Month: September 2021

Computed Properties of C14H11N. Akasapu, K; Ojah, N; Gupta, AK; Choudhury, AJ; Mishra, P in [Akasapu, Kumudhini; Gupta, Arun Kumar; Mishra, Poonam] Tezpur Univ, Dept Food Engn & Technol, Tezpur 784028, Assam, India; [Ojah, Namita; Choudhury, Arup Jyoti] Tezpur Univ, Dept Phys, Tezpur 784028, Assam, India published An innovative approach for iron fortification of rice using cold plasma in 2020, Cited 24. The Name is 2,2-Diphenylacetonitrile. Through research, I have a further understanding and discovery of 86-29-3.

In the present study, an innovative cold plasma treatment was used as a tool to fortify the white rice. The amounts of ferrous sulphate and ascorbic acid were optimized for improving the bioavailability of iron. White rice samples were treated with plasma at a constant voltage of 20 kV for varying time (10 min and 15 min). The exposure time of plasma was selected based on the surface characteristics, hydrophilicity and thermal properties. Significant improvement was observed in the characteristics of hydrophilicity, surface energy, cooking time and hardness of plasma-treated rice. Plasma treated rice was fortified with the optimum concentrations of iron and ascorbic acid solution. Optimum concentrations of iron and ascorbic acid per 100 g of rice (862.93 mg and 1398.27 mg) were found by conducing experiments using Central Composite Design of Response Surface Methodology. Further, rice was blended with untreated rice in the ratio of 1:100 and 1:200 and was packed in LDPE and PP pouches and was stored at ambient temperature for further storage analysis. The in vitro bioavailability of iron was significantly higher in the plasma-treated fortified rice at both 1.35 and 7.5 pH than in the control sample, and plasma treatment significantly reduced the rate of oxidation of iron during storage.

About 2,2-Diphenylacetonitrile, If you have any questions, you can contact Akasapu, K; Ojah, N; Gupta, AK; Choudhury, AJ; Mishra, P or concate me.. Computed Properties of C14H11N

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Cobalt single atoms anchored on N-doped ultrathin carbon nanosheets for selective transfer hydrogenation of nitroarenes WOS:000485550400008 published article about FUNCTIONALIZED NITROARENES; CATALYTIC-HYDROGENATION; REDUCTION; EFFICIENT; ALLOYS in [Li, Huining; Cao, Changyan; Liu, Jian; Shi, Yang; Song, Weiguo] Chinese Acad Sci, CAS Res Educ Ctr Excellence Mol Sci, Beijing Natl Lab Mol Sci, Lab Mol Nanostruct & Nanotechnol,Inst Chem, Beijing 100190, Peoples R China; [Li, Huining; Cao, Changyan; Liu, Jian; Shi, Yang; Song, Weiguo] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Si, Rui] Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchroton Radiat Facil, Shanghai 201204, Peoples R China; [Gu, Lin] Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, Beijing 100190, Peoples R China in 2019.0, Cited 55.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Safety of 1-(4-Nitrophenyl)ethanone

Selective transfer hydrogenation of nitroarenes to amines with transition metal nanocatalysts is appealing due to its low-cost, moderate reaction conditions, good activity and excellent selectivity. Single-atom catalysts (SACs) possessing advantages of maximum atom efficiency and particular electronic structure are expected to be more effective for this reaction, yet no report about it. Herein, cobalt single atoms anchored on N-doped ultrathin carbon nanosheets (denoted as CoSAs/NCNS) were produced and demonstrated as an outstanding SAC for selective transfer hydrogenation of nitroarenes to amines with formic acid as hydrogen donor. The turnover frequency (TOF) reached 110.6 h(-1), which was 20 times higher than the best results of cobalt nanoparticles reported in literatures under similar reaction conditions. Moreover, CoSAs/NCNS exhibited excellent selectivity for a variety of nitroarenes bearing other reducible functionalities, such as iodo, cyano, keto, vinyl, alkynyl and ester groups. The findings further highlight the ability and advantages of SACs in heterogeneous catalysis.

Safety of 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Li, HN; Cao, CY; Liu, J; Shi, Y; Si, R; Gu, L; Song, WG or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

COA of Formula: C8H7NO3. I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Antiproliferative effects of chalcones on T cell acute lymphoblastic leukemia-derived cells: Role of PKC beta published in 2020.0, Reprint Addresses Rimoldi, I; Christodoulou, MS (corresponding author), Univ Milan, DISFARM, Sez Chim Gen & Organ A Marchesini, Via Venezian 21, I-20133 Milan, Italy.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone.

