or nucleosides were selective in affording the corresponding 4-aminobenzyl products. To show applicability in click chemistry, selected aminobenzyl products are directly azidated to yield products that were then used in click reactions to afford the corresponding 1,2,3-triazoles. (C) 2020 Elsevier Ltd. All rights reserved.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Monsen, PJ; Luzzio, FA or concate me.. Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem