Day: October 18, 2021

Recommanded Product: 1-(4-Nitrophenyl)ethanone. Recently I am researching about AROMATIC NITRO-COMPOUNDS; PHOTOCATALYTIC REDUCTION; CHEMOSELECTIVE REDUCTION; SELECTIVE HYDROGENATION; SUPPORTED PLATINUM; MESOPOROUS SBA-15; ACTIVE CATALYST; NANOPARTICLES; EFFICIENT; COPPER, Saw an article supported by the DST-Fast Track Young Scientist scheme [SB/FT/CS-95/2014]; SERB-EMEQ [SB/EMEQ-297/2014]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Thennila, M; Muthumanickam, S; Sivabharathy, M; Yuvaraj, P; Selvakumar, K. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A strategy for heterogeneous copper(I) mesoporous silica [Cu(I)-SBA-15] mediated catalytic reduction has been developed for the reduction of various nitroarenes in excellent yields. In addition to alcothermal strategy, other strategies have been attempted for the preparation of Cu(I) substituted mesoporous silica, however, the desired oxidation state is obtained only through alcothermal strategy. The crystalline phases and oxidation state of synthesized materials were characterized by XRD and XPS measurements and tested for catalytic reduction of nitroarenes. Among the tested materials, the best catalytic reduction of nitroarenes with an excellent substrate scope and good catalytic reusability was established by Cu(I)-SBA-15 material. The reduction kinetics and the controlled experimental studies reveal that the reaction proceeds through pseudo-first-order kinetics and nitrosobenzene intermediate pathway.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Thennila, M; Muthumanickam, S; Sivabharathy, M; Yuvaraj, P; Selvakumar, K or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Ma, Q; Wang, YH; Tsui, GC in [Ma, Qiao; Wang, Yanhui; Tsui, Gavin Chit] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China published Stereoselective Palladium-Catalyzed C-F Bond Alkynylation of Tetrasubstituted gem-Difluoroalkenes in 2020.0, Cited 69.0. Name: 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A stereoselective Pd(PPh3)(4)-catalyzed C-F bond alkynylation of tetrasubstituted gem-difluoroalkenes with terminal alkynes has been developed. This method gives access to a great variety of conjugated monofluoroenynes bearing a tetrasubstituted alkene moiety with well-defined stereochemistry. Chelation-assisted oxidative addition of Pd to the C-F bond is proposed to account for the high level of stereocontrol. An X-ray crystal structure of a key monofluorovinyl Pd-II intermediate has been obtained for the first time as evidence for the proposed mechanism.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Ma, Q; Wang, YH; Tsui, GC or concate me.. Name: 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Metal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategy WOS:000463784900019 published article about AROMATIC NITRO-COMPOUNDS; SOLVENT-FREE; SELECTIVE REDUCTION; EFFICIENT REDUCTION; CATALYZED REDUCTION; SUPPORTED GOLD; MEDIATED REDUCTION; SODIUM-BOROHYDRIDE; HIGHLY EFFICIENT; AMINE FORMATION in [Shuai, Qi; Li, Jun; Su, Weike] Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Zhejiang, Peoples R China; [Shuai, Qi; Su, Weike] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China; [Zhao, Feng; Deng, Guojun] Xiangtan Univ, Coll Chem, Key Lab Environm Friendly Chem & Applicat, Minist Educ, Xiangtan 411105, Peoples R China in 2019, Cited 85. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

A novel protocol for chemoselective reduction of aromatic nitro compounds to aromatic amines has been established. The metal-free reduction goes through a hydrogen transfer process. Various easily reducible functional groups can be well tolerated under the optimized reaction conditions.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Shuai, Q; Li, J; Zhao, F; Su, WK; Deng, GJ or concate me.. Recommanded Product: 100-19-6

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about TRANSFER HYDROGENATION; PHOTOREDOX CATALYSIS; ALKYLATION; 4-ALKYL-1,4-DIHYDROPYRIDINES; DEBROMINATION; HETEROCYCLES; REDUCTIONS; OXIDES, Saw an article supported by the . HPLC of Formula: C8H7NO3. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Konev, MO; Cardinale, L; Jacobi von Wangelin, A. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A mild and operationally simple protocol for the deoxygenation of a variety of heteroaryl N-oxides and nitroarenes has been developed. A mixture of substrate and Hantzsch ester is proposed to result in an electron donor-acceptor complex, which upon blue-light irradiation undergoes photoinduced electron transfer between the two reactants to afford the products. N-oxide deoxygenation is demonstrated with 22 examples of functionally diverse substrates, and the chemoselective reduction of nitroarenes to the corresponding hydroxylamines is also shown.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Konev, MO; Cardinale, L; Jacobi von Wangelin, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recommanded Product: 86-29-3. Authors Maddocks, CJ; Ermanis, K; Clarke, PA in AMER CHEMICAL SOC published article about in [Maddocks, Christopher J.; Clarke, Paul A.] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England; [Ermanis, Kristaps] Univ Cambridge, Ctr Mol Informat, Dept Chem, Cambridge CB2 1EW, England in 2020, Cited 62. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3

The development of an asymmetric clip-cycle synthesis of 2,2- and 3,3-disubstituted pyrrolidines and spiropyrrolidines, which are increasingly important scaffolds in drug discovery programs, is reported. Cbz-protected bis-homoallylic amines were activated by clipping them to thioacrylate via an alkene metathesis reaction. Enantioselective intramolecular azaMichael cyclization onto the activated alkene, catalyzed by a chiral phosphoric acid, formed a pyrrolidine. The reaction accommodated a range of substitutions to form 2,2- and 3,3-disubstituted pyrrolidines and spiropyrrolidines with high enantioselectivities. The importance of the thioester activating group was demonstrated by comparison to ketone and oxoestercontaining substrates. DFT studies supported the aza-Michael cyclization as the rate- and stereochemistry-determining step and correctly predicted the formation of the major enantiomer. The catalytic asymmetric syntheses of N-methylpyrrolidine alkaloids (R)irnidine and (R)-bgugaine, which possess DNA binding and antibacterial properties, were achieved using the clip-cycle methodology.

Recommanded Product: 86-29-3. About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Maddocks, CJ; Ermanis, K; Clarke, PA or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Recently I am researching about SELECTIVE SYNTHESIS; PENTAARYLPYRIDINES; ARYLPYRIDINES; CONSTRUCTION; CONDENSATION; DERIVATIVES; ENAMINES; KINETICS; BINDING, Saw an article supported by the . Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Arita, M; Yokoyama, S; Asahara, H; Nishiwaki, N. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone. Recommanded Product: 1-(4-Nitrophenyl)ethanone

Condensation of beta-(2-pyridyl)enamine and alpha,beta-unsaturated ketone in the presence of FeCl3 under air afforded highly substituted pyridines. In this transformation, FeCl3 acted as not only an acid catalyst but also an oxidant for the intermediate dihydropyridine. The substituents could be easily modified by altering the substrates to obtain tri- and tetraarylpyridines including bipyridines and terpyridine. Synthesis of differently substituted pentaarylpyridines was consequently achieved via only three steps from commercially available reagents with simple experimental manipulations.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Arita, M; Yokoyama, S; Asahara, H; Nishiwaki, N or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. In 2019.0 CHEM SCI published article about DNA CROSS-LINKING; FLUORESCENT-PROBES; ROS; AGENTS; MUSTARD; DAMAGE in [Meng, Tingting; Zhang, Pengfei; Hu, Jing; Fu, Junjie; Yin, Jian] Jiangnan Univ, Sch Biotechnol, Key Lab Carbohydrate Chem & Biotechnol, Minist Educ, Wuxi 214122, Jiangsu, Peoples R China; [Meng, Tingting; Fu, Junjie] Nanjing Med Univ, Sch Pharm, Nanjing 211166, Jiangsu, Peoples R China; [Han, Jing] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China in 2019.0, Cited 44.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

Leveraging the elevated levels of hydrogen peroxide (H2O2) in cancer, inflammatory diseases and cardiovascular disorders, H2O2-activated promoieties have been widely used in drugs and biomaterials design. However, the overwhelming majority of the promoieties only share the common structure of a H2O2-responsive arylboronic acid/ester moiety with low diversity. We report here an unprecedented strategy to construct novel H2O2-responsive prodrugs based on an alpha-ketoamide structure. As a proof of concept, we designed and synthesized a panel of alpha-ketoamide based nitrogen mustard prodrugs, among which KAM-2 showed potent growth inhibitory activity and high selectivity toward cancer cells. The H2O2-trigged decomposition of KAM-2 was validated, and the DNA damaging and apoptosis promoting activity attributed to the released nitrogen mustard were demonstrated. Our work unveils alpha-ketoamide as a new scaffold for prodrug design and may quickly inspire future developments.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Meng, TT; Han, J; Zhang, PF; Hu, J; Fu, JJ; Yin, J or concate me.. HPLC of Formula: C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Product Details of 86-29-3. Mudshinge, SR; Potnis, CS; Xu, B; Hammond, GB in [Mudshinge, Sagar R.; Potnis, Chinmay S.; Hammond, Gerald B.] Univ Louisville, Dept Chem, Louisville, KY 40292 USA; [Xu, Bo] Donghua Univ, Coll Chem Chem Engn & Biotechnol, 2999 North Renmin Lu, Shanghai, Peoples R China published HCl center dot DMPU-assisted one-pot and metal-free conversion of aldehydes to nitriles in 2020, Cited 41. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