In this study, a series of 20 chalcone derivatives was synthesized, and their antiproliferative activity was tested against the human T cell acute lymphoblastic leukemia-derived cell line, CCRF-CEM. On the basis of the structural features of the most active compounds, a new library of chalcone derivatives, according to the structure-activity relationship design, was synthesized, and their antiproliferative activity was tested against the same cancer cell line. Furthermore, four of these derivatives (compounds 3, 4, 8, 28), based on lower IC50 values (between 6.1 and 8.9 mu M), were selected for further investigation regarding the modulation of the protein expression of RACK1 (receptor for activated C kinase), protein kinase C (PKC)alpha and PKC beta, and their action on the cell cycle level. The cell cycle analysis indicated a block in the G0/G1 phase for all four compounds, with a statistically significant decrease in the percentage of cells in the S phase, with no indication of apoptosis (sub-G0/G1 phase). Compounds 4 and 8 showed a statistically significant reduction in the expression of PKC alpha and an increase in PKC beta, which together with the demonstration of an antiproliferative role of PKC beta, as assessed by treating cells with a selective PKC beta activator, indicated that the observed antiproliferative effect is likely to be mediated through PKC beta induction.

COA of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Corsini, E; Facchetti, G; Esposito, S; Maddalon, A; Rimoldi, I; Christodoulou, MS or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

Category: benzodioxans. In 2020.0 J MOL LIQ published article about IONIC-LIQUID; NITROBENZENE HYDROGENATION; PALLADIUM NANOPARTICLES; HETEROGENEOUS CATALYST; PHOSPHOMOLYBDIC ACID; HALLOYSITE NANOTUBES; GOLD NANOPARTICLES; HIGHLY EFFICIENT; REDUCTION; KNOEVENAGEL in [Sadjadi, Samahe; Koohestani, Fatemeh] Iran Polymer & Petrochem Inst, Fac Petrochem, Gas Convers Dept, POB 14975-112, Tehran, Iran in 2020.0, Cited 47.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6.

y A novel polymeric network benefiting from the chemistry of imidazolium salt (IL), cyclodextrin (CD) and carbon nanotube (CNT) is fabricated through a multi-step process, in which silica coated CNTs were vinyl functionalized and polymerized with poly (ethylene glycol) dimethacrylate and CD-IL, prepared from the reaction of vinyl imidazole and tosylated CD. The resulting hybrid system, CNT-P, was then used as a support for the immobilization of Pd nanoparticles and furnishing a heterogeneous catalyst, Pd@CNT-P, with the utility for the hydrogenation of nitroarenes in aqueous media. The catalyst exhibited high catalytic activity and selectivity towards hydrogenation of nitro group. Moreover, it was recyclable up to six reaction runs. Comparing the catalytic activity of the catalyst with that of some control catalysts, the contribution of CD-IL and silica coated CNT to the catalysis has been confirmed. It was believed that CD in the backbone of the catalyst could act as a phase transfer agent, while multiple functional groups on the polymeric moiety improved Pd anchoring and suppressed its leaching. Silica coated CNT on the other hand, allowed better dispersion of Pd nanoparticles and assured fine Pd particle size. (C) 2019 Elsevier B.V. All rights reserved.

Category: benzodioxans. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Sadjadi, S; Koohestani, F or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

In 2021.0 ASIAN J ORG CHEM published article about C-H ACTIVATION; CERIUM(IV) AMMONIUM-NITRATE; BOND ARYLATION; METAL-FREE; MECHANISTIC INSIGHT; MOLECULAR-OXYGEN; HIGHLY EFFICIENT; CROSS; TETRAHYDROISOQUINOLINES; SP(3) in [Zhang, Changyuan; Qiu, Yun; Chen, Lulu; Xu, Shuting; Guo, Huosheng; Luo, Jian; Tan, Yao] Yichun Univ, Jiangxi Univ Appl Chem & Chem Biol, Coll Chem & Bioengn, Key Lab, 576 Xuefu Rd, Yichun 336000, Peoples R China; [Zhang, Jiantao] Guangdong Univ Petrochem Technol, Coll Chem, Guandu Rd, Maoming 525000, Peoples R China in 2021.0, Cited 63.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Recommanded Product: 100-19-6

An efficient CAN-mediated C-C bond formation in the oxidative reactions of xanthenes with enaminones under mild reaction conditions are described. A variety of 9H-xanthene-9-ylidene aldehydes could be synthesized in up to 90% yield via one-pot manner with good functional group compatibility, which achieved the simultaneous construction of carbon-carbon double bond and carbon-oxygen double bond.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Zhang, CY; Qiu, Y; Zhang, JT; Chen, LL; Xu, ST; Guo, HS; Luo, J; Tan, Y or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Novel thiazole-piperazine derivatives as potential cholinesterase inhibitors WOS:000485774300001 published article about TARGET-DIRECTED LIGANDS; BIOLOGICAL EVALUATION; ANTICHOLINESTERASE ACTIVITY; MOLECULAR DOCKING; IN-SILICO; DESIGN; ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTERASE; HYBRIDS; DONEPEZIL in [Demirayak, Seref; Sahin, Zafer; Ertas, Merve; Bulbul, Emre Fatih; Bender, Ceysu; Berk, Barkin] Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Chem, TR-34083 Istanbul, Turkey; [Biltekin, Sevde Nur] Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Microbiol, TR-34083 Istanbul, Turkey; [Saglik, Begum Nurpelin; Levent, Serkan; Yurttas, Leyla] Anadolu Univ, Fac Pharm, Dept Pharmaceut Chem, TR-26470 Eskisehir, Turkey in 2019.0, Cited 46.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Product Details of 100-19-6

Dementia is a cognitive disorder mostly associated with Alzheimer’s disease (AD) in addition to being seen in many other diseases of the central nervous system (CNS). The limited number of drugs is not sufficient to provide adequate improvement to increase the quality of life of patients suffering from this symptom; therefore, all treatment options should be evaluated in detail. In this study, new molecules, [2-(4-(2/3/4-substituted phenyl)piperazin-1-yl)-4-phenylthiazol-5-yl][3/4-substituted phenyl]methanone derivatives (1-44), were obtained and analyzed in terms of their anticholinesterase activities. Kinetic mode and molecular interactions were also evaluated. An enzyme inhibition study was undertaken on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) using the Ellman method. Maestro program was used in molecular modeling studies. Forty-four compounds were evaluated on AChE and BChE enzymes at 10(-3) and 10(-4) concentrations. The inhibition concentrations were calculated as 0.268 mu M to 2.104 mu M for six compounds (4, 5, 16, 27, 37, and 38) on AChE. Compound 5 including the 4-methoxy substituent (IC50: 0.268 mu M) and compound 38 containing the 4-methoxy and 3-methyl substituents (IC50: 0.286 mu M) showed the highest AChE inhibitory activity. They were further examined in terms of hydrogen bonding with Arg296 and Ar-Ar interaction with Trp286. The activity of compound 5 was also assessed in mixed-type kinetic mode.

Product Details of 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Demirayak, S; Sahin, Z; Ertas, M; Bulbul, EF; Bender, C; Biltekin, SN; Berk, B; Saglik, BN; Levent, S; Yurttas, L or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

HPLC of Formula: C8H7NO3. Recently I am researching about AGENTS; BENZOFURANS; OXIDATION, Saw an article supported by the UPCST [CST/D-2276]; IIT (BHU) TA; CSIR, New DelhiCouncil of Scientific & Industrial Research (CSIR) – India. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Singh, M; Yadav, VB; Ansari, MD; Malviya, M; Siddiqui, IR. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

An efficient and facile protocol for the synthesis of a multi-functional 6,7-dihydrobenzofuran-4(5H)-ones and their derivatives using iron salt in the presence of air via reactions of readily available dimedone, acetophenone and isocyanide as starting materials. This approach illustrate operational simplicity, offering a modified and expedient methodology for the direct construction of synthetically useful benzofuran derivatives in good to excellent yields. Benzofuran derivatives have many biological importance. This documented strategy, provide a cost effective and environmentally benign alternative to the other existing method.

HPLC of Formula: C8H7NO3. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Singh, M; Yadav, VB; Ansari, MD; Malviya, M; Siddiqui, IR or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article A Common, Facile and Eco-Friendly Method for the Reduction of Nitroarenes, Selective Reduction of Poly-Nitroarenes and Deoxygenation of N-Oxide Containing Heteroarenes Using Elemental Sulfur WOS:000522338200008 published article about METAL-FREE REDUCTION; AQUEOUS AMMONIUM SULFIDE; NITRO-COMPOUNDS; EFFICIENT DEOXYGENATION; CATALYZED REDUCTION; GENERAL-METHOD; DERIVATIVES; HYDROGENATION; AMINES; PYRIDINE in [Romero, Angel H.; Cerecetto, Hugo] Univ Republica, Inst Quim Biol, Fac Ciencias, Igual 4225, Montevideo 11400, Uruguay in 2020.0, Cited 124.0. Recommanded Product: 100-19-6. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6

A transition metal-free, environment-friendly and practical protocol was developed either for the reduction of nitroarenes or for the deoxygenation of N-oxide containing heteroarenes. The reaction proceeded with the use of a non-toxic and cheap feedstock as elemental sulfur in aqueous methanol under relatively mild conditions. Green chemistry credentials were widely favorable compared to traditional and industrial protocols with good E-factors and a low production of waste. The strategy allowed the efficient reduction of a large variety of substituted-nitroarenes including various o-nitroanilines as well as selective reduction of various poly-nitroarenes in excellent yields with a broad substrate scope. The protocol was successfully extended to the deoxygenation of some N-oxide containing heteroarenes, like benzofuroxans, phenazine N,N-‘-dioxides, pyridine N-oxides, 2H-indazole N-1-oxides, quinoxaline N-1,N-4-dioxides and benzo[d]imidazole N-1,N-3-dioxides. A gram-scale example for the synthesis of luminol, in green conditions, was reported. A solid mechanism of reaction was proposed from experimental evidences.

Recommanded Product: 100-19-6. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Romero, AH; Cerecetto, H or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

An article Synthesis, Crystallographic Structure, Hirshfeld Surface Analysis, Drug-likeness Properties and Molecular Docking Studies of New Oxime-pyridine Compounds WOS:000641761700009 published article about DERIVATIVES in [Topal, Tufan] Pamukkale Univ, Dept Chem, TR-20020 Denizli, Turkey in 2021.0, Cited 73.0. The Name is 1-(4-Nitrophenyl)ethanone. Through research, I have a further understanding and discovery of 100-19-6. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

A detailed description of the two new pyridine ligands, (2E,3Z)-3-[2-(3-chloropyridin-2-yl)hydrazinylidene]-N-hydroxybutan-2-imine and 3-chloro-2-{(2Z)-2-[1-(4 nitrophenyl)ethylidene]hydrazinyl}, is reported. The synthesized compounds were characterized by spectroscopic studies, spectral features were performed by TD-DFT calculations. New-generation pyridine ligand of HL2 was also determinate by single-crystal X-ray diffraction and Hirshfeld surface analysis with two-dimensional fingerprint plots was used to analyze intermolecular interactions in crystals. Molecular-docking was performed to investigate the binding areas of chemical compounds, and the results showed the inhibitory activity of the studied HL1 and HL2 against E. coli. The results of the current study revealed the drug-likeness and bioactive properties of the ligands.

About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Topal, T or concate me.. Application In Synthesis of 1-(4-Nitrophenyl)ethanone

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem

I found the field of Chemistry very interesting. Saw the article Green one-pot multicomponent synthesis, biological evaluation and theoretical investigations of some novel beta-acetamido ketone derivatives as potent cholinesterase inhibitors published in 2020.0. Recommanded Product: 1-(4-Nitrophenyl)ethanone, Reprint Addresses Boulcina, R; Debache, A (corresponding author), Mentouri Constantine 1 Univ, Lab Synth Mol Biol Interest, Constantine 25000, Algeria.. The CAS is 100-19-6. Through research, I have a further understanding and discovery of 1-(4-Nitrophenyl)ethanone

A series of novel beta-acetamido ketones have been prepared via a four-component condensation between aromatic aldehydes, enolizable ketones, acyl chloride and acetonitrile in the presence of 10 mol% of phenylboronic acid as a catalyst. The expected products have been obtained in good to excellent yields. In addition, in vitro cholinesterase inhibitory activity of title compounds has been studied and the results indicated that some compounds exhibited remarkable BChE activity. In order to gain insights into the molecular structure and chemical reactivity of the synthesized beta-acetamido ketones, density functional theory (DFT) calculations were also carried out. (C) 2020 Elsevier Ltd. All rights reserved.

Recommanded Product: 1-(4-Nitrophenyl)ethanone. About 1-(4-Nitrophenyl)ethanone, If you have any questions, you can contact Chibane, AZ; Boulcina, R; Boulebd, H; Bensouici, C; Yildirim, M; Debache, A or concate me.

Reference:
Benzodioxan,
,1,4-Benzodioxane | C8H8O2 – PubChem