We report an efficient HCl center dot DMPU assisted one-pot conversion of aldehydes into nitriles. The use of HCl center dot DMPU as both an acidic source as well as a non-nucleophilic base constitutes an environmentally mild alternative for the preparation of nitriles. Our protocol proceeds smoothly without the use of toxic reagents and metal catalysts. Diverse functionalized aromatic, aliphatic and allylic aldehydes incorporating various functional groups were successfully converted to nitriles in excellent to quantitative yields. This protocol is characterized by a broad substrate scope, mild reaction conditions, and high scalability.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Mudshinge, SR; Potnis, CS; Xu, B; Hammond, GB or concate me.. Product Details of 86-29-3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Zhang, LK; Wang, JM; Shang, NZ; Gao, ST; Gao, YJ; Wang, C in [Zhang, Longkang; Wang, Junmin; Shang, Ningzhao; Gao, Shutao; Wang, Chun] Hebei Agr Univ, Coll Sci, Baoding 071001, Peoples R China; [Gao, Yongjun] Univ Hebei, Coll Chem & Environm Sci, Baoding 071002, Peoples R China published Ultra dispersed cobalt anchored on nitrogen-doping ordered porous carbon as an efficient transfer hydrogenation catalyst in 2019.0, Cited 52.0. Quality Control of 1-(4-Nitrophenyl)ethanone. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

A non-noble heterogeneous catalyst, ultra dispersed Co anchored on ordered porous nitrogen-riched carbon (CoN@PCN) was fabricated through a sacrificial-template pyrolysis strategy, in which SBA-15 and 1, 10-phenanthroline were employed as the hard template and ligand, respectively. Co was ultra dispersed owing to the confinement effect of SBA-15 and the strong coordination effect of Co with phenanthroline. The CoN@PCN displayed excellent catalytic activity and selectivity for the hydrogenation of nitroarenes with ammonia-borane as hydrogen donor under mild conditions, which can be ascribed to the ultra dispersed Co sites, high adsorption ability of the catalyst for ammonia-borane, large specific surface area and abundant porous structure of CoN@PCN. Based on the results of density functional theory calculations, the catalytic mechanism of CoN@PCN for the hydrogenation reaction was proposed. The recycled CoN@PCN had no obvious change in catalytic performance after five consecutive cycles, indicating its durability and recyclability.

Quality Control of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, LK; Wang, JM; Shang, NZ; Gao, ST; Gao, YJ; Wang, C or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Computed Properties of C8H7NO3. Recently I am researching about BEARING BENZOTHIAZOLE; ANTITUMOR-ACTIVITY; IN-VITRO; DERIVATIVES; THIOPHENE; PYRIDINE; HETEROCYCLES; INHIBITORS; THIAZOLE; MOIETY, Saw an article supported by the . Published in WILEY in HOBOKEN ,Authors: Hassan, AY; Sarg, MT; Hussein, EM. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

On the pharmaceutical account of the reported anticancer activity of benzothiazole derivatives, differently substituted benzothiazole derivatives 2a-c to 34a,b, attached at 2-position to different heterocyclic moieties, were synthesized via different chemical reactions. Thirteen of the newly synthesized compounds were selected by the National Cancer Institute, Bethesda, Maryland, USA, and evaluated for their in vitro antitumor activity against 60 human tumor cell lines in a one-dose screening panel among which two compounds 4 and 17 showed high activity and were selected for further evaluation in the five-dose full panel assay, in which compound 4 exerted powerful growth inhibitory activity against all cell lines with GI(50) ranging from 0.683 to 4.66 mu M/L in addition to excellent lethal activity against most of the cell lines.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Hassan, AY; Sarg, MT; Hussein, EM or concate me.. Computed Properties of C8H7NO3

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